Mostrando 3,241 - 3,260 Resultados de 89,521 Para Buscar '"The Terminal"', tiempo de consulta: 0.56s Limitar resultados
  1. 3241
  2. 3242
    “…RESULTS: In this work, a trivalent single-chain fragment variable (scFv)-based N-terminal trimerbody, specific for the human carcinoembryonic antigen (CEA), was expressed in human embryonic kidney 293 cells and in Pichia pastoris. …”
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  3. 3243
  4. 3244
    “…This impaired functionality is associated with conformational changes in the N-terminal region. Our results strongly point to the role of the Asp-72 site in stabilizing the N-terminal segment of human tropoelastin and the importance of this region in facilitating elastic fiber assembly.…”
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  5. 3245
  6. 3246
  7. 3247
    “…OBJECTIVE: To assess the prognostic value of 12-months N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP) levels on adverse cardiovascular events in patients with stable coronary heart disease. …”
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  8. 3248
    “…We tested N- (α-syn residues 43–140) and C-terminally (1–95) truncated α-syn, and found that similar to full-length protein both truncated species formed soluble DA:α-syn oligomers, albeit 1–95 had a different profile. …”
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  9. 3249
  10. 3250
  11. 3251
  12. 3252
    “…Here, we describe the solution structure of the C-terminal domains of the archaeal MCMs of Sulfolobus solfataricus (Sso) and Methanothermobacter thermautotrophicus (Mth). …”
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  13. 3253
    “…In the present work we have studied the involvement of the TP N-terminal domain residues responsible for DNA binding in the different stages of viral DNA replication by assaying the in vitro activity of purified TP N-terminal mutant proteins. …”
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  14. 3254
    por Park, Jieun, Kang, Myungjin, Kim, Minkyu
    Publicado 2015
    “…Using in vitro transcription termination assays, we have found that RNAPII is prone to more effective termination by Rat1/Rai1 when its catalytic site is disrupted due to NTP misincorporation, implying that paused RNAPII, which is often found in vivo near termination sites, could adopt a similar configuration to Rat1/Rai1 and trigger termination. …”
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  15. 3255
    “…Heart amyloid fibrils were found to be mainly constituted by the 93-residue N-terminal fragment of ApoA-I, named [1–93]ApoA-I. In this paper, rat cardiomyoblasts were used as target cells to analyse binding, internalization and intracellular fate of the fibrillogenic polypeptide in comparison to full-length ApoA-I. …”
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  16. 3256
    “…METHODS: Retrospective medical data of 244 terminally ill cancer patients including 82 sedated patients were collected. …”
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  17. 3257
    “…The chaperoning function of Hsp90 is intimately coupled to the ATPase activity presented by its N-terminal domain. However, the molecular mechanism for the ATP-dependent working cycle of Hsp90 is still not fully understood. …”
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  18. 3258
    “…The exact function of the protein within the process remains unknown. The N-terminal region of the protein includes a well conserved region shown to be involved in PeBoW complex formation whereas the carboxy-terminal half was predicted to contain seven WD40 repeats. …”
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  19. 3259
    “…Polycystin-2 (PC2) belongs to the transient receptor potential (TRP) family and forms a Ca(2+)-regulated channel. The C-terminal cytoplasmic tail of human PC2 (HPC2 Cterm) is important for PC2 channel assembly and regulation. …”
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  20. 3260
    “…Here we tested the hypothesis that the strength of CB(1)-mediated modulation of GABA release is related to the CB(1) content of axon terminals. Basket cell boutons have on average 78% higher CB(1) content than those of dendritic-layer-innervating (DLI) cells, a consequence of larger bouton surface and higher CB(1) density. …”
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