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  1. 2561
    “…The C-terminal domain (CTD) of the largest subunit of RNA polymerase II (RNAPII) is required to regulate transcription and to integrate it with other essential cellular processes. …”
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    Repeat-Specific Functions for the C-Terminal Domain of RNA Polymerase II in Budding Yeast
  2. 2562
    “…While numerous binding partners have been identified to NH(2)-terminal Htt, fewer proteins are known to interact with C-terminal domains of Htt. …”
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    The COOH-terminal domain of huntingtin interacts with RhoGEF kalirin and modulates cell survival
  3. 2563
    “…In other cases, DNA synthesis stopped 4–5 nucleotides before the site of the cross-link in single-stranded template or in double-stranded DNA if the polymerases could displace the downstream strand. We suggest that termination of DNA polymerases on a DPC is mostly due to the unrelieved conformational strain experienced by the enzyme when pressing against the cross-linked protein molecule.…”
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    Variable termination sites of DNA polymerases encountering a DNA–protein cross-link
  4. 2564
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    PKA-RII subunit phosphorylation precedes activation by cAMP and regulates activity termination
  5. 2565
    “…More is known about the functions of the N-terminal isoforms of p73 (TAp73 and ΔNp73) and their opposing pro- and anti-apoptotic roles, whereas the functional differences of the distinct C-terminal splice forms of p73 are very far away from been defined. …”
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    p73 Alternative Splicing: Exploring a Biological Role for the C-Terminal Isoforms
  6. 2566
    “…Herein, we report a systematic method for the design of chiral ligands for the enantioselective Markovnikov hydroboration of aliphatic terminal alkenes based on a computational and experimental evaluation sequence. …”
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    Computational design of high-performance ligand for enantioselective Markovnikov hydroboration of aliphatic terminal alkenes
  7. 2567
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    Painful Terminal Neuroma Prevention by Capping PRGD/PDLLA Conduit in Rat Sciatic Nerves
  8. 2568
    “…Background: Serum N-terminal probrain natriuretic peptide (NT-proBNP) level is known to be strongly associated with fluid overload, and serves as a guide for fluid management in patients on hemodialysis (HD). …”
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    Investigation of optimum N-terminal probrain natriuretic peptide level in patients on maintained hemodialysis
  9. 2569
    “…Premature termination codons (PTCs) in the coding regions of mRNA lead to the incorrect termination of translation and generation of non-functional, truncated proteins. …”
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    Advances in therapeutic use of a drug-stimulated translational readthrough of premature termination codons
  10. 2570
    “…Between P15 and P30, both MEC regions showed an increase in PV(+) terminal size and percentage of PV(+) terminals containing mitochondria, which may enable grid cell activity to emerge and stabilize. …”
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    Development of Parvalbumin-Expressing Basket Terminals in Layer II of the Rat Medial Entorhinal Cortex
  11. 2571
    “…With the aid of dibenzo-18-crown-6 and 2.2.2-cryptand, it was possible to isolate a terminal sulfido species, capped by the potassium counter ion, and a “free” terminal sulfido species with a well separated cation/anion pair. …”
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    Uranium(iv) terminal hydrosulfido and sulfido complexes: insights into the nature of the uranium–sulfur bond
  12. 2572
    “…In this article, we review the literature regarding the role of c-Jun N-terminal kinases (JNKs) in cerebral and myocardial ischemia/reperfusion injury. …”
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    c-Jun N-Terminal Kinases (JNKs) in Myocardial and Cerebral Ischemia/Reperfusion Injury
  13. 2573
    “…The three STY kinases were shown to phosphorylate the N-terminal sequences of some proteins we tested but exhibited different specificities. …”
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    Multiple Kinases Can Phosphorylate the N-Terminal Sequences of Mitochondrial Proteins in Arabidopsis thaliana
  14. 2574
    “…Here, we show that glutamate release from mossy fiber terminals triggers action potential firing of the target CA3 pyramidal neurons independently of the average granule cell burst frequency, a phenomenon we term action potential counting. …”
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    Action potential counting at giant mossy fiber terminals gates information transfer in the hippocampus
  15. 2575
    “…At parallel fibre terminals in the cerebellar cortex, glutamate released outside of the active zone can activate AMPA receptors on juxtaposed Bergmann glial cell processes. …”
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    Distribution of vesicle pools in cerebellar parallel fibre terminals after depression of ectopic transmission
  16. 2576
    “…Correction for ‘Iminoboronates are efficient intermediates for selective, rapid and reversible N-terminal cysteine functionalisation’ by Hélio Faustino et al., Chem. …”
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    Correction: Iminoboronates are efficient intermediates for selective, rapid and reversible N-terminal cysteine functionalisation
  17. 2577
    por Ahmed, Nisar, Khatoon, Saira
    Publicado 2018
    “…During electrolysis, a nitrogen radical was formed at the urea substrate that cyclised with the alkene and generated a terminal carbon radical which further formed a bond with the 2,2,6,6‐tetramethylpiperidine‐N‐oxyl radical (TEMPO). …”
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    Facile Electrochemical Intramolecular Amination of Urea‐Tethered Terminal Alkenes for the Synthesis of Cyclic Ureas
  18. 2578
    “…Despite previous biochemical studies suggesting the catalytic importance of the C-terminal tyrosine residue found in several bacterial DERAs, the structural and functional basis of its participation in catalysis remains elusive because the electron density for the last eight to nine residues (i.e., the C-terminal tail) is absent in all available crystal structures. …”
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    Conformational Sampling of the Intrinsically Disordered C-Terminal Tail of DERA Is Important for Enzyme Catalysis
  19. 2579
    “…Methods for site-selective chemistry on proteins are in high demand for the synthesis of chemically modified biopharmaceuticals, as well as for applications in chemical biology, biosensors and more. Inadvertent N-terminal gluconoylation has been reported during expression of proteins with an N-terminal His tag. …”
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    Selective N-terminal acylation of peptides and proteins with a Gly-His tag sequence
  20. 2580
    “…The extended and flexible C-terminal residues are confirmed by (15)N relaxation analysis and molecular dynamics simulation. …”
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    NMR structure of the C-terminal domain of TonB protein from Pseudomonas aeruginosa
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