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981por Ormancey, Mélanie, Guillotin, Bruno, Merret, Rémy, Camborde, Laurent, Duboé, Carine, Fabre, Bertrand, Pouzet, Cécile, Impens, Francis, Van Haver, Delphi, Carpentier, Marie-Christine, Clemente, Hélène San, Aguilar, Marielle, Lauressergues, Dominique, Scharff, Lars B., Pichereaux, Carole, Burlet-Schiltz, Odile, Bousquet-Antonelli, Cécile, Gevaert, Kris, Thuleau, Patrice, Plaza, Serge, Combier, Jean-Philippe“…Developing novel, alternative, and safe methods is hence of paramount importance. Here, we show that complementary peptides (cPEPs) from any gene can be designed to target specifically plant coding genes. …”
Publicado 2023
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982“…To harness the benefits of its initiatives, careful dissection of existing health disparities as they relate to precision medicine is of paramount importance. Attempting to address the existing disparities at the early stages of design and implementation of these efforts is the only guarantee of a successful just outcome. …”
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983por Serraino, Riccardo, Owachi, Darius, Byekwaso, Susan Nassaka, Namara, Catherine Misango, Naigambi, Kennedy, Castelli, Francesco, Torti, Carlo“…The emergence of ethical international collaborations is of paramount importance to stimulate these projects and ensure that they are implemented safely and with adequate preparation even and especially during the COVID-19 pandemic.…”
Publicado 2023
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984“…Future research is warranted and paramount for untangling these novel and promising roles for GRK2 and arrestins in metabolism and disease progression.…”
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985“…The Toll-like receptors (TLRs) and interleukin-1 receptors (IL-1R) families are of paramount importance in coordinating the early immune response to pathogens. …”
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986por Hastings, Alan“…Thus, in understanding the interactions of organisms with their physical environment, questions of scale become paramount. These more physical questions illustrate the role scale plays in understanding ecology, and are discussed in chapter two by Akira Okubo.…”
Publicado 1988
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987“…Ensuring the generation of the pulse at a precise moment, typically when the beam passes, is paramount to the correct behaviour of the accelerator. …”
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988por Franchetti, Giuliano, Giovannozzi, Massimo, Hofmann, I, Martini, M, Métral, E, Qiang, J, Ryne, D, Steerenberg, R“…Benchmarking of the simulation codes used for the design of the next generation of high beam power accelerators is of paramount importance due to the very demanding requirements on the level of beam losses. …”
Publicado 2005
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989“…Ensuring the generation of the pulse at a precise moment, typically when the beam passes, is paramount to the correct behaviour of the accelerator. …”
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990“…There is variability in management and outcomes between institutions; however, early and aggressive management to avoid respiratory failure is paramount. In those patients who progress to develop severe respiratory failure, extracorporeal life support (ECLS) can be a life-saving therapy. …”
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991“…Correct diagnosis is paramount for rapid and appropriate treatment.…”
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992“…CONCLUSIONS: Mental disorders in childhood are strongly associated with a longer NEET period in early adulthood, which can be reduced by preventing high school dropout. It is of paramount importance to prevent, detect and treat mental disorders from a young age and prevent persons from dropping out of high school, as it can affect outcomes later in life. …”
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993“…The final themes were: "[Still]birth: Nature of care is paramount", "Real babies: Perfect beauties, monsters and spectres", and "Opportunity of a lifetime lost." …”
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994por Mamede, Adriana P., Santos, Inês P., Batista de Carvalho, Ana L. M., Figueiredo, Paulo, Silva, Maria C., Tavares, Mariana V., Marques, Maria P. M., Batista de Carvalho, Luís A. E.“…Detecting cancer in its early stages is paramount for patients’ prognosis and survival. Hence, the scientific and medical communities are engaged in improving both therapeutic strategies and diagnostic methodologies, beyond prevention. …”
Publicado 2021
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995por Velazquez-Navarro, Jassel A, Loya-Teruel, Edgar, Rios-Gomez, Mariana, Montes-Ramirez, Juan E“…In this case report, we want to highlight the paramount importance of adequate tumor screening in adult patients with acquired FGF23-dependent hypophosphatemia. …”
Publicado 2022
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996“…Developing therapies to reverse viral latency and prevent spread is paramount for the HIV cure agenda. In gay and bisexual men, a major, yet poorly characterized, route of HIV entry is via transport across the colonic epithelial barrier. …”
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997por Sant’Anna da Costa, Ricardo, Di Azevedo, Maria Isabel N., dos Santos Baptista Borges, Ana Luiza, Aymée, Luíza, Martins, Gabriel, Lilenbaum, Walter“…In this context, vaccination of dogs against leptospirosis is of paramount importance for long-term protection against renal carrier status. …”
Publicado 2022
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998por Laurindo, Geovani Marques, Ferraz, Gabriel Araújo e Silva, Damasceno, Flavio Alves, do Nascimento, Joao Antônio Costa, dos Santos, Gabriel Henrique Ribeiro, Ferraz, Patrícia Ferreira Ponciano“…Thus, studies related to the thermal environment and behavior are paramount to assessing animal welfare and optimizing management. …”
Publicado 2022
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999“…The life value of GSH makes for a paramount research field in biology and medicine and may be key against SARS-CoV-2 infection and COVID-19 disease.…”
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1000por Ziegler, Cai-Nicolas“…It rather contemplates an application scenario, namely the gathering of knowledge that appears of paramount importance to organizations, e.g., companies and corporations. …”
Publicado 2012
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