“…Moreover, a new partner molecule of glypican-3, FYCO1 is proposed based on the results from co-precipitation studies.…”
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“…BACKGROUND: Vascular risk factors have been proposed as important targets for the prevention of dementia. …”
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“…OBJECTIVES: Biceps tenodesis has been proposed as an alternative to superior labral anterior posterior (SLAP) repair in older individuals, and there is evidence to suggest it is a reliable operation with low failure rate in these patients. …”
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“…A commonly used indicator for monitoring and assessing progress in coverage of malaria treatment is the proportion of children younger than 5 years with reported fever in the previous 14 days who have received an ACT. We propose an improved indicator that incorporates parasite infection status (as assessed by a rapid diagnostic test [RDT]), which is available in recent household surveys. …”
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“…Further, we did not model or compare the cost-effectiveness of each proposed policy. CONCLUSIONS: Fiscal strategies targeting diet might substantially reduce CVD burdens. …”
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“…BACKGROUND: A new descriptive classification scheme for biomarkers used in Alzheimer's and cognitive aging research, labeled ATN, was recently proposed. One implementation of this ATN construct dichotomizes biomarkers of amyloid, tau, and neurodegeneration/neuronal injury as normal or abnormal resulting in 2 × 2× 2=8 possible biomarker profiles. …”
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“…We could reconfirm the two major advantages of the new inducer-free expression plasmids: (1) Strong repression of the target gene expression in the E. coli cloning strain, and (2) production of the target protein at high levels in B. subtilis in the absence of the inducer. CONCLUSIONS: We propose a general strategy to generate inducer-free expression vector by using IPTG-inducible vectors, and more specifically we developed inducer-free expression plasmids using IPTG-inducible promoters in the absence of the LacI repressor. …”
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“…While the causes of this persistent instability are multifactorial, bony morphologic characteristics have been proposed to play a role. Therefore, the purpose of this study was to evaluate the relationship between the well-described lateral femoral notch (LFN) depth and quantitative measures of rotatory knee stability. …”
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“…Both pre-operative SF-12 MCS and PCS scores are independently predictive of RTP. We propose that the SF-12 is a highly useful post-ACL injury screening tool. …”
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“…Anatomic methods to reconstruct the ACL, including anatomic single-bundle (SB) and double-bundle (DB) reconstruction, have been proposed to improve clinical outcomes after ACL reconstruction. …”
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“…To overcome known shortcomings of the NEI VFQ-25, we calculated the previously proposed visual functioning scale and the socio-emotional scale based on Rasch-transformed person-level data. …”
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“…Primary outcomes were remission and mean standard ethanol consumed in the past 14 days, and the proposed mediating variable was readiness to change at 3 months. …”
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“…Results We found marked differences between the proportions of different types of treatments proposed by patients, carers and clinicians and those currently being evaluated by researchers. …”
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“…Involvement activities take place at the time when researchers are planning studies, and when they are completing application forms to request funding for a proposed research project. After the public involvement activities researchers are asked to write a report for the RDS describing what they did with the public involvement funding. …”
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“…The identification through systematic questioning with structured or semi-structured interviews of youth’s exposure to trauma should be followed by trauma related therapies inside the inpatient setting and/or on an outpatient basis. We also propose that future research should focus on the clinical and social needs of the trauma exposed youth and their societal background and the prevention of manifestations related to psychiatric disorders.…”
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“…Based on a critical review process, we propose a typology with key initiatives to address the knowledge gap in the use of social media for research on prescription drug abuse and addiction. …”
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“…A digital health solution that could potentially compliment the intervention components was proposed. Conclusion The outputs from the 3-day consensus conference, that held patient and public involvement at its core, will help the research team further develop and test the D1 Now intervention for young adults with type 1 diabetes in a pilot and feasibility study and ultimately in a definitive trial. …”
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“…Meanwhile, CBX treatment induced obviously downregulation of p-Cx43(Ser368) and p-PKC(Ser729) protein levels in plasma membrane. CONCLUSIONS: We propose a vicious cycle exists between astrocytic hemichannel and microglial activation after OGD/R injury, which would aggravate neuroinflammatory responses and neuronal damage. …”
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“…Background: The increasing prevalence of diabetes in the United Kingdom and worldwide calls for new approaches to its management, and diets with low glycaemic index have been proposed as a useful means for managing glucose response. …”
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“…BACKGROUND: Latent liability for schizophrenia (schizotypy) is expressed in various combinations of cognitive, psychological, and behavioural characteristics evident in the general population. Historical models propose that distinct classes of individuals expressing different forms of schizotypy may represent manifestations of differential levels of genetic and environmental risk for schizophrenia (or related illness). …”
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