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  1. 9721
    “…However, as the pandemic’s dynamics continue to evolve, a balanced approach between caution and resilience becomes paramount. This ethos encourages an approach founded on informed prudence and self-preservation, guided by public health authorities, rather than enduring apprehension. …”
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    Unraveling the Dynamics of Omicron (BA.1, BA.2, and BA.5) Waves and Emergence of the Deltacton Variant: Genomic Epidemiology of the SARS-CoV-2 Epidemic in Cyprus (Oct 2021–Oct 2022)
  2. 9722
    “…We focused on HSPE1, which was designated as the hub gene due to its paramount importance in the SVM model, and computed the docking structures for four compounds: ZINC3978005 (Dihydroergotamine), ZINC52955754 (Ergotamine), ZINC150588351 (Elbasvir), and ZINC242548690 (Digoxin). …”
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    Investigating subtypes of lung adenocarcinoma by oxidative stress and immunotherapy related genes
  3. 9723
    “…Differential click-through rates and increased survey dropout by MSM of color indicate that methods to recruit and retain black and Hispanic MSM in Internet-based research studies are paramount. Although targeting banner advertisements to MSM of color by changing the racial/ethnic composition of the advertisements may increase click-through, decreasing attrition of these study participants once they are engaged in the survey remains a challenge.…”
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    Bias in Online Recruitment and Retention of Racial and Ethnic Minority Men Who Have Sex With Men
  4. 9724
    “…OBJECTIVES: Recognition of modifiable and non-modifiable risk factors for anterior cruciate ligament (ACL) injuries in children and adolescent athletes is paramount to develop effective strategies for prevention and treatment. …”
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    Is Pre-Injury Leg Length Discrepancy A Risk Factor for Anterior Cruciate Ligament Injury in the Skeletally Immature Athlete?
  5. 9725
    “…BACKGROUND: Fast transitions to targeted therapies for infectious disease patients are paramount for optimal patient care and antibiotic stewardship. …”
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    2076. Expanded Antibiotic Menu Demonstration for Novel Rapid Phenotypic Antimicrobial Susceptibility Testing Platform
  6. 9726
    “…A multi-disciplinary approach to such patients is paramount. This case involved team work between rheumatology, dermatology, respiratory medicine and radiology. …”
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    4. A case of SAE-1 dermatomyositis
  7. 9727
    “…Thus, characterizing the digital literacy of hospitalized patients across health literacy levels is paramount. OBJECTIVE: We sought to determine the relationship between health literacy level and technological access, use, and capability among hospitalized patients. …”
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    Evaluating the Need to Address Digital Literacy Among Hospitalized Patients: Cross-Sectional Observational Study
  8. 9728
    “…In this respect, the identification of highly effective and innovative pharmacological strategies is of paramount importance for the treatment and/or prophylaxis of the current pandemic but potentially also for future and unavoidable outbreaks of human pathogenic coronaviruses.…”
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    Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses
  9. 9729
    “…BACKGROUND: Understanding the occurrence of symptoms resembling those of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a large nonhospitalized population at the peak of the epidemic in Italy is of paramount importance; however, data are currently scarce. …”
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    Self-Reported Symptoms of SARS-CoV-2 Infection in a Nonhospitalized Population in Italy: Cross-Sectional Study of the EPICOVID19 Web-Based Survey
  10. 9730
    “…SAM resistance among Gram-negatives is rising, making dosage selection paramount to preventing surgical site infections. Current guidelines recommend a 3g dose, consisting of 2g ampicillin (AMP) and 1g sulbactam (SUL), every 2h. …”
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    1317. Pharmacokinetics (PK) of Ampicillin-Sulbactam (SAM) during Orthotopic Liver Transplantation (OLT)
  11. 9731
    “…In the design of large cohort multi-site clinical trials, such data are of paramount importance.…”
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    Immediate Sample Fixation Increases Circulating Tumour Cell (CTC) Capture and Preserves Phenotype in Head and Neck Squamous Cell Carcinoma: Towards a Standardised Approach to Microfluidic CTC Biomarker Discovery
  12. 9732
    “…BACKGROUND: With the looming threat of recurrent waves of coronavirus disease-2019 (COVID-19) in the presence of mutated strains, it is of paramount importance to understand the demographic and clinical attributes of COVID-19 related mortalities in each pandemic wave. …”
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    Descriptive Epidemiology of COVID-19 Deaths during the First Wave of Pandemic in India: A Single-center Experience
  13. 9733
    “…However, the treatment length is significantly longer than for the conventional linac, and patient compliance is paramount for the successful completion of the treatment. …”
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    MRI-Guided Online Adaptive Stereotactic Body Radiation Therapy of Liver and Pancreas Tumors on an MR-Linac System
  14. 9734
    “…OBJECTIVES: Preservation of articular cartilage in the setting of acute or chronic injury in the knee is paramount for long-term joint health. Achieving osseous union, minimizing implant related injury, and eliminating the need for reoperation for osteochondral fracture lesions (OCL) and osteochondritis dissecans (OCD) remain a challenge for the orthopedic surgeon. …”
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    Paper 41: Suture-Bridge Fixation of Osteochondral Fractures and Osteochondritis Dissecans in the Knee: Excellent Rates of Early Lesion Stability and Osseous Union
  15. 9735
    “…Further, (+)-catechin, the possible paramount anti-HCC active ingredient in acRoots, helped improve the prognosis of HCC patients by increasing the expression of ESR1 and CAT. …”
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    Systems Network Pharmacology-Based Prediction and Analysis of Potential Targets and Pharmacological Mechanism of Actinidia chinensis Planch. Root Extract for Application in Hepatocellular Carcinoma
  16. 9736
    “…Interventions to address COVID-19 vaccine hesitancy are paramount to reducing the burden of COVID-19. OBJECTIVE: We aimed to evaluate the preliminary efficacy, usability, and acceptability of a chatbot for promoting COVID-19 vaccination and examine the factors associated with COVID-19 vaccine hesitancy. …”
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    Efficacy, Usability, and Acceptability of a Chatbot for Promoting COVID-19 Vaccination in Unvaccinated or Booster-Hesitant Young Adults: Pre-Post Pilot Study
  17. 9737
    “…Maintaining a high degree of suspicion for an androgen-secreting tumor (AST) is paramount when clinical presentation is atypical. OAVS is usually performed when imaging fails to reveal an abnormality, as small ovarian tumors cannot be excluded. …”
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    PMON227 Rare ovarian luteinized fibrothecoma as cause of severe hyperandrogenism in a pre-menopausal woman.
  18. 9738
    “…Nearly half (48%) of providers were unaware of whether their patients owned or had access to a device capable of facilitating a video-based appointment (Kalicki et al, 2021). These issues are paramount given that older adults comprise 15.2% of the U.S. population in 2016. …”
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    Emerging and Evolving Applications of Telemedicine for older adults: A Scoping Review
  19. 9739
    “…Understanding the criticality of complete (i.e., efficient) hand hygiene in healthcare, objectivization of hand hygiene related parameters are paramount, including the formulation of the ABHR. Complete coverage can be achieved with optimal Alcohol-Based Hand Rub (ABHR) provided. …”
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    Evidence-based hand hygiene: Liquid or gel handrub, does it matter?
  20. 9740
    por Gioventu, Alessandra
    Publicado 2023
    “…To select signal candidates, it is of paramount importance to model the main background contributions. …”
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    Tests of Lepton Flavour Universality with semileptonic $D$ and $B$ decays at the LHCb experiment
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