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Toxicología
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5581por Witayavanitkul, Namthip, Ait Mou, Younss, Kuster, Diederik W. D., Khairallah, Ramzi J., Sarkey, Jason, Govindan, Suresh, Chen, Xin, Ge, Ying, Rajan, Sudarsan, Wieczorek, David F., Irving, Thomas, Westfall, Margaret V., de Tombe, Pieter P., Sadayappan, Sakthivel“…Decreased cardiac function post-MI may result, in part, from the ability of hC0C1f to bind actin and α-tropomyosin, suggesting that cleaved C0-C1f could act as a poison polypeptide and disrupt the interaction of native cardiac myosin-binding protein C with the thin filament.…”
Publicado 2014
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5582por Achana, Felix A, Cooper, Nicola J, Bujkiewicz, Sylwia, Hubbard, Stephanie J, Kendrick, Denise, Jones, David R, Sutton, Alex J“…We apply the methods to binary outcome data from a systematic review evaluating the effectiveness of nine home safety interventions on uptake of three poisoning prevention practices (safe storage of medicines, safe storage of other household products, and possession of poison centre control telephone number) in households with children. …”
Publicado 2014
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5583“…DESIGN: Primary murine colon epithelial cells were repetitively exposed to Enterococcus faecalis-infected macrophages, or purified trans-4-hydroxy-2-nonenal (4-HNE)—an endogenous mutagen and spindle poison produced by macrophages. CIN, gene expression, growth as allografts in immunodeficient mice were examined for clones and expression of markers confirmed using interleukin (IL) 10 knockout mice colonised by E. faecalis. …”
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5584por Uitdehaag, Joost C. M., de Roos, Jeroen A. D. M., van Doornmalen, Antoon M., Prinsen, Martine B. W., Spijkers-Hagelstein, Jill A. P., de Vetter, Judith R. F., de Man, Jos, Buijsman, Rogier C., Zaman, Guido J. R.“…The EGFR/ERBB2 inhibitor neratinib acted synergistically with the spindle poison docetaxel and with the Aurora kinase inhibitor GSK-1070916 in cell lines with MYC amplification. …”
Publicado 2015
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5585Epidemiology of non-fatal injuries among Egyptian children: a community-based cross-sectional surveypor Halawa, Eman Fawzy, Barakat, Abeer, Rizk, Hoda Ibrahim Ibrahim, Moawad, Eman Mohamed Ibraheim“…The five main causes of injuries were wounds (30.6 %), fractures (28.7 %), burns (20.3 %), swallowing a foreign body (8.4 %) and accidentally ingesting a poison (7.8 %). Injuries from drowning (n = 27), animal bites (n = 22) and sunstroke (n = 20) mostly occurred in rural children, accounting for 65 %, 54.4 % and 52 %, respectively, of all injuries in rural children. …”
Publicado 2015
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5586por Aguilera, Pablo, Garrido, Marcela, Lessard, Eli, Swanson, Julian, Mallon, William K., Saldias, Fernando, Basaure, Carlos, Lara, Barbara, Swadron, Stuart P.“…INTRODUCTION: While a nationwide poison control registry exists in Chile, reporting to the center is sporadic and happens at the discretion of the treating physician or by patients’ self-report. …”
Publicado 2016
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5587por Miliano, Cristina, Serpelloni, Giovanni, Rimondo, Claudia, Mereu, Maddalena, Marti, Matteo, De Luca, Maria Antonietta“…The use of NPS, mainly consumed along with other drugs of abuse and/or alcohol, has resulted in a significantly growing number of mortality and emergency admissions for overdoses, as reported by several poison centers from all over the world. The fact that the number of NPS have more than doubled over the last 10 years, is a critical challenge to governments, the scientific community, and civil society [EMCDDA (European Drug Report), 2014; UNODC, 2014b; Trends and developments]. …”
Publicado 2016
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5588por Millichap, John J., Park, Kristen L., Tsuchida, Tammy, Ben-Zeev, Bruria, Carmant, Lionel, Flamini, Robert, Joshi, Nishtha, Levisohn, Paul M., Marsh, Eric, Nangia, Srishti, Narayanan, Vinodh, Ortiz-Gonzalez, Xilma R., Patterson, Marc C., Pearl, Phillip L., Porter, Brenda, Ramsey, Keri, McGinnis, Emily L., Taglialatela, Maurizio, Tracy, Molly, Tran, Baouyen, Venkatesan, Charu, Weckhuysen, Sarah, Cooper, Edward C.“…They were clustered in 4 protein subdomains predicted to poison tetrameric channel functions. EZO use (assessed by the treating physicians and parents) was associated with improvement in seizures and/or development in 3 of the 4 treated before 6 months of age, and 2 of the 7 treated later; no serious side effects were observed. …”
Publicado 2016
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5589por López-Gallardo, Ester, Llobet, Laura, Emperador, Sonia, Montoya, Julio, Ruiz-Pesini, Eduardo“…Indeed, the inhibition of a particular enzyme by a poison could imitate the biochemical effects of pathological mutations in that enzyme. …”
Publicado 2016
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5590por Iwanicki, Janetta L., Severtson, S. Geoff, McDaniel, Heather, Rosenblum, Andrew, Fong, Chunki, Cicero, Theodore J., Ellis, Matthew S., Kurtz, Steven P., Buttram, Mance E., Dart, Richard C.“…RESULTS: From 2009 to 2015, IR opioids were prescribed at a rate 12 to 16 times higher than ER. In the Poison Center Program, population-adjusted rates of Intentional Abuse for IR were 4.6 fold higher than ER opioids (p<0.001). …”
Publicado 2016
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5591“…Common diagnoses provided by TH included liver problem, abscess, witchcraft, poison, hernia, side pain, mushroom in the belly and toothache. …”
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5592por Peterson, Joseph E., Warnock, Jonathan P., Eberhart, Shawn L., Clawson, Steven R., Noto, Christopher R.“…Since excavation began in the 1920s, numerous hypotheses have been put forward to explain the taphonomy of CLDQ, including a predator trap, a drought assemblage, and a poison spring. In an effort to reconcile the various interpretations of the quarry and reach a consensus on the depositional history of CLDQ, new data is required to develop a robust taphonomic framework congruent with all available data. …”
Publicado 2017
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5593por Geith, Stefanie, Renner, Bertold, Rabe, Christian, Stenzel, Jochen, Eyer, Florian“…BACKGROUND: Inquiries relating to ibuprofen overdose have more than tripled in the last ten years in our poison control center. Although the vast majority of cases have a benign clinical course, there are few severe or even fatal cases present with refractory circulatory failure. …”
Publicado 2017
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5594por Hanuscin, Chris, Zahmatkesh, Golara, Shirazi, Anaheed, Pan, Deyu, Teklehaimanot, Senait, Bazargan-Hejazi, Shahrzad“…Analyses of the SIH methods revealed that Blacks were less likely to self-poison [Odds Ratio (OR): 0.78] compared to Whites, whereas individuals with psychiatric disorders or substance abuse carried 2.5 and 2.0-fold higher risk, respectively. …”
Publicado 2018
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5595por Settimi, Laura, Giordano, Felice, Lauria, Laura, Celentano, Anna, Sesana, Fabrizio, Davanzo, Franca“…METHODS: Analyses of a series of patients aged <5 years and exposed to laundry detergents between September 2010 and June 2015, identified by the National Poison Control in Milan. RESULTS: In comparison with patients exposed to traditional laundry detergents (n=1150), a higher proportion of those exposed to pods (n=1649) were managed in hospital (68% vs 42%), had clinical effects (75% vs 22%) and moderate/high severity outcomes (13% vs <1%). …”
Publicado 2018
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5596por Walker, Caroline, Allamneni, Chaitanya, Orr, Jordan, Yun, Huifeng, Fitzmorris, Paul, Xie, Fenglong, Malik, Talha A.“…Demographics and hospitalization rates were collected. Poison regression models estimated incidence rate ratios (IRR) for CD-related hospitalizations. …”
Publicado 2018
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5597“…The in vitro effects of fungicides on the radial growth of the pathogen were evaluated through the poison food method and were compared with potent antagonistic fungi. …”
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5598por Valdes, Gilmer, Chan, Maria F., Lim, Seng Boh, Scheuermann, Ryan, Deasy, Joseph O., Solberg, Timothy D.“…Plans were characterized by 90 different complexity metrics. A weighted poison regression with Lasso regularization was trained to predict passing rates using the complexity metrics as input. …”
Publicado 2017
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5599“…According to the US Animal Poison Control Center, cannabis intoxication mostly affects dogs (96%). …”
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5600por Tongpoo, Achara, Sriapha, Charuwan, Pradoo, Aimon, Udomsubpayakul, Umaporn, Srisuma, Sahaphume, Wananukul, Winai, Trakulsrichai, Satariya“…MATERIALS AND METHODS: The data of krait envenomation cases that occurred during a 9-year period were obtained from the Ramathibodi Poison Center Toxic Exposure Surveillance System and retrospectively analyzed. …”
Publicado 2018
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