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  1. 2341
    “…We propose that inhibition of the terminal pathway may be beneficial in tauopathies.…”
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    Deficiency of terminal complement pathway inhibitor promotes neuronal tau pathology and degeneration in mice
  2. 2342
    “…To study the cellular fate of premature termination products, we used the antibiotic puromycin as a means to experimentally manipulate prematurely terminated polypeptide production in human cells. …”
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    Premature Translational Termination Products Are Rapidly Degraded Substrates for MHC Class I Presentation
  3. 2343
    “…A novel non-culture based 16S rRNA Terminal Restriction Fragment Length Polymorphism (T-RFLP) method using the restriction enzymes Tsp509I and Hpy166II was developed for the characterization of the nasopharyngeal microbiota and validated using recently published 454 pyrosequencing data. 16S rRNA gene T-RFLP for 153 clinical nasopharyngeal samples from infants with acute otitis media (AOM) revealed 5 Tsp509I and 6 Hpy166II terminal fragments (TFs) with a prevalence of >10%. …”
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    16S rRNA Terminal Restriction Fragment Length Polymorphism for the Characterization of the Nasopharyngeal Microbiota
  4. 2344
    “…BACKGROUND: Non-therapeutic trials in which terminally ill cancer patients are asked to undergo procedures such as biopsies or venipunctures for research purposes, have become increasingly important to learn more about how cancer cells work and to realize the full potential of clinical research. …”
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    Recruiting Terminally Ill Patients into Non-Therapeutic Oncology Studies: views of Health Professionals
  5. 2345
    “…Here, we present the crystal structure of the N-terminal domain of the receptor that encompasses the first 201 amino acids at 2.4 Å resolution. …”
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    Functional Insights from the Crystal Structure of the N-Terminal Domain of the Prototypical Toll Receptor
  6. 2346
    “…Our results suggest that in the context of virus infection transcription termination of the BUNV S genome segment mRNA is exclusively directed by the upstream-termination signal. …”
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    The small genome segment of Bunyamwera orthobunyavirus harbours a single transcription-termination signal
  7. 2347
    “…CONCLUSIONS: The ability of Ca(2+) channels to move within the presynaptic active zone suggests that regulating channel mobility may affect release from bipolar cell terminals.…”
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    Lateral mobility of L-type calcium channels in synaptic terminals of retinal bipolar cells
  8. 2348
    “…RESULTS: In the present study, we have shown that the N-terminal fragment of Slit2 (Slit2N) (~120 kDa) inhibits replication of both CXCR4 and CCR5-tropic HIV-1 viruses in T-cell lines and peripheral blood T-cells. …”
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    N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton
  9. 2349
    “…Here we investigated whether these terminal heterocysts are the exclusive sites for dinitrogen fixation in C. raciborskii. …”
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    Dinitrogen Fixation Is Restricted to the Terminal Heterocysts in the Invasive Cyanobacterium Cylindrospermopsis raciborskii CS-505
  10. 2350
    “…Previously, in Saccharomyces cerevisiae, it has been found that the carboxy-terminal two-thirds of Mgm101p has a functional core. …”
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    The N-Terminal Intrinsically Disordered Domain of Mgm101p Is Localized to the Mitochondrial Nucleoid
  11. 2351
    “…CONCLUSION: According to these findings it can be concluded that only the GalNAc terminal sugar showed temporally regulated changes during the early embryonic development of vertebrae in mice. …”
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    Regulatory Changes of N-Acetylgalactosamine Terminal Sugar in Early Mouse Embryonic Paraxial Mesenchyme
  12. 2352
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    The N-terminal Helix Controls the Transition between the Soluble and Amyloid States of an FF Domain
  13. 2353
    “…We found that dozens of the calyx-type presynaptic terminals and axons were selectively labeled with EGFP fluorescence. …”
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    Optogenetic Probing and Manipulation of the Calyx-Type Presynaptic Terminal in the Embryonic Chick Ciliary Ganglion
  14. 2354
    “…To improve applicability, we developed the CTLA-4Ig-CTKC in which the c-terminal lysine had been replaced by cysteine through single amino acid change. …”
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    Functional Characteristics of C-terminal Lysine to Cysteine Mutant Form of CTLA-4Ig
  15. 2355
    “…C-terminal NXT sites were glycosylated more rapidly and efficiently than C-terminal NXS sites. …”
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    Extreme C-terminal sites are posttranslocationally glycosylated by the STT3B isoform of the OST
  16. 2356
    “…Right hemicolectomy was done and the pathological specimen revealed XGI of the terminal ileum. To our knowledge, this is the first case of XGI in terminal ileum presenting as abdominal pain and the appendiceal mass on radiologic findings.…”
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    Xanthogranulomatous Inflammation in Terminal Ileum Presenting as an Appendiceal Mass: Case Report and Review of the Literature
  17. 2357
    “…In addition to suggesting that some posterior features of the terminal system are evolutionarily conserved, our detection of activated ERK in the oocyte, rather than in the embryo, suggests that pea aphids may transduce the terminal signal using a mechanism distinct from the one used in Drosophila. …”
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    The pea aphid uses a version of the terminal system during oviparous, but not viviparous, development
  18. 2358
    “…One of its surface adhesins, Sgo0707, is a large protein composed of a non-repetitive N-terminal region followed by several C-terminal repeat domains and a cell wall sorting motif. …”
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    Structural and Functional Analysis of the N-terminal Domain of the Streptococcus gordonii Adhesin Sgo0707
  19. 2359
    “…Here, we present the cryo-EM structure of a post-termination ribosome containing both apo-RF3 and RF1. …”
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    Cryo-EM visualization of the ribosome in termination complex with apo-RF3 and RF1
  20. 2360
    “…The C(2)H(4) terminated zGNRs (C(2)H(4)-zGNRs) with pure sp(2) coordinated edges can be stabilized at rather mild experimental conditions, and meanwhile reproduce the electronic and magnetic properties of those hydrogen terminated zGNRs. …”
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    Preserving the Edge Magnetism of Zigzag Graphene Nanoribbons by Ethylene Termination: Insight by Clar's Rule
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