“…This article explains the paramount importance of children's hospitals for providing safe and effective multidisciplinary pediatric care.…”
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“…Our approach shows that the correct choice of the individual units together with their rational assembly are of paramount importance in the development of complex nanostructures with advanced functionalities.…”
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“…A thorough understanding of eicosanoid signaling is paramount for understanding the underlying mechanisms and developing potential treatments for AD. …”
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“…This large monument is paramount for the archaeological exploration of the early Scythian period in the Eurasian steppes, but environmental parameters make research on site difficult and require the application of a diversity of methods. …”
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“…The short duration of reversals make precise temporal records of past magnetic field behavior paramount to understanding the processes that produce them. …”
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“…Tolerance of therapy is paramount, and uncontrolled nausea and vomiting may limit use. …”
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“…Prompt recognition and treatment of this injury are of paramount importance for a good long-term outcome. …”
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“…The correct grading and staging of these lesions are of paramount significance, due its impact on patient management and prognosis.…”
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“…Understanding adolescent growth and developmental characteristics is paramount to appropriate care, prevention, and treatment of physeal injuries that may occur from repetitive overuse and avoid surgery in these young athletes when possible.…”
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“…Understanding the aetiology with early diagnosis and appropriate management of delayed hardware migration are paramount in reducing patient morbidity and potential life-threatening otolaryngologic complications.…”
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“…Moreover, a better understanding of the mechanisms involved in the platelet–tumor axis represents a paramount aspect for optimizing both current tumor treatment and development of new therapeutic strategies against HCC.…”
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“…Meaningful activities as well as autonomous decision-making concerning one’s living place seem of paramount importance for residents’ better perception of their QoL. …”
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“…To improve the diagnostic accuracy of electroencephalography (EEG) criteria for nonconvulsive status epilepticus (NCSE), external validation of the recently proposed Salzburg criteria is paramount. We performed an external, retrospective, diagnostic accuracy study of the Salzburg criteria, using EEG recordings from patients with and without a clinical suspicion of having NCSE. …”
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“…These properties establish divacancies as strong candidates for quantum communication and hybrid system applications, where simultaneous control over optical and spin degrees of freedom is paramount.…”
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“…The usage of this increased pool of origins, contributing to the maintenance of DNA replication, seems to be of paramount importance for the survival of this parasite that affects million people around the world.…”
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“…Development of high performances gas sensors to monitor and detect the volatile organic compound triethylamine is of paramount importance for health and environmental protection. …”
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“…In general, the identification of patients at risk of early ovarian failure, for benign gynecological disease or based on known genetic causes or familiarity, is of paramount importance in order to apply fertility preservation techniques before the complete depletion of ovarian reserve.…”
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“…Extensive characterization of the effective PRs revealed inhibition of the proteasome and elevation of GLA gene expression as paramount effects. Further analysis of transcriptional patterns of the PRs exposed a variety of genes involved in proteostasis as potential modulators. …”
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“…The pharmacological treatments associated with these algorithms suppress inflammation through a variety of mechanisms and are paramount to improving the safety profile of CAR-based therapies. …”
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“…Instant and adequate handling of misfolded or otherwise aberrant proteins is of paramount importance for maintaining protein homeostasis in cells. …”
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