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3341por Hooker, Stephanie A., Ross, Kaile M., Ranby, Krista W., Masters, Kevin S., Peters, John C., Hill, James O.“…Even when individuals attempt to become more active by joining a fitness center, estimates suggest that nearly half terminate their membership within the first 6 months. …”
Publicado 2016
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3342por Yajima, Ryo, Matsumoto, Kazuaki, Ise, Yuya, Suzuki, Norihito, Yokoyama, Yuta, Kizu, Junko, Katayama, Shiro“…Therefore, the aim of the present study was to clarify the problems of pain control after pregabalin discontinuation in terminally ill cancer patients. METHODS: Our subjects comprised cancer patients who died during their hospital stay and were referred between April 2013 and October 2015 to the palliative care team of the 899-bed Cancer Hospital at the Nippon Medical School Hospital in Japan. …”
Publicado 2016
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3343por Hartlerode, Andrea J., Willis, Nicholas A., Rajendran, Anbazhagan, Manis, John P., Scully, Ralph“…If termination of gene conversion occurs in regions lacking homology with the second end of the break, the normal mechanism of HR termination by annealing (i.e., homologous pairing) is not available and termination must occur by as yet poorly defined non-canonical mechanisms. …”
Publicado 2016
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3344por Huber, Nina, Bieniossek, Christoph, Wagner, Konstanze Marion, Elsässer, Hans-Peter, Suter, Ueli, Berger, Imre, Niemann, Axel“…Using recombinant protein, we demonstrate for the first time theta-class-like GST activity for GDAP1, and it’s activity being regulated by the C-terminal hydrophobic domain 1 (HD1) of GDAP1 in an autoinhibitory manner. …”
Publicado 2016
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3345Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residuespor Coey, Christopher T., Malik, Shuja S., Pidugu, Lakshmi S., Varney, Kristen M., Pozharski, Edwin, Drohat, Alexander C.“…Crystal structures and NMR experiments demonstrate that most of these N-terminal residues are disordered, for substrate- or product-bound TDG(82-308). …”
Publicado 2016
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3346“…In this tree, evaluating the accuracy of predicted classes (terminal nodes) is clinically of special importance. …”
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3347por Si, Yunlong, Wang, Yue, Gao, Jin, Song, Chenyang, Feng, Shiqiong, Zhou, Yifa, Tai, Guihua, Su, Jiyong“…Observation of two Gal-8 N-terminal CRD structures implies that the N-terminal tail and the linker may influence each other’s conformation. …”
Publicado 2016
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3348“…We report a case of RNRVAS-induced atrial fibrillation (AF) terminated with implantable cardioverter defibrillator (ICD) shock in a 74-year old female with no prior history of AF.…”
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3349por Nijman, Tobias A. J., Voogdt, Kevin G. J. A., Teunissen, Pim W., van der Voorn, Patrick J. (JP), de Groot, Christianne J. M., Bakker, Petra C. A. M.“…The aim of this study was to determine the incidence of fever in terminations of pregnancy (TOP) using misoprostol and to evaluate fever as indication of intra uterine infection. …”
Publicado 2017
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3350“…Recent evidence suggests these channels also exist pre-synaptically in a subset of synaptic terminals within the mature entorhinal cortex (EC). …”
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3351por Lin, Jian-Ping, Shi, Zhan-Jun, Shen, Ning-Jiang, Wang, Jian, Li, Zao-Min, Xiao, Jun“…The serum concentrations of osteocalcin (OC) and bone-specific alkaline phosphatase (BSAP) served as markers of bone formation, and those of C-terminal telopeptide of type I collagen (CTX), N-terminal telopeptide of type I collagen (NTX) and tartrate-resistant acid phosphatase 5b (TRACP 5b) served as markers of bone resorption. …”
Publicado 2016
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3352“…Among IQ(V) (preIQ(3)-IQ domain), PCRD and DCRD (proximal or distal C-terminal regulatory domain), spatial closeness of any two modules, e.g., by constitutive fusion, facilitates the trio to form the complex, compete against calmodulin, and alter the gating. …”
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3353por Vlakh, E. G., Grachova, E. V., Zhukovsky, D. D., Hubina, A. V., Mikhailova, A. S., Shakirova, J. R., Sharoyko, V. V., Tunik, S. P., Tennikova, T. B.“…In this communication we report on the synthesis of amphiphilic polypeptides bearing C-terminal phosphorescent label together with preparation of nanoparticles using the polypeptides obtained. …”
Publicado 2017
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3354“…BACKGROUND: Pregnancy termination for fetal abnormality (TFA) may have profound psychological consequences for those involved. …”
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3355
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3356por Poksay, Karen S., Sheffler, Douglas J., Spilman, Patricia, Campagna, Jesus, Jagodzinska, Barbara, Descamps, Olivier, Gorostiza, Olivia, Matalis, Alex, Mullenix, Michael, Bredesen, Dale E., Cosford, Nicholas D. P., John, Varghese“…One process that could contribute to this loss is the intracellular caspase cleavage of the amyloid precursor protein (APP) resulting in release of the toxic C-terminal 31-amino acid peptide APP-C31 along with the production of APPΔC31, full-length APP minus the C-terminal 31 amino acids. …”
Publicado 2017
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3357
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3358
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3359“…Large amplitude variations in atmospheric CO(2) were associated with glacial terminations of the Late Pleistocene. Here we provide multiple lines of evidence suggesting that the ∼20 p.p.m.v. overshoot in CO(2) at the end of Termination 2 (T2) ∼129 ka was associated with an abrupt (≤400 year) deepening of Atlantic Meridional Overturning Circulation (AMOC). …”
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3360The C-terminal domain of connexin43 modulates cartilage structure via chondrocyte phenotypic changespor Gago-Fuentes, Raquel, Bechberger, John F., Varela-Eirin, Marta, Varela-Vazquez, Adrian, Acea, Benigno, Fonseca, Eduardo, Naus, Christian C., Mayan, Maria D.“…Reduced Cx43 connectivity decreases chondrocyte differentiation and defective Cx43 causes skeletal defects. The carboxy terminal domain (CTD) of Cx43 is located in the cytoplasmic side and is key for protein functions. …”
Publicado 2016
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