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  1. 3141
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    Amino-Terminal Microdeletion within the CNTNAP2 Gene Associated with Variable Expressivity of Speech Delay
  2. 3142
    “…Phosphorylation of the arginine-rich carboxy-terminal domain (CTD) of the HBV capsid protein (Cp183) is essential for pgRNA encapsidation and reverse transcription. …”
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    Structural Organization of Pregenomic RNA and the Carboxy-Terminal Domain of the Capsid Protein of Hepatitis B Virus
  3. 3143
    “…We demonstrate that the N-terminal fused T4L is sufficiently rigid relative to the receptor to facilitate crystallogenesis without thermostabilizing mutations or the use of a stabilizing antibody, G protein, or protein fused to the 3rd intracellular loop. …”
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    N-Terminal T4 Lysozyme Fusion Facilitates Crystallization of a G Protein Coupled Receptor
  4. 3144
    “…A putative mechanism allowing prostate cancer (PCa) cells to grow under low levels of androgens, is the expression of constitutively active, C-terminally truncated AR lacking the AR-ligand binding domain (LBD). …”
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    Effects of Sorafenib on C-Terminally Truncated Androgen Receptor Variants in Human Prostate Cancer Cells
  5. 3145
    “…To better understand V. cholerae Hfq structure and mechanism, we characterized the protein, alongside Escherichia coli Hfq for comparison, using biochemical and biophysical techniques. The N-terminal domain (NTD) of the two proteins is highly conserved, but the C-terminal regions (CTRs) vary in both sequence and length. …”
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    Characterization of Vibrio cholerae Hfq Provides Novel Insights into the Role of the Hfq C-Terminal Region
  6. 3146
    “…We show that OX40 engagement, in the context of chemotherapy-induced lymphopenia, induces a novel CD4(+) T cell population characterized by the expression of the master regulator eomesodermin that leads to both terminal differentiation and central memory phenotype, with concomitant secretion of Th1 and Th2 cytokines. …”
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    Induction of tumoricidal function in CD4(+) T cells is associated with concomitant memory and terminally differentiated phenotype
  7. 3147
    “…Bacteriophages φ29 and Nf from Bacillus subtilis start replication of their linear genomes at both ends using a protein-primed mechanism by means of which the DNA polymerase initiates replication by adding dAMP to the terminal protein, this insertion being directed by the second and third 3′ terminal thymine of the template strand, respectively. …”
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    The Essential Role of the 3′ Terminal Template Base in the First Steps of Protein-Primed DNA Replication
  8. 3148
    “…APLP2 and APP undergo regulated intramembrane proteolysis to produce C-terminal fragments. In this study, we found comprehensive expression of APLP2 C-terminal fragments in a panel of pancreatic cancer cell lines; however, APP C-terminal fragments were notably limited to the BxPC3 cell line. …”
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    Relevance of amyloid precursor-like protein 2 C-terminal fragments in pancreatic cancer cells
  9. 3149
    “…A series of small synthetic arginine and tryptophan containing peptides was prepared and analyzed for their antibacterial activity. The effect of N-terminal substitution with metallocenoyl groups such as ferrocene (FcCO) and ruthenocene (RcCO) was investigated. …”
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    Modulating the activity of short arginine-tryptophan containing antibacterial peptides with N-terminal metallocenoyl groups
  10. 3150
    “…Terminal epoxides undergo lithium 2,2,6,6-tetramethylpiperidide-induced α-lithiation and subsequent interception with Ph(3)P to provide a new and direct entry to β-lithiooxyphosphonium ylides. …”
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    Alkenes from β-lithiooxyphosphonium ylides generated by trapping α-lithiated terminal epoxides with triphenylphosphine
  11. 3151
    “…A subset of VGLUT1-positive terminals also expressed VGLUT2, which decreased at these terminals. …”
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    Developmental Up-Regulation of Vesicular Glutamate Transporter-1 Promotes Neocortical Presynaptic Terminal Development
  12. 3152
    “…It is catalyzed by enzymes called N-terminal acetyltransferases (NATs). In eukaryotes, several NATs, composed of at least one catalytic domain, target different substrates based on their N-terminal sequences. …”
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    Specificity and Versatility of Substrate Binding Sites in Four Catalytic Domains of Human N-Terminal Acetyltransferases
  13. 3153
    “…CONCLUSIONS: Amine-terminated polyacrylonitrile were used as a novel polymeric carrier for benzaldehyde derivatives as antimicrobial agents. …”
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    Biocidal polymers: synthesis and antimicrobial properties of benzaldehyde derivatives immobilized onto amine-terminated polyacrylonitrile
  14. 3154
    por Rhee, K-D, Yu, J, Zhao, C Y, Fan, G, Yang, X-J
    Publicado 2012
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    Dnmt1-dependent DNA methylation is essential for photoreceptor terminal differentiation and retinal neuron survival
  15. 3155
    “…While much research has been focused on AIDS vaccines that target the surface viral envelope (Env) protein, including gp120 and the gp41 ectodomain, the C-terminal tail (CTT) of gp41 has received relatively little attention. …”
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    C-terminal tail of human immunodeficiency virus gp41: functionally rich and structurally enigmatic
  16. 3156
    por Kushwaha, Ambuj K., Grove, Anne
    Publicado 2013
    “…A unique feature of Mycobacterium smegmatis Ku is its basic C-terminal tail that contains several lysine-rich low-complexity PAKKA repeats that are absent from homologues encoded by obligate parasitic mycobacteria. …”
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    C-terminal low-complexity sequence repeats of Mycobacterium smegmatis Ku modulate DNA binding
  17. 3157
    “…RNA-binding assays using purified proteins revealed that Gemin5–IRES interaction depends on the C-terminal region of the protein. Consistent with this novel finding, the C-terminal region of Gemin5, but not the N-terminal region, impaired translation. …”
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    Gemin5 promotes IRES interaction and translation control through its C-terminal region
  18. 3158
    “…RNA Polymerase II (Pol II) termination is dependent on RNA processing signals as well as specific terminator elements located downstream of the poly(A) site. …”
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    AT-rich sequence elements promote nascent transcript cleavage leading to RNA polymerase II termination
  19. 3159
    “…The efficiency and small memory requirements of our approach stem from the use of suffix trees to identify all DNA segments surrounded by user-specified terminal inverse repeats (TIR) and target site duplications (TSD) which together constitute a mask. …”
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    TIRfinder: A Web Tool for Mining Class II Transposons Carrying Terminal Inverted Repeats
  20. 3160
    “…Upf1 activation occurs when Upf2 binds its N-terminal domain, switching the enzyme to the active form. …”
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    Tight intramolecular regulation of the human Upf1 helicase by its N- and C-terminal domains
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