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358321por Waszak, Sebastian M, Northcott, Paul A, Buchhalter, Ivo, Robinson, Giles W, Sutter, Christian, Groebner, Susanne, Grund, Kerstin B, Brugières, Laurence, Jones, David T W, Pajtler, Kristian W, Morrissy, A Sorana, Kool, Marcel, Sturm, Dominik, Chavez, Lukas, Ernst, Aurelie, Brabetz, Sebastian, Hain, Michael, Zichner, Thomas, Segura-Wang, Maia, Weischenfeldt, Joachim, Rausch, Tobias, Mardin, Balca R, Zhou, Xin, Baciu, Cristina, Lawerenz, Christian, Chan, Jennifer A, Varlet, Pascale, Guerrini-Rousseau, Lea, Fults, Daniel W, Grajkowska, Wiesława, Hauser, Peter, Jabado, Nada, Ra, Young-Shin, Zitterbart, Karel, Shringarpure, Suyash S, De La Vega, Francisco M, Bustamante, Carlos D, Ng, Ho-Keung, Perry, Arie, MacDonald, Tobey J, Hernáiz Driever, Pablo, Bendel, Anne E, Bowers, Daniel C, McCowage, Geoffrey, Chintagumpala, Murali M, Cohn, Richard, Hassall, Timothy, Fleischhack, Gudrun, Eggen, Tone, Wesenberg, Finn, Feychting, Maria, Lannering, Birgitta, Schüz, Joachim, Johansen, Christoffer, Andersen, Tina V, Röösli, Martin, Kuehni, Claudia E, Grotzer, Michael, Kjaerheim, Kristina, Monoranu, Camelia M, Archer, Tenley C, Duke, Elizabeth, Pomeroy, Scott L, Shelagh, Redmond, Frank, Stephan, Sumerauer, David, Scheurlen, Wolfram, Ryzhova, Marina V, Milde, Till, Kratz, Christian P, Samuel, David, Zhang, Jinghui, Solomon, David A, Marra, Marco, Eils, Roland, Bartram, Claus R, von Hoff, Katja, Rutkowski, Stefan, Ramaswamy, Vijay, Gilbertson, Richard J, Korshunov, Andrey, Taylor, Michael D, Lichter, Peter, Malkin, David, Gajjar, Amar, Korbel, Jan O, Pfister, Stefan M“…INTERPRETATION: Genetic counselling and testing should be used as a standard-of-care procedure in patients with MB(WNT) and MB(SHH) because these patients have the highest prevalence of damaging germline mutations in known cancer predisposition genes. We propose criteria for routine genetic screening for patients with medulloblastoma based on clinical and molecular tumour characteristics. …”
Publicado 2018
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358322por Chughtai, Talat, Parchani, Ashok, Strandvik, Gustav, Verma, Vishy, Arumugam, Suresh, El-Menyar, Ayman, Rizoli, Sandro, Al-Thani, Hassan“…Similarly, critically injured trauma patients managed in a dedicated trauma intensive care unit (TICU), has been shown to improve outcomes, especially for polytrauma patients with traumatic brain injury (TBI).(3) In fact, the American College of Surgeons (ACS) Committee on Trauma requires verified trauma centers to have a designated ICU, and that a trauma surgeon be its director.(4) Furthermore, studies have shown that for TBI, it is not necessary for this ICU to be a neurocritical care unit, but rather it should be a unit that is dedicated to trauma, that has standardized protocols for TBI management.(5,6) In fact, the outcomes are better in the latter, with lower mortality in multiple-injured patients with TBI, when admitted to a TICU (versus a medical-surgical ICU or neurocritical care unit).(3) These benefits were shown to increase, with increased injury severity. The proposed reason for this is thought to be due to the associated injuries being managed better.(7) The aim of this editorial is to describe the TICU at Hamad General Hospital (HGH), at Hamad Medical Corporation (HMC), including a comparison of its data and outcomes with other similar trauma centers in the world. …”
Publicado 2020
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358323por Landrigan, Philip J., Stegeman, John J., Fleming, Lora E., Allemand, Denis, Anderson, Donald M., Backer, Lorraine C., Brucker-Davis, Françoise, Chevalier, Nicolas, Corra, Lilian, Czerucka, Dorota, Bottein, Marie-Yasmine Dechraoui, Demeneix, Barbara, Depledge, Michael, Deheyn, Dimitri D., Dorman, Charles J., Fénichel, Patrick, Fisher, Samantha, Gaill, Françoise, Galgani, François, Gaze, William H., Giuliano, Laura, Grandjean, Philippe, Hahn, Mark E., Hamdoun, Amro, Hess, Philipp, Judson, Bret, Laborde, Amalia, McGlade, Jacqueline, Mu, Jenna, Mustapha, Adetoun, Neira, Maria, Noble, Rachel T., Pedrotti, Maria Luiza, Reddy, Christopher, Rocklöv, Joacim, Scharler, Ursula M., Shanmugam, Hariharan, Taghian, Gabriella, van de Water, Jeroen A.J.M., Vezzulli, Luigi, Weihe, Pál, Zeka, Ariana, Raps, Hervé, Rampal, Patrick“…GOALS: (1) Broadly examine the known and potential impacts of ocean pollution on human health. (2) Inform policy makers, government leaders, international organizations, civil society, and the global public of these threats. (3) Propose priorities for interventions to control and prevent pollution of the seas and safeguard human health. …”
Publicado 2020
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358324por Garcia, Patricia J., Mundaca, Hansel, Ugarte-Gil, Cesar, Leon, Patricia, Malaga, German, Chaccour, Carlos, Carcamo, Cesar P.“…To assess the safety of ivermectin at the proposed dose. 5. To determine the magnitude of the immune response against SARS-CoV-2. 6. …”
Publicado 2021
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358325“…BACKGROUND: The coronavirus disease 2019 (COVID‐19) pandemic has resulted in substantial mortality. Some specialists proposed chloroquine (CQ) and hydroxychloroquine (HCQ) for treating or preventing the disease. …”
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358326por Hood, Anna M, Hildenbrand, Aimee K, Rebitski, Joanna, Stallworth, Jasmine, Johnson, Yolanda, Gomes, Stacey, Whitacre, Catharine, Mara, Constance A, Shook, Lisa M, Quinn, Charles T., Raphael, Jean L., Yates, Amber M, Badawy, Sherif M., Thompson, Alexis A., Smith-Whitley, Kim, Hartung, Helge, King, Allison A., Creary, Susan E, Bhasin, Neha, Reader, Steven K, Meier, Emily R., Tubman, Venee N., Crosby, Lori E.“…Crosby: Forma Therapeutics: Honoraria; PCORI: Research Funding; HRSA: Research Funding; Global Blood Therapeutics Panel: Honoraria; Children's Hospital of Philadelphia: Honoraria; Professional Resource Exchange: Patents & Royalties: $30-$60 every other year; SCDAA: Honoraria; NHLBI: Other: Payment for review of LRP Proposals, Research Funding. OFFLABEL DISCLOSURE: Hydroxyurea has been FDA approved for the treatment of sickle cell disease for patients ages 2 years and above but NHLBI and ASH Guidelines recommend it be offered to children as young as age 9 months.…”
Publicado 2021
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358327por Berger, M., Daubin, D., Charriot, J., Klouche, K., Le Moing, V., Arnaud, B., Morquin, D., Jaussent, A., Taourel, P., Hayot, M., Nagot, N., Fesler, P., Roubille, C.“…CONCLUSION: De nombreux patients présentent des séquelles à distance d’une COVID sévère nous incitant à un dépistage systématique afin de proposer une prise en charge adaptée.…”
Publicado 2022
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358328Measurement of the associated production of direct photons and jets with the ATLAS experiment at LHCpor Cascella, Michele“…Several Standard Model extensions like the Higgs boson, super symmetry or extra-dimensions have been proposed to answer these questions. Most of these theories, including the Standard Model predict some new phenomena at the TeV mass scale. …”
Publicado 2012
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358329por Tieulent, Raphaël“…Dans le cadre de ces améliorations, un nouveau détecteur en pixels de silicium (Muon Forward Tracker - MFT) a été proposé et accepté par la collaboration ALICE et le comité LHC, permettant la mesure des muons dans l'acceptance du spectromètre actuel. …”
Publicado 2014
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358330por Sharma, Meenakshi“…Modification to the usual mechanisms of particle production (such as color re-connection, color ropes, string shoving) were proposed to explain such behaviour. These mechanism show better agreement with the experimental data. …”
Publicado 2023
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358331por Köstner, S“…Supersymmetric theories, proposing a bosonic superpartner for each fermion and vice versa, will be tested. …”
Publicado 2005
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358332“…It was not shown, however, that this particular localization was specifically related to the introduction of virus in the left sciatic nerve, or that it could be reversed by inoculating the sciatic nerve of the opposite side. The hypothesis proposed by Hurst, however, finds support in the present instance for (a) the superior colliculi never showed lesions after intracerebral, intranasal, or intramuscular inoculations, and (b) necrosis was produced in either the right or the left superior colliculus, depending on whether the virus was injected into the left or right eyes. …”
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358333por Tremblay, Joël, Bertrand, Karine, Blanchette-Martin, Nadine, Rush, Brian, Savard, Annie-Claude, L’espérance, Nadia, Demers-Lessard, Geneviève, Genois, Rosalie“…METHOD: The method used proposes six steps: (1) targeting the population, (2) estimating the proportion of the population affected by substance misuse and (3) the proportion of youths who should receive services, (4) identifying categories of services, (5) estimating the proportions of youths who should have access to each category of services, and (6) applying the model to real use of services by youths to recalibrate it. …”
Publicado 2019
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358334por Bagacean, Cristina, Letestu, Rémi, Al Nawakil, Chadi, Brichler, Ségolène, Lévy, Vincent, Sritharan, Nanthara, Delmer, Alain, Dartigeas, Caroline, Leblond, Véronique, Roos-Weil, Damien, Béné, Marie C, Clavert, Aline, Chaoui, Driss, Genet, Philippe, Guieze, Romain, Laribi, Kamel, Touileb, Yamina, Drenou, Bernard, Willems, Lise, Tomowiak, Cécile, Merabet, Fatiha, Puppink, Christian, Legendre, Hugo, Troussard, Xavier, Malartre, Stéphanie, Cymbalista, Florence, Michallet, Anne-Sophie“…Post-dose 2 seronegative patients were proposed a third dose and to date, 66 have been tested for the antibody response 4-6 weeks post-dose 3. …”
Publicado 2021
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358335por Samson, M., Nicolas, B., Guilhem, A., Greigert, H., Ciudad, M., Cladiere, C., Straub, C., Blot, M., Piroth, L., Rogier, T., Devilliers, H., Manckoundia, P., Ghesquiere, T., Francois, S., Lakomy, D., Audia, S., Bonnotte, B.“…Ces données méritent d’être confirmées chez un plus grand nombre de patients afin de confirmer ce résultat car cette mesure pourrait permettre de mieux cibler la population de patients à qui proposer précocement un traitement par tocilizumab pour diminuer le risque d’évolution vers une forme grave d’infection à SARS-CoV-2.…”
Publicado 2022
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358336por Wang, X.W., Han, P.J., Bai, F.Y., Luo, A., Bensch, K., Meijer, M., B., Kraak, Han, D.Y., Sun, B.D., Crous, P.W., Houbraken, J.“…Among them, six new genera, six new species, 45 new combinations and three new names are proposed. The results demonstrate that the thermophilic species fall into seven genera (Melanocarpus, Mycothermus, Remersonia, Thermocarpiscus gen. nov., Thermochaetoides gen. nov., Thermothelomyces and Thermothielavioides). …”
Publicado 2022
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358337“…Afin d’améliorer le bien-être des soignants en oncologie, plusieurs ateliers leur sont proposés dans plusieurs centres hospitaliers dans le monde. …”
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358338por Hankache, Robert“…This new observable was proposed by theorists claiming to provide benefits over the inclusive jets observable: no physics correlation are lost and the scales choice is more natural. …”
Publicado 2019
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358339por Barbetti, Matteo“…This statistical method has been used to choose the best strategies for data preparation in order to complete successfully the training process, and to assess the quality reached by different learning algorithms proposed in the literature. The built models are able to output good-looking distributions for the high-level particle identification variables of LHCb, allowing to reproduce a large amount of diverse function shapes starting from track kinematics parameters and a measure of the detector occupancy. …”
Publicado 2022
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358340por Jefferson, Tom, Jones, Mark A., Doshi, Peter, Del Mar, Chris B., Hama, Rokuro, Thompson, Matthew, Spencer, Elizabeth A., Onakpoya, Igho, Mahtani, Kamal R., Nunan, David, Howick, Jeremy, Heneghan, Carl J.“…The influenza virus-specific mechanism of action proposed by the producers does not fit the clinical evidence.…”
Publicado 2014
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