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  1. 3001
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    Ocean warming drives rapid dynamic activation of marine-terminating glacier on the west Antarctic Peninsula
  2. 3002
    por Sato, Hajime, Frantz, Janet E
    Publicado 2005
    “…This delayed policy termination caused a deprivation of civil liberties of the involuntarily confined patients, the fostering of social stigmas attached to the disease, and an inefficient use of health resources. …”
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    Termination of the leprosy isolation policy in the US and Japan : Science, policy changes, and the garbage can model
  3. 3003
    “…Because the observed effect of the encoded N-terminal extension is not specific to Tdk production and can be overcome with induction of gene expression, these results may have particular relevance to researchers attempting to limit production of toxic proteins under non-inducing conditions.…”
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    An encoded N-terminal extension results in low levels of heterologous protein production in Escherichia coli
  4. 3004
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    Characterization of the metal ion binding site in the anti-terminator protein, HutP, of Bacillus subtilis
  5. 3005
    “…To examine the role of the extensions on IF3(mt), deletion constructs were prepared in which the N-terminal extension, the C-terminal extension or both extensions were deleted. …”
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    Role of the N- and C-terminal extensions on the activity of mammalian mitochondrial translational initiation factor 3
  6. 3006
    por Winegar, Bruce D, MacIver, M Bruce
    Publicado 2006
    “…BACKGROUND: Anesthetic-induced CNS depression is thought to involve reduction of glutamate release from nerve terminals. Recent studies suggest that isoflurane reduces glutamate release by block of Na channels. …”
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    Isoflurane depresses hippocampal CA1 glutamate nerve terminals without inhibiting fiber volleys
  7. 3007
    “…The minimal transcriptional AD was mapped to approximately 91 C-terminal amino acids and consists of acidic, serine/proline-rich and phenylalanine-rich subdomains. …”
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    Downstream signaling mechanism of the C-terminal activation domain of transcriptional coactivator CoCoA
  8. 3008
    “…We screened a cDNA library from human microvascular endothelial cells with serum IgG from two patients with Behçet's disease and isolated a reactive clone specific to the carboxy-terminal subunit of Sip1 (Sip1 C-ter). Using ELISA, we measured IgG, IgM and IgA specific to Sip1 C-ter in patients with various autoimmune diseases characterized by the presence of serum anti-endothelial cell antibodies, such as Behçet's disease, systemic lupus erythematosus, systemic sclerosis and various forms of primary vasculitis, as well as in patients with diseases that share clinical features with Behçet's disease, such as inflammatory bowel disease and uveitis. …”
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    Identification and characterization of the carboxy-terminal region of Sip-1, a novel autoantigen in Behçet's disease
  9. 3009
    “…One of these antibodies, mAb33, which is specific for the C-terminal domain, was found to inhibit HIV-1 IN processing activity in vitro; a corresponding Fv fragment was able to inhibit HIV-1 integration in vivo. …”
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    Mode of inhibition of HIV-1 Integrase by a C-terminal domain-specific monoclonal antibody*
  10. 3010
    “…METHODS: Terminal cancer patients hospitalized during the recruiting period voluntarily participated in in-depth interviews. …”
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    Psychological process from hospitalization to death among uninformed terminal liver cancer patients in Japan
  11. 3011
    “…As all participants underwent viral relapse in Step II, the study was terminated after 28 participants completed Step II. …”
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    Immunotherapy with Canarypox Vaccine and Interleukin-2 for HIV-1 Infection: Termination of a Randomized Trial
  12. 3012
    “…RESULTS: A de novo deletion [46,XX del(4)(q32)] was identified cytogenetically and confirmed as a terminal loss via subtelomere FISH. Hand/foot malformation characteristic of deletion at this segment was present. …”
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    Further phenotypic delineation of subtelomeric (terminal) 4q deletion with emphasis on intracranial and reproductive anatomy
  13. 3013
    “…BACKGROUND: In many prokaryotes, transcription of DNA to RNA is terminated by a thymine-rich stretch of DNA following a hairpin loop. …”
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    Rapid, accurate, computational discovery of Rho-independent transcription terminators illuminates their relationship to DNA uptake
  14. 3014
    “…Optimized methods for extraction and enzyme assay in crude tissue preparations were used to determine the amounts of terminal deoxnucleotidyl transferase (TdT) in malignant lymphomas. …”
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    Terminal deoxynucleotidyl transferase in human lymphomas: possible existence of forms with high and low molecular weights.
  15. 3015
    “…Genetic interactions between DFsn and highwire mutants indicate that DFsn and Highwire collaborate to restrain synaptic terminal growth. Finally, DFsn regulates the levels of the Wallenda/DLK kinase, and wallenda is necessary for DFsn-dependent synaptic terminal overgrowth. …”
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    DFsn collaborates with Highwire to down-regulate the Wallenda/DLK kinase and restrain synaptic terminal growth
  16. 3016
    “…We now show that the required function of the NH(2)-terminal regulatory domain (NRD) of the yeast plasma membrane syntaxin, Sso1p, can be circumvented when t-SNARE complex formation is made intramolecular. …”
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    An intramolecular t-SNARE complex functions in vivo without the syntaxin NH(2)-terminal regulatory domain
  17. 3017
    “…We show that Spastin assembles into a hexamer and that loops within the central pore recognize C-terminal amino acids of tubulin. Key pore loop amino acids are required for severing, including one altered by a disease-associated mutation. …”
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    Recognition of C-terminal amino acids in tubulin by pore loops in Spastin is important for microtubule severing
  18. 3018
    “…The mammalian mitochondrial transcription termination factor mTERF binds with high affinity to a site within the tRNA(Leu(UUR)) gene and regulates the amount of read through transcription from the ribosomal DNA into the remaining genes of the major coding strand of mitochondrial DNA (mtDNA). …”
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    The mitochondrial transcription termination factor mTERF modulates replication pausing in human mitochondrial DNA
  19. 3019
    Publicado 1979
    “…The data further suggest that the initiation and termination of the response are mediated by cellular component(s) beyond cAMP-occupied receptors.…”
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    Cyclic 3',5' AMP relay in Dictyostelium discoideum. II. Requirements for the initiation and termination of the response
  20. 3020
    Publicado 1982
    “…We propose that the transfer of 125I label from T-tubules to terminal cisternae during reformation and breakage of the triad junction is a property of the protein which spans the gap between T-tubules and terminal cisternae.…”
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    Identification of a constituent of the junctional feet linking terminal cisternae to transverse tubules in skeletal muscle
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