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  1. 5341
    “…It also produces small-molecule virulence factors that interact with the respiratory chain, including the poison cyanide. Previous studies had indicated a role for cyanide in activating expression of an “orphan” terminal oxidase subunit gene called ccoN4 and that the product contributes to P. aeruginosa cyanide resistance, fitness in biofilms, and virulence–but the mechanisms underlying this process had not been elucidated. …”
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    Cyanide-dependent control of terminal oxidase hybridization by Pseudomonas aeruginosa MpaR
  2. 5342
    “…While Mirin sensitises DT40 MRE11(+/)(−) cells to the Top1 poison SN-38, it does not sensitise nuclease-dead MRE11 cells to this compound confirming that Mirin specifically inhibits Mre11 nuclease activity. …”
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    Selective Killing of BRCA2-Deficient Ovarian Cancer Cells via MRE11 Blockade
  3. 5343
    “…Furthermore, the extracts were tested for their antifungal ability using the poison food technique. For measuring antioxidant activity, the 1,1-diphenyl-2-picryl-hydrazyl (DPPH) test was used. …”
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    Exploration and Evaluation of Secondary Metabolites from Trichoderma harzianum: GC-MS Analysis, Phytochemical Profiling, Antifungal and Antioxidant Activity Assessment
  4. 5344
    “…CONCLUSION: Our study demonstrates the application of ML in the prediction of DPH poisoning.…”
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    The value of machine learning for prognosis prediction of diphenhydramine exposure: National analysis of 50,000 patients in the United States
  5. 5345
    “…RESULTS: The average age of the patients by means of suicide attempt was 40.5 years for “prescription drugs,” 30.2 years for “over‐the‐counter drugs,” and 63.5 years for “pesticide/poison.” For each means of suicide attempt, there was a significant difference in age among patients with suicide attempts using “prescription drugs,” “over‐the‐counter drugs” and “pesticides/poisons.” …”
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    Effects of age on suicide attempts by medication in patients transferred to the emergency rooms of two advanced medical centers: A retrospective chart review of the DJ project
  6. 5346
    “…In this study, we used 50 mg/kg/d BPS as a poison and PUE as an intervention for model mice for 42 d. …”
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    Puerarin Prevents Bisphenol S Induced Lipid Accumulation by Reducing Liver Lipid Synthesis and Promoting Lipid Metabolism in C57BL/6J Mice
  7. 5347
    “…These include antisense nucleotides directed against the nonproductive transcript of SCN1A with the poison exon 20N and against an inhibitory noncoding antisense RNA of SCN1A. …”
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    Targeted Molecular Strategies for Genetic Neurodevelopmental Disorders: Emerging Lessons from Dravet Syndrome
  8. 5348
    “…This role as an “essential poison” is related to the function of c-di-AMP in the control of potassium homeostasis. …”
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    The many roles of cyclic di-AMP to control the physiology of Bacillus subtilis
  9. 5349
    “…[NiFe]-hydrogenases are a promising alternative to the platinum-based catalysts that currently predominate in fuel cells due to the abundance of nickel and iron, and the resistance of some family members to inhibition by gases, including carbon monoxide, which rapidly poison platinum-based catalysts. However, the majority of characterised [NiFe]-hydrogenases are inhibited by oxygen (O(2)), limiting their activity and stability. …”
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    Developing high-affinity, oxygen-insensitive [NiFe]-hydrogenases as biocatalysts for energy conversion
  10. 5350
    “…The enzyme activity extracted from CALU3 is sensitive to inhibition by the topoisomerase II poison etoposide. Topoisomerase II beta expression was observed in three lung cancer cell lines including CALU3 and was confined to the nucleoli. …”
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    Expression of topoisomerase II alpha and beta in an adenocarcinoma cell line carrying amplified topoisomerase II alpha and retinoic acid receptor alpha genes.
  11. 5351
    por Meltzer, S. J.
    Publicado 1911
    “…The experiments with strychnin prove positively that the paralysing effect of this poison is due to its direct action upon the nerve cells of the cord, and not, as Verworn assumes, to a paralysing action upon the heart. …”
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    THE DISTRIBUTION OF SOLUTIONS IN CARDIECTOMIZED FROGS
  12. 5352
    por Duval, Charles W., Hibbard, R. J.
    Publicado 1927
    “…The liberation of the poison in vitro occurs as the natural result of autolysis while in vivo it is produced through specific action of bacteriolysin.…”
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    NATURE OF THE TOXIC MOIETY OF STREPTOCOCCUS SCARLATINÆ
  13. 5353
    “…Protease activation was demonstrated in specimens of human skin under the influence of a poison ivy extract or croton oil added in vitro. Urinary protease activity of guinea pigs increased significantly during the first hours of anaphylactic shock and very markedly in peptone shock. …”
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    FURTHER STUDIES ON THE ROLE OF PROTEASES IN THE ALLERGIC REACTION
  14. 5354
    por Gould, Bernard S., Tytell, Alfred A.
    Publicado 1941
    “…Low concentrations of iodoacetate or fluoride selectively poison the exogenous mechanism but do not affect the endogenous mechanism. …”
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    STUDIES IN THE PHYSIOLOGY OF FUSARIA. THE RESPIRATORY AND FERMENTATIVE MECHANISMS
  15. 5355
    “…Data on exposures to lindane were obtained from records of the California Poison Control System. We assessed the impact on clinical practice via a survey of 400 pediatricians RESULTS: Wastewater treatment plant monitoring showed that lindane declined in California after the ban. …”
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    Outcomes of the California Ban on Pharmaceutical Lindane: Clinical and Ecologic Impacts
  16. 5356
    “…Accumulation of labelled chloramphenicol was monitored in the presence of an energy poison to determine the involvement of active efflux on the antibiotic intracellular concentrations. …”
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    Identification and Evolution of Drug Efflux Pump in Clinical Enterobacter aerogenes Strains Isolated in 1995 and 2003
  17. 5357
    “…By contrast, 2-phenyl-3-nitroso-imidazo[1,2-a]pyrimidine acted as a DNA poison, causing damage to the nuclear DNA and inducing mutagenesis. …”
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    Chemical–Genetic Profiling of Imidazo[1,2-a]pyridines and -Pyrimidines Reveals Target Pathways Conserved between Yeast and Human Cells
  18. 5358
    “…Using a pharmacogenetic approach, we find that flies sense food containing this poison by the DmX receptor. DmXR is an insect orphan G-protein–coupled receptor that has partially diverged in its ligand binding pocket from the metabotropic glutamate receptor family. …”
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    Plant Insecticide L-Canavanine Repels Drosophila via the Insect Orphan GPCR DmX
  19. 5359
    “…BACKGROUND: Botulinum neurotoxin (BoNT) is the most potent poison known to mankind. Currently no antidote is available to rescue poisoned synapses. …”
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    An efficient drug delivery vehicle for botulism countermeasure
  20. 5360
    “…This assumption is based on the precept that “the dose makes the poison”: higher doses will cause greater effects. …”
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    A Clash of Old and New Scientific Concepts in Toxicity, with Important Implications for Public Health
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