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  1. 358241
    por Khalid, Salema, Smith, Richard, Cole, Zoe
    Publicado 2019
    “…The GiACTA trial showed that treatment with TCZ, while extremely efficacious, did not prevent disease flares in all patients, with 24% of patients in TCZ groups experiencing at least 1 or more disease flares. The trial proposed that the flares might be attributable to Th-1 cells, which are not affected directly by IL-6 receptor blockade, and may play an important role in some patients with GCA. …”
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    20. Tocilizumab: is out of sight really out of mind?
  2. 358242
    por Otieno, Agnes Meave
    Publicado 2019
    “…The study incorporated the stress-buffering model to propose that the beneficial effects of religious social support will modify the association between threat appraisal and well-being for PLHIV in a palliative care setting. …”
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    3529 The main effects of threat appraisal on the well-being of African Americans living with HIV/AIDS in the Washington, D.C. metropolitan area, and the role of religious social support as a buffer
  3. 358243
    “…This is consist with the proposed deleterious role for macrophages in tumor progression. …”
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    2367: Defining critical features of the immune microenvironment in melanoma using multiplex immunohistochemistry and spatial analysis
  4. 358244
    por Mellor, David J.
    Publicado 2019
    “…However, it is noted that such “learning” and “memory” processes are sometimes mistakenly thought to require the fetus to be conscious, a view which does not accord with established understanding of learning processes, nor with compelling contrary evidence from direct studies of fetal brain states. The solution proposed is to describe trans-natal sensory continuity in terms of the neurophysiological mechanisms involved and not as learning and memory outcomes. …”
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    Preparing for Life After Birth: Introducing the Concepts of Intrauterine and Extrauterine Sensory Entrainment in Mammalian Young
  5. 358245
    “…OBJECTIVES: The hypothesis of the proposed intervention is that Granulocyte-macrophage colony-stimulating factor (GM-CSF) has profound effects on antiviral immunity, and can provide the stimulus to restore immune homeostasis in the lung with acute lung injury post COVID-19, and can promote lung repair mechanisms, that lead to a 25% improvement in lung oxygenation parameters. …”
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    Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC): A structured summary of a study protocol for a randomised controlled trial
  6. 358246
    “…INTRODUCTION: Le SARS-CoV-2 est responsable dans sa forme la plus grave d’une pneumonie avec une mortalité importante. Chen et al. ont proposé un score pronostique incluant des données cliniques et biologiques permettant d’identifier les personnes à risque d’évolution péjorative (Chen et al. …”
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    Comparaison des scores de sévérité dans les pneumonies à SARS-CoV-2
  7. 358247
    “…Medical and surgical specialties that manage most cases involving testicular masses may not be aware of the differentials such as sarcoid; clinicians may therefore be exposed to a degree of cognitive bias in these cases. We propose this as an example to improve framing of similar cases for clinicians in the future. …”
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    EP18 Testicular sarcoidosis: a challenging diagnosis
  8. 358248
    por Nizam, Sharmin
    Publicado 2020
    “…Various diagnostic criteria have been proposed using clinical, serological, and/or histological features. …”
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    EP27 Sjögren’s or not: an anxious diagnosis
  9. 358249
    “…Arm III: Kaba Sura Kudineer (The Siddha Medicine which is proposed to be used as a Treatment for COVID 19 based on Siddha Literature) 60 Ml Morning and Night after Food, along with standard Allopathy Treatment for 10 days. …”
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    A double blinded placebo controlled comparative clinical trial to evaluate the effectiveness of Siddha medicines, Kaba Sura Kudineer (KSK) & Nilavembu Kudineer (NVK) along with standard Allopathy treatment in the management of symptomatic COVID 19 patients - a structured summary of a study protocol for a randomized controlled trial
  10. 358250
    “…Despite the potential health risks associated with skin exposure to metal nanoparticles, the mechanisms underlying the toxicity of metal nanoparticles on skin keratinocytes remain unclear. In this study, we proposed that exposure of human epidermal keratinocytes (HaCaT) to metal nanoparticles, such as nickel nanoparticles, dysregulates tight-junction associated proteins by interacting with the HIF-1α/miR-29b/MMPs axis. …”
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    Effects of metal nanoparticles on tight junction-associated proteins via HIF-1α/miR-29b/MMPs pathway in human epidermal keratinocytes
  11. 358251
    “…Methods: The survey was proposed by the ISA Board and approved by the coordinating institution's Ethics Committee. …”
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    Sars-Cov-2 Infection and Systemic Light Chain Amyloidosis: The International Society of Amyloidosis' Survey
  12. 358252
    “…It has been proposed that patients with hematologic malignancy and autoimmune diseases receiving anti-CD20 monoclonal antibody (mAb) therapy are particularly at risk of severe Coronavirus disease (COVID-19) because the profound and long-lasting B-cell depletion induced by anti-CD20 mAb may impair virus clearance and may also contribute to reactivation of latent viruses, especially hepatitis B and JC viruses. …”
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    Impaired Sars-Cov-2 Specific Antibody Responses in Patients Treated with Anti-CD20 Antibodies
  13. 358253
    “…Unfortunately, the case of combined cruciate or collateral ligament with knee extensor structure disruption could not classified in the previous classifications. Therefore, we proposed new classification for MLKI which contains both femorotibial factor and patellofemoral factor. …”
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    Novel classification for multi-ligament knee injury including both tibiofemoral joint factor and patellofemoral joint factor (193)
  14. 358254
    “…Depuis août 2020, un suivi de réévaluation est systématiquement proposé entre M3 et M6 quelle que soit la gravité initiale de l’infection (ambulatoire, hospitalisation sans ou avec oxygénothérapie, réanimation). …”
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    Séquelles physiques et psychiques 3–6 mois après la COVID-19 : premiers résultats de la cohorte prospective ALCOVID
  15. 358255
    “…CONCLUSION: Contrairement aux critères démographiques et à l’activité de la maladie lupique, le mycophénolate mofétil, le méthotrexate et le déficit lymphocytes B naïfs ou en IgG semblent indépendamment associés à une moindre réponse humorale à la vaccination par BNT162b2, devant faire discuter dans ces cas une adaptation du schéma vaccinal, par exemple en proposant une troisième injection.…”
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    Étude des déterminants des réponses immunitaires humorale et cellulaire contre le SARS-CoV-2 et ses variants chez des patients atteints de lupus systémique
  16. 358256
    “…Au cours de la COVID-19, des études suggèrent qu’un état d’épuisement immunitaire en lien avec une anergie et/ou une déplétion des lymphocytes T serait partiellement responsable de la virulence du SARS-CoV-2 [6], [7], [8], [9], [10]. Certains proposent donc l’utilisation des anti-PD1 comme stratégie thérapeutique tandis que d’autres suggèrent qu’au contraire, elle pourrait aggraver l’hyperinflammation [11], [12]. …”
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    Impact des inhibiteurs de checkpoints immunitaires au cours de la COVID-19 chez les patients atteints de mélanome
  17. 358257
    “…In particular, in all non-critical clinical situation, SARS-CoV-2 vaccination should be proposed before the onset of lymphoma/CLL therapy. …”
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    A Third Anti-Sars-Cov2 mRNA Dose Does Not Overcome the Pejorative Impact of Anti-CD20 Therapy and/or Low Immunoglobulin Level in CLL/Lymphoma Patients
  18. 358258
    “…Since severe cases of COVID-19 present a dysregulated immune system with T cell lymphopenia and a hyper-inflammatory state we have proposed that a similar strategy could be proven to be efficient for COVID-19 patients. …”
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    A Phase I/II Dose-Escalation Multi-Center Study to Evaluate the Safety of Infusion of Natural Killer Cells or Memory T Cells As Adoptive Therapy in Coronavirus Pneumonia and/or Lymphopenia: (RELEASE NCT04578210)
  19. 358259
    “…We also question what a plausible cut-off point would be to propose a temporal relationship for an adverse reaction; in the literature, adverse reactions have been postulated to develop beyond 1 month after the provoking agent. …”
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    P28 Multi-system and cavernous sinus inflammatory syndrome presenting with evolving multiple cranial neuropathies following zoledronate infusion
  20. 358260
    “…In view of the cytokine storm which is the significant reason for morbidity and mortality of COVID-19 patients, we proposed to test the usefulness of a multiplex RT-PCR test kit that simultaneously measured inflammatory markers namely, IL-6, TNF– α and IL-10 (IFM) all in one tube. …”
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    Anti-inflammatory response of cardamom extract and prediction of therapeutic window in COVID-19 patients by assessing inflammatory markers using RT-PCR
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