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  1. 3481
    por Burroughs, A. Maxwell, Aravind, L
    Publicado 2019
    “…Thus, we reconstruct the possible state of translation termination in the Last Universal Common Ancestor with possible tRNA-like terminators. …”
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    The Origin and Evolution of Release Factors: Implications for Translation Termination, Ribosome Rescue, and Quality Control Pathways
  2. 3482
    “…In our study, carboxyl-terminated PAMAM dendrimer G3.5 was grafted with poly (ethylene glycol) methyl ether (mPEG) to be employed as a nano-based drug delivery system with great cytocompatibility for the delivery of carboplatin (CPT), a widely prescribed anticancer drug with strong side effects so that the drug will be effectively entrapped and not exhibit uncontrolled outflow from the open structure of unmodified PAMAM G3.5. …”
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    Modified Carboxyl-Terminated PAMAM Dendrimers as Great Cytocompatible Nano-Based Drug Delivery System
  3. 3483
    “…Transmissible gastroenteritis virus (TGEV) is the etiologic agent of transmissible gastroenteritis in pigs, and the N-terminal domain of TGEV spike protein is generally recognized as both the virulence determinant and enteric tropism determinant. …”
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    The N-Terminal Domain of Spike Protein Is Not the Enteric Tropism Determinant for Transmissible Gastroenteritis Virus in Piglets
  4. 3484
    “…The interaction of the A3G N-terminal domain (NTD) with RNA is essential for A3G incorporation in the HIV-1 virion. …”
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    Structural Determinants of the APOBEC3G N-Terminal Domain for HIV-1 RNA Association
  5. 3485
    “…To reduce the muscular exertion of an operator wiring terminal blocks on a vertical plane, a chair with a unique back that can be used as a back support or arm support is proposed in this study. …”
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    Evaluation of a proposed chair with an arm support for wiring terminal blocks on a vertical plane
  6. 3486
    “…Our findings demonstrate that the dyskerin-hTR interaction mediated by PUA and N-terminal residues of dyskerin is crucial to prevent unchecked hTR degradation.…”
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    N-terminal residues of human dyskerin are required for interactions with telomerase RNA that prevent RNA degradation
  7. 3487
    por Valencia, Joseph D., Girgis, Hani Z.
    Publicado 2019
    “…BACKGROUND: Long terminal repeat retrotransposons are the most abundant transposons in plants. …”
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    LtrDetector: A tool-suite for detecting long terminal repeat retrotransposons de-novo
  8. 3488
    “…The results indicate that (a) the degree of conformational freedom of the C‐terminal domain of Smyd2 is restricted by the presence of the p53 peptide substrate, (b) the Smyd2 C‐terminal domain shows distinct dynamic properties when interacting with unmethylated and methylated p53 peptides, and (c) Lys372 methylation confines the p53 peptide conformation, with detectable influence on Lys370 accessibility to the cofactor. …”
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    Smyd2 conformational changes in response to p53 binding: role of the C‐terminal domain
  9. 3489
    “…Currently, reported affinity pairings still lack in diversity, and thus terminal protection relying on steric hindrance is restricted in designing nucleic acid-based analytical systems. …”
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    Substrate specificity-enabled terminal protection for direct quantification of circulating MicroRNA in patient serums
  10. 3490
    “…BACKGROUND: The implementation of molecular karyotyping has resulted in an improved diagnostic yield in the genetic diagnostics of congenital anomalies, detected prenatally or after the termination of pregnancy. However, the systematic epidemiologic ascertainment of copy number variations in the etiology of congenital anomalies has not yet been sufficiently explored. …”
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    The frequency of CNVs in a cohort population of consecutive fetuses with congenital anomalies after the termination of pregnancy
  11. 3491
    “…INTERVENTIONS AND OUTCOMES: Five terminally ill children affected by solid tumors received propofol-based palliative sedation. …”
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    Propofol-based palliative sedation in terminally ill children with solid tumors: A case series
  12. 3492
    “…MATERIAL AND METHODS: This was a prospective study including 34 fetuses from pregnancies terminated in the second trimester due to fetal anomalies. …”
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    Postmortem magnetic resonance imaging vs autopsy of second trimester fetuses terminated due to anomalies
  13. 3493
    “…Here, we characterized how the N-terminal domain (NTD) of the Saccharomyces cerevisiae Pif1 helicase affects its functions both in vivo and in vitro. …”
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    The Biochemical Activities of the Saccharomyces cerevisiae Pif1 Helicase Are Regulated by Its N-Terminal Domain
  14. 3494
    “…[Image: see text] The intensity ratio between the first (373 nm) and the third (383 nm) vibronic peaks [I(1)/I(3), as the pyrene (Py) scale] of fluorescent Py was used to monitor the critical concentration, drug-loading, and -releasing behaviors of a Py-terminated, amphiphilic polypeptide PPM and its hydrogen-bonded interpolymer complex (HIPC) with poly(acrylic acid) (PAA). …”
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    Pyrene-Terminated, Amphiphilic Polypeptide and Its Hydrogen-Bonded Interpolymer Complex as Delivery Systems of Doxorubicin
  15. 3495
    “…Dyes containing electron-releasing terminal groups such as triphenylamine and carbazole exhibited positive emission solvatochromism attributable to an induced intramolecular charge transfer from triphenylamine/carbazole donor to cyano acceptor. …”
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    Vinyl-Linked Cyanocarbazole-Based Emitters: Effect of Conjugation and Terminal Chromophores on the Photophysical and Electroluminescent Properties
  16. 3496
    “…Thus, the co-assembly of l-phenylalanine terminated bolaamphiphile (Bola-F) and the porphyrin containing four hydroxyl groups (tetrakis-5,10,15,20-(4-hydroxyphenyl)porphyrin) can form microtube in methanol and forms fibers/spheres in methanol/water mixture. …”
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    Hierarchical Assembly of l-Phenylalanine-Terminated Bolaamphiphile with Porphyrin Show Tunable Nanostructures and Photocatalytic Properties
  17. 3497
    “…In addition, the RAC/Ssb system plays a crucial role in maintaining the fidelity of translation termination; however, the latter function is poorly understood. …”
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    A dual role of the ribosome-bound chaperones RAC/Ssb in maintaining the fidelity of translation termination
  18. 3498
    “…METHODS: Full colonoscopy, including the terminal ileum, was performed in 60 AS patients and 20 controls, without diarrhoea, to study macroscopic and microscopic lesions. …”
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    The colon and terminal ileum in patients with ankylosing spondylitis and controls in Bangladesh: a macroscopic and microscopic study
  19. 3499
    “…To enhance the thermostability of xylanase PjxA, two mutation strategies in the N-terminal region were examined and then integrated into the xylanase to further improvement. …”
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    Mutagenesis of N-terminal residues confer thermostability on a Penicillium janthinellum MA21601 xylanase
  20. 3500
    “…Teneurin C-terminal associated peptides (TCAPs) are an evolutionarily ancient family of 40- to 41-residue bioactive peptides located on the extracellular end of each of the four teneurin transmembrane proteins. …”
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    Activity of the Carboxy-Terminal Peptide Region of the Teneurins and Its Role in Neuronal Function and Behavior in Mammals
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