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  1. 5381
    “…This information could suggest that truncating proteins may be compensated by the normal allele and that missense mutations may act as poison peptides.…”
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    Stop-Gain Mutations in PKP2 Are Associated with a Later Age of Onset of Arrhythmogenic Right Ventricular Cardiomyopathy
  2. 5382
    “…Methanol (MeOH) is considered to be a poison in humans because of the alcohol dehydrogenase (ADH)-mediated conversion of MeOH to formaldehyde (FA), which is toxic. …”
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    Dietary Methanol Regulates Human Gene Activity
  3. 5383
    “…As revealed by many cases worldwide, such a marketing strategy led to unintentional self-poisonings and deaths. FIPs therefore constitute a very serious health and public policy issue. …”
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    Why People Drink Shampoo? Food Imitating Products Are Fooling Brains and Endangering Consumers for Marketing Purposes
  4. 5384
    “…Different types of topoisomerases occur in human cells and several poisons of topoisomerase I and II are widely used clinically. …”
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    Novel DNA Topoisomerase IIα Inhibitors from Combined Ligand- and Structure-Based Virtual Screening
  5. 5385
    por Jovanović, Boris
    Publicado 2015
    “…Nevertheless, because dose makes the poison, the literature provides a valuable source for understanding potential TiO(2) toxicity after oral ingestion. …”
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    Critical Review of Public Health Regulations of Titanium Dioxide, a Human Food Additive
  6. 5386
    “…OBJECTIVE: Lead (Pb) is a long-known poison of environment and industrial origin. Its prolonged exposure affects cellular material and alters cellular genetics and produces oxidative damages. …”
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    α-tocopherol supplementation prevents lead acetate and hypoxia-induced hepatic dysfunction
  7. 5387
    “…Thus, olive metabolites appear to act as topoisomerase II poisons in complex formulations intended for human dietary consumption.…”
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    Effects of Olive Metabolites on DNA Cleavage Mediated by Human Type II Topoisomerases
  8. 5388
    “…Moreover, WABS cell lines, and several cancer cell lines with cohesion defects, display a highly increased response to a new cell-permeable APC/C inhibitor, apcin, but not to the spindle poison paclitaxel. Synthetic lethality of APC/C inhibition and cohesion defects strictly depends on a functional mitotic spindle checkpoint as well as on intact microtubule pulling forces. …”
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    Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function
  9. 5389
    “…The mRNA level of AccDpp was higher in the poison gland and midgut than other tissues. Furthermore, the transcription of AccDpp could be repressed by 4°C and UV, but induced by other treatments, according to our qRT-PCR analysis. …”
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    Characterization of a Decapentapletic Gene (AccDpp) from Apis cerana cerana and Its Possible Involvement in Development and Response to Oxidative Stress
  10. 5390
    “…Wasp venom primarily comprises peptides that are responsible for most of the biological activities in this poison. Here, a novel peptide Polydim-I, from Polybia dimorpha Neotropical wasp, was explored as an antimycobacterial agent. …”
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    Antimycobacterial Activity of a New Peptide Polydim-I Isolated from Neotropical Social Wasp Polybia dimorpha
  11. 5391
    “…Proteins transcribed from hub genes and their ligands selected by search ensemble approach algorithm were subjected to molecular docking studies, as well as 20 ns Molecular Dynamics (MD) using a Molecular Mechanic Poison/Boltzman Surface Area (MMPBSA) protocol. Our results bring a new approach to Valeriana officinalis extract, and suggest that hesperidin, and probably linarin are able to relieve effects of oxidative stress during ATP depletion due to its ability to binding SUR1. …”
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    SUR1 Receptor Interaction with Hesperidin and Linarin Predicts Possible Mechanisms of Action of Valeriana officinalis in Parkinson
  12. 5392
    por Bochner, Rosany
    Publicado 2016
    “…The current study presents a descriptive chronological survey of the articles published by Césaire Auguste Phisalix and Albert Calmette on snake poison, with the aim of shedding a light on the areas of research and reasoning followed by these scientists, leading up to their simultaneous discovery of antivenom serotherapy in 1894. …”
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    Paths to the discovery of antivenom serotherapy in France
  13. 5393
    “…Aims: Carbon monoxide is a respiratory poison and gaseous signaling molecule. Although CO-releasing molecules (CORMs) deliver CO with temporal and spatial specificity in mammals, and are proven antimicrobial agents, we do not understand the modes of CO toxicity. …”
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    Carbon Monoxide Gas Is Not Inert, but Global, in Its Consequences for Bacterial Gene Expression, Iron Acquisition, and Antibiotic Resistance
  14. 5394
    “…Consumption of plant poison and tablet overdose was higher among women. …”
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    Profile of deliberate self-harm patients presenting to Emergency Department: A retrospective study
  15. 5395
    “…We show that high USP9X/XIAP expression is associated with shorter event‐free survival in patients treated with spindle poison‐containing chemotherapy. Accordingly, aggressive B‐cell lymphoma lines with USP9X and associated XIAP overexpression exhibit increased chemoresistance, reversed by specific inhibition of either USP9X or XIAP. …”
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    USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B‐cell lymphoma
  16. 5396
    “…We recorded 2 deaths by rat poison poisoning. All patients were advised in writing after leaving to follow up with a psychological treatment. …”
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    Epidemiological aspects of suicide attempts among Moroccan children
  17. 5397
    “…Human intoxication with the seafood poison ciguatoxin, a dinoflagellate polyether that activates voltage-gated sodium channels (Na(V)), causes ciguatera, a disease characterised by gastrointestinal and neurological disturbances. …”
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    Multiple sodium channel isoforms mediate the pathological effects of Pacific ciguatoxin-1
  18. 5398
    “…A retrospective study was conducted from July 2014 to March 2015 regarding all therapeutic drug-monitoring requests sent to the Laboratory of Poison Control and Pharmacovigilance Centre of Morocco. 142 patients diagnosed with active tuberculosis were included in study. …”
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    First line anti-tuberculosis induced hepatotoxicity: incidence and risk factors
  19. 5399
    “…METHODS: A descriptive cross-sectional design was used to collect data from electronic database of a regional Poison Control Center during one year. Data were analyzed by means of descriptive non-parametric statistics and association tests. …”
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    TOXIC EXPOSURES IN CHILDREN INVOLVING LEGALLY AND ILLEGALLY COMMERCIALIZED HOUSEHOLD SANITIZERS
  20. 5400
    “…Conventionally, the larger the dose, the greater the response, following the dogma “the dose makes the poison”. Many endocrine disrupting chemicals, including bisphenol-A (BPA), induce non-monotonic dose response (NMDR) relationships, which are unconventional and have tremendous implications in risk assessment. …”
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    Molecular mechanisms involved in the non-monotonic effect of bisphenol-a on Ca(2+) entry in mouse pancreatic β-cells
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