“…Therapy termination rates were highest in younger or older patients with ≥1 comorbidity. …”
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“…Arabidopsis cyclophilin38 (CYP38) is a thylakoid lumen protein critial for PSII assembly and maintenance, and its C-terminal region serves as the target binding domain. …”
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“…Here we present the high-resolution structure of the eukaryotic Box C/D methyltransferase Nop1 from Saccharomyces cerevisiae bound to the amino-terminal domain of Nop56. We discuss similarities and differences between the interaction modes of the two proteins in archaea and eukaryotes and demonstrate that eukaryotic Nop56 recruits the methyltransferase to the Box C/D RNP through a protein–protein interface that differs substantially from the archaeal orthologs. …”
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“…Besides a well‐established activity control by regulatory proteins, an inhibitory function for phosphorylation (p) of a Thr residue in the C‐terminal intrinsically disordered tail of PP1 has been demonstrated. …”
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“…Wheat crop experiences high temperature stress during flowering and grain-filling stages, which is termed as “terminal heat stress”. Characterizing genotypes for adaptive traits could increase their selection for better performance under terminal heat stress. …”
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“…Our results provide the first evidence of FP in this species, and provide novel evidence that rejects gametic duplication and supports terminal fusion as a mechanism underlying parthenogenesis in snakes. …”
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“…In this paper, a polyurethane prepolymer was treated with an isocyanate, and then the isocyanate-terminated polyurethane prepolymer and poplar powder were used to prepare modified lignin-based phenolic foams (PUPFs), which improved the abrasion resistance and decreased the pulverization of the foam. …”
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“…Here, we describe a case of full-mouth reconstruction with implant-supported prosthesis in a young individual who lost all her teeth due to extensive caries. The journey from terminal dentition to functional esthetic rehabilitation was uneventful.…”
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“…Premature termination codon (PTC) readthrough is considered a potential treatment for genetic diseases caused by nonsense mutations. …”
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“…We describe the phenotype associated with a novel variant in the terminal codon of the RPGR(ORF15) c.3457T>A (Ter1153Lysext*38), which results in a C-terminal extension. …”
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“…The protocol can be applied to a wide variety of terminal alkynes including both alkyl- and arylalkynes.…”
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“…Human Nbs1, a component of the MRN complex involved in DNA double strand break repair, contains a concatenated N-terminal FHA-BRCT1/2 sequence that supports interaction with multiple phosphopeptide binding partners. …”
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“…While previous studies in C. elegans have confirmed the localization of either transgenic HIM-4::GFP or endogenous C-terminally tagged HIM-4::mNeonGreen, only green or green/yellow fluorescent protein-tagged HIM-4 are available to the C. elegans community. …”
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“…Here we characterize the structural basis for substrate recognition and discrimination by the N-terminal domain (NTD) of LonA. The results reveal that the six NTDs are attached to the hexameric LonA chamber by flexible linkers such that the formers tumble independently of the latter. …”
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“…Receptor activation involves glycine- and glutamate-stabilized closure of the GluN1 and GluN2 subunit ligand binding domains that is allosterically regulated by the amino-terminal domain (ATD). Using single molecule fluorescence resonance energy transfer (smFRET) to monitor subunit rearrangements in real-time, we observe a stable ATD inter-dimer distance in the Apo state and test the effects of agonists and antagonists. …”
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“…In SMA mouse models, motor nerve terminals display neurotransmitter release reduction, endocytosis decrease and mitochondria alterations. …”
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“…The present study was conducted to explore the informational and educational needs of women who have experienced pregnancy termination because of fetal anomalies. MATERIALS AND METHODS: The present study was a qualitative content analysis. …”
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