“…Detection methods are needed to determine the occurrence of AMAs in mushroom species suspected in mushroom poisonings. In this manuscript, we report the generation of novel monoclonal antibodies (mAbs, AMA9G3 and AMA9C12) and the development of a competitive, enzyme-linked immunosorbent assay (cELISA) that is sensitive at 1 ng mL(−1) and shows selectivity for α-amanitin (α-AMA) and γ-amanitin (γ-AMA), and less for β-amanitin (β-AMA). …”
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“…Tetanus and botulinum neurotoxins are the most poisonous substances known, so much so as to be considered for a possible terrorist use. …”
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“…The use of different heterogeneity tests, such as hot filtration test and poisoning experiments, has provided a deep insight into the reaction mechanism and has confirmed that the reaction occurs in the homogeneous phase following a “release and catch” mechanism. …”
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“…Chaperones like acid and heat shock proteins provide protection from high temperatures, metabolic poisons, and other stressful conditions. Several natural and artificial proteins are components of vaccines, a key strategy to control fatal diseases, lacking empirical treatment. …”
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“…Specifically, this review focuses on diseases prevalent in sub-Saharan Africa and south Asia: melioidosis, infant and maternal mortality, schistosomiasis, and heavy metal and pesticide poisoning. Our aim with this review is to identify problems facing the world that require the attention of the medical device community and provide recommendations for research directions for groups interested in this field.…”
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“…Metformin-associated lactic acidosis is a rare side effect in metformin poisoning. There is conflicting data about mortality rates changing from 3% to 83%. …”
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“…The electrosynthesized well-ordered mesoporous Ni-rich Ni-Pt deposits exhibit excellent electrocatalytic performance for methanol oxidation in alkaline conditions, improved stability and durability after 1000 cycles, and minimal CO poisoning.…”
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“…Progress in understanding how bacteria avoid Cu poisoning while maintaining a certain Cu quota for cell proliferation is of particular importance for microbial pathogens because Cu is utilized by the host immune system for attenuating pathogen survival in host cells.…”
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“…Drinking liquids with high alcohol concentration, especially methanol, causes poisoning, and the use of colognes with high alcohol concentration causes various skin conditions and respiratory diseases. …”
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“…This work mainly summarizes the history, synthesis, pharmacology, toxicology, structure–activity relationship, metabolism, clinical process and health risks, poisoning and death, forensic toxicology, and legal status of α-PVP. …”
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“…Herein, we report a rare case who was admitted to the emergency room with decreased consciousness resembling methadone poisoning. Clinical work-up showed a temporoparietal mass on radiological investigation. …”
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“…Clostridium perfringens α toxin (CPA) is an important virulence factor that causes livestock hemorrhagic enteritis and food poisoning by contaminated meat products. In this study, the nano-silica microspheres combined with smartphone image processing technology was developed to realize real-time CPA detection. …”
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“…Together, our data demonstrate that Bort, a compound structurally unrelated to tubulin poisons, affects the tubulin cytoskeleton in sensory neurons in vitro, in vivo, and in human tissue, indicating that the pathogenic mechanisms of seemingly unrelated CIPN drugs may converge on tubulin damage. …”
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“…Inhibition of gyrase activity is achieved by competitive inhibitors that interfere with ATP- or DNA-binding, or by gyrase poisons that stabilize cleavage complexes of gyrase covalently bound to the DNA, leading to double-strand breaks and cell death. …”
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“…Our calculations reveal that the PdAu SAA exhibits a slightly lower theoretical overpotential, enhanced selectivity for 4‐e(−) ORR, and tolerance to CO‐poisoning compared to Pt(111). While the number of active sites of PdAu SAA is lower than that of Pt(111), the aforementioned desirable properties could bring the overall catalytic performance thereof close to that of Pt/C, indicating that the PdAu SAA could be a viable material for electrocatalytic ORR in PEM fuel‐cells.…”
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“…Currently, electrodes for direct alcohol fuel cells (DAFCs) are mainly based on platinum, which not only provides a poor reaction rate but also readily deactivates because of poisoning by reaction products. Because of these disadvantages, many researchers have focused on developing novel electrode materials with electrocatalytic properties towards the oxidation of simple alcohols, such as methanol, ethanol, ethylene glycol or propanol. …”
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“…Kidneys are particularly susceptible to injury induced by toxins, including poisonous constituents from medicinal plants. The most recognized herb-induced kidney injury is aristolochic acid nephropathy connected with misuse of certain Traditional Chinese herbal medicines. …”
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“…Aflatoxins are poisonous carcinogens produced by fungi, mainly Aspergillus flavus and Aspergillus parasiticus. …”
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“…The diagnosis of ethyl chloride poisoning is primarily clinical and supportive care is the mainstay of treatment, along with subsequent counseling. …”
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“…CONCLUSION: These cases illustrate the spectrum of toxicity, varied presentations, and importance of early recognition and management of chloroquine poisoning. In addition, we can see the importance of sound medical guidance in an era of social confusion compounded by the extremes of public and social media.…”
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