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Toxicología
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Hongos venenosos
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3
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3
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5381por Alcalde, Mireia, Campuzano, Oscar, Berne, Paola, García-Pavía, Pablo, Doltra, Ada, Arbelo, Elena, Sarquella-Brugada, Georgia, Iglesias, Anna, Alonso-Pulpon, Luis, Brugada, Josep, Brugada, Ramon“…This information could suggest that truncating proteins may be compensated by the normal allele and that missense mutations may act as poison peptides.…”
Publicado 2014
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5382por Shindyapina, Anastasia V., Petrunia, Igor V., Komarova, Tatiana V., Sheshukova, Ekaterina V., Kosorukov, Vyacheslav S., Kiryanov, Gleb I., Dorokhov, Yuri L.“…Methanol (MeOH) is considered to be a poison in humans because of the alcohol dehydrogenase (ADH)-mediated conversion of MeOH to formaldehyde (FA), which is toxic. …”
Publicado 2014
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5383por Basso, Frédéric, Robert-Demontrond, Philippe, Hayek, Maryvonne, Anton, Jean-Luc, Nazarian, Bruno, Roth, Muriel, Oullier, Olivier“…As revealed by many cases worldwide, such a marketing strategy led to unintentional self-poisonings and deaths. FIPs therefore constitute a very serious health and public policy issue. …”
Publicado 2014
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5384por Drwal, Malgorzata N., Marinello, Jessica, Manzo, Stefano G., Wakelin, Laurence P. G., Capranico, Giovanni, Griffith, Renate“…Different types of topoisomerases occur in human cells and several poisons of topoisomerase I and II are widely used clinically. …”
Publicado 2014
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5385por Jovanović, Boris“…Nevertheless, because dose makes the poison, the literature provides a valuable source for understanding potential TiO(2) toxicity after oral ingestion. …”
Publicado 2015
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5386por Das, Kusal K., Jargar, Jameel G., Saha, Sikha, Yendigeri, Saeed M., Singh, Shashi Bala“…OBJECTIVE: Lead (Pb) is a long-known poison of environment and industrial origin. Its prolonged exposure affects cellular material and alters cellular genetics and produces oxidative damages. …”
Publicado 2015
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5387por Vann, Kendra R., Sedgeman, Carl A., Gopas, Jacob, Golan-Goldhirsh, Avi, Osheroff, Neil“…Thus, olive metabolites appear to act as topoisomerase II poisons in complex formulations intended for human dietary consumption.…”
Publicado 2015
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5388por de Lange, Job, Faramarz, Atiq, Oostra, Anneke B., de Menezes, Renee X., van der Meulen, Ida H., Rooimans, Martin A., Rockx, Davy A., Brakenhoff, Ruud H., van Beusechem, Victor W., King, Randall W., de Winter, Johan P., Wolthuis, Rob M. F.“…Moreover, WABS cell lines, and several cancer cell lines with cohesion defects, display a highly increased response to a new cell-permeable APC/C inhibitor, apcin, but not to the spindle poison paclitaxel. Synthetic lethality of APC/C inhibition and cohesion defects strictly depends on a functional mitotic spindle checkpoint as well as on intact microtubule pulling forces. …”
Publicado 2015
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5389por Li, Guilin, Zhao, Hang, Wang, Hongfang, Guo, Xulei, Guo, Xingqi, Sun, Qinghua, Xu, Baohua“…The mRNA level of AccDpp was higher in the poison gland and midgut than other tissues. Furthermore, the transcription of AccDpp could be repressed by 4°C and UV, but induced by other treatments, according to our qRT-PCR analysis. …”
Publicado 2016
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5390por das Neves, Rogerio Coutinho, Trentini, Monalisa Martins, de Castro e Silva, Juliana, Simon, Karina Smidt, Bocca, Anamelia Lorenzetti, Silva, Luciano Paulino, Mortari, Marcia Renata, Kipnis, Andre, Junqueira-Kipnis, Ana Paula“…Wasp venom primarily comprises peptides that are responsible for most of the biological activities in this poison. Here, a novel peptide Polydim-I, from Polybia dimorpha Neotropical wasp, was explored as an antimycobacterial agent. …”
Publicado 2016
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5391por Santos, Gesivaldo, Giraldez-Alvarez, Lisandro Diego, Ávila-Rodriguez, Marco, Capani, Francisco, Galembeck, Eduardo, Neto, Aristóteles Gôes, Barreto, George E., Andrade, Bruno“…Proteins transcribed from hub genes and their ligands selected by search ensemble approach algorithm were subjected to molecular docking studies, as well as 20 ns Molecular Dynamics (MD) using a Molecular Mechanic Poison/Boltzman Surface Area (MMPBSA) protocol. Our results bring a new approach to Valeriana officinalis extract, and suggest that hesperidin, and probably linarin are able to relieve effects of oxidative stress during ATP depletion due to its ability to binding SUR1. …”
Publicado 2016
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5392por Bochner, Rosany“…The current study presents a descriptive chronological survey of the articles published by Césaire Auguste Phisalix and Albert Calmette on snake poison, with the aim of shedding a light on the areas of research and reasoning followed by these scientists, leading up to their simultaneous discovery of antivenom serotherapy in 1894. …”
Publicado 2016
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5393por Wareham, Lauren K., Begg, Ronald, Jesse, Helen E., van Beilen, Johan W.A., Ali, Salar, Svistunenko, Dimitri, McLean, Samantha, Hellingwerf, Klaas J., Sanguinetti, Guido, Poole, Robert K.“…Aims: Carbon monoxide is a respiratory poison and gaseous signaling molecule. Although CO-releasing molecules (CORMs) deliver CO with temporal and spatial specificity in mammals, and are proven antimicrobial agents, we do not understand the modes of CO toxicity. …”
Publicado 2016
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5394por Jegaraj, Moses Kirubairaj Amos, Mitra, Shubhanker, Kumar, Sathish, Selva, Bagyalakshmi, Pushparaj, Manimaran, Yadav, Bijesh, Prabhakar, Abhilash Kundavaram Paul, Reginald, Alex“…Consumption of plant poison and tablet overdose was higher among women. …”
Publicado 2016
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5395por Engel, Katharina, Rudelius, Martina, Slawska, Jolanta, Jacobs, Laura, Ahangarian Abhari, Behnaz, Altmann, Bettina, Kurutz, Julia, Rathakrishnan, Abirami, Fernández‐Sáiz, Vanesa, Brunner, Andrä, Targosz, Bianca‐Sabrina, Loewecke, Felicia, Gloeckner, Christian Johannes, Ueffing, Marius, Fulda, Simone, Pfreundschuh, Michael, Trümper, Lorenz, Klapper, Wolfram, Keller, Ulrich, Jost, Philipp J, Rosenwald, Andreas, Peschel, Christian, Bassermann, Florian“…We show that high USP9X/XIAP expression is associated with shorter event‐free survival in patients treated with spindle poison‐containing chemotherapy. Accordingly, aggressive B‐cell lymphoma lines with USP9X and associated XIAP overexpression exhibit increased chemoresistance, reversed by specific inhibition of either USP9X or XIAP. …”
Publicado 2016
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5396por Mekaoui, Nour, Karboubi, Lamiae, Ouadghiri, Fatima Zahra, Dakhama, Badr Sououd Benjelloun“…We recorded 2 deaths by rat poison poisoning. All patients were advised in writing after leaving to follow up with a psychological treatment. …”
Publicado 2016
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5397por Inserra, Marco C., Israel, Mathilde R., Caldwell, Ashlee, Castro, Joel, Deuis, Jennifer R., Harrington, Andrea M., Keramidas, Angelo, Garcia-Caraballo, Sonia, Maddern, Jessica, Erickson, Andelain, Grundy, Luke, Rychkov, Grigori Y., Zimmermann, Katharina, Lewis, Richard J., Brierley, Stuart M., Vetter, Irina“…Human intoxication with the seafood poison ciguatoxin, a dinoflagellate polyether that activates voltage-gated sodium channels (Na(V)), causes ciguatera, a disease characterised by gastrointestinal and neurological disturbances. …”
Publicado 2017
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5398por Bouazzi, Omaima El, Hammi, Sanaa, Bourkadi, Jamal Eddine, Tebaa, Amina, Tanani, Driss Soussi, Soulaymani-Bencheikh, Rachida, Badrane, Narjis, Bengueddour, Rachid“…A retrospective study was conducted from July 2014 to March 2015 regarding all therapeutic drug-monitoring requests sent to the Laboratory of Poison Control and Pharmacovigilance Centre of Morocco. 142 patients diagnosed with active tuberculosis were included in study. …”
Publicado 2016
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5399por Campos, Alessandra Marcuz de Souza, Bucaretchi, Fábio, Fernandes, Luciane Cristina Rodrigues, Fernandes, Carla Borrasca, de Capitani, Eduardo Mello, Beck, Ana Raquel Medeiros“…METHODS: A descriptive cross-sectional design was used to collect data from electronic database of a regional Poison Control Center during one year. Data were analyzed by means of descriptive non-parametric statistics and association tests. …”
Publicado 2017
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5400por Villar-Pazos, Sabrina, Martinez-Pinna, Juan, Castellano-Muñoz, Manuel, Alonso-Magdalena, Paloma, Marroqui, Laura, Quesada, Ivan, Gustafsson, Jan-Ake, Nadal, Angel“…Conventionally, the larger the dose, the greater the response, following the dogma “the dose makes the poison”. Many endocrine disrupting chemicals, including bisphenol-A (BPA), induce non-monotonic dose response (NMDR) relationships, which are unconventional and have tremendous implications in risk assessment. …”
Publicado 2017
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