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3601
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3602por Chen, Xiaolei, Yang, Zhongmei, Wang, Wenfeng, Qian, Kaiyue, Liu, Mingjie, Wang, Junchao, Wang, Mingzhu“…Here, we report the crystal structure of the N-terminal tandem RRM domains of human RBM45 in complex with single-stranded DNA (ssDNA). …”
Publicado 2021
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3603por Lyčka, Martin, Peska, Vratislav, Demko, Martin, Spyroglou, Ioannis, Kilar, Agata, Fajkus, Jiří, Fojtová, Miloslava“…Over the last years, new methods for the analysis of the length of telomeres have been developed, including those based on PCR or analysis of NGS data. Despite that, terminal restriction fragment (TRF) method remains the gold standard to this day. …”
Publicado 2021
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3604por Chu, Chang, Elitok, Saban, Zeng, Shufei, Xiong, Yingquan, Hocher, Carl-Friedrich, Hasan, Ahmed A., Krämer, Bernhard K., Hocher, Berthold“…Limited data exist comparing the association of either c-terminal FGF23 (cFGF23) or intact FGF23 (iFGF23) in kidney transplant recipients (KTRs) with overall (all-cause) graft loss. …”
Publicado 2021
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3605por Schulig, Lukas, Grabarczyk, Piotr, Geist, Norman, Delin, Martin, Forkel, Hannes, Kulke, Martin, Delcea, Mihaela, Schmidt, Christian A., Link, Andreas“…Here, we report the structural basis for BCL11B–BCL11B interaction mediated by the N-terminal ZF domain. By combining structure prediction algorithms, enhanced sampling molecular dynamics and fluorescence resonance energy transfer (FRET) approaches, we identified amino acid residues indispensable for the formation of the single ZF domain and directly involved in forming the dimer interface. …”
Publicado 2021
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3606por Wang, Siyao, Zhou, Qingqing, Chen, Xiaoping, Luo, Rong-Hua, Li, Yunxue, Liu, Xinliang, Yang, Liu-Meng, Zheng, Yong-Tang, Wang, Ping“…This method offers an efficient and complementary approach to existing strategies for N-terminal modification of proteins.…”
Publicado 2021
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3607“…The purpose of this study is to obtain an overview and analyze the concept of procedural law regarding the implementation of collective agreements with legal certainty in terminating employment in Indonesia. This research is legal research using a statutory approach, a conceptual approach, and a case approach—the collection of material through the literature study method, with primary and secondary legal materials. …”
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3608por Revill, Ann L., Katzell, Alexis, Del Negro, Christopher A., Milsom, William K., Funk, Gregory D.“…Mechanisms underlying burst generation have been investigated for decades, but cellular and synaptic mechanisms responsible for burst termination have received less attention. KCNQ-mediated K(+) currents contribute to burst termination in other systems, and their transcripts are expressed in preBötC neurons. …”
Publicado 2021
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3609
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3610“…We conclude that the C-terminal-most CBM10-3 secures firm binding, with contribution from CBM10-2, which with CBM10-1 also provides spatial flexibility.…”
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3611por Chang, Li-Fang, Lin, Chi-Kang, Wu, Li-Fen, Ho, Ching-Liang, Lu, Yi-Ling, Pan, Hsueh-Hsing“…Using path modeling, this study aimed to explore whether mental adjustment was directly or indirectly related to comprehensive quality of life outcome (CoQoLO) among patients with terminal cancer. We conducted a cross-sectional designed study among patients with terminal cancer who underwent convenience sampling at our northern Taiwan clinic from August 2019 to August 2020. …”
Publicado 2021
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3612“…In an attempt to further refine the reconstitution assay, we have found that chromosomal binding of Xenopus laevis topo IIα is sensitive to buffer conditions and depends on its C-terminal domain (CTD). Enzymological assays using circular DNA substrates supports the idea that topo IIα first resolves inter-chromatid entanglements to drive individualization and then generates intra-chromatid entanglements to promote thickening. …”
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3613por Karoulias, Stylianos-Zafeirios, Pitou, Maria, Papi, Rigini, Lamprou, Paraskevas, Choli-Papadopoulou, Theodora“…In particular, the broad C-terminal region expanding from Val63 to Arg114 as well as its shorter sequence 86-AISMLYLDEN-95 exhibited the highest osteogenic ability for regeneration and reconstruction of bone tissue. …”
Publicado 2021
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3614por Contreras-García, Itzel Jatziri, Gómez-Lira, Gisela, Phillips-Farfán, Bryan Víctor, Pichardo-Macías, Luz Adriana, García-Cruz, Mercedes Edna, Chávez-Pacheco, Juan Luis, Mendoza-Torreblanca, Julieta G.“…Synaptic vesicle protein 2A (SV2A), the target of the antiepileptic drug levetiracetam (LEV), is expressed ubiquitously in all synaptic terminals. Its levels decrease in patients and animal models of epilepsy. …”
Publicado 2021
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3615“…The optimal constructions in accord with previous research and engineering practices for various three-terminal devices are obtained, which confirms the compatibility between the low-dissipation model and endoreversible model and highlights the validity of the application of low-dissipation model for multi-terminal thermodynamic devices. …”
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3616por Landureau, Maud, Redeker, Virginie, Bellande, Tracy, Eyquem, Stéphanie, Melki, Ronald“…However, the N-terminal amino acid residues 1 to 38 of fibrils were exposed to the solvent, while only residues 1 to 18 within fibrils 91 were exposed, and no N-terminal residues within ribbons were solvent-exposed. …”
Publicado 2021
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3617“…To investigate the dynamic localization of Topoisomerase II in live C. elegans we have generated a C-terminally GFP-tagged version of TOP-2 at the endogenous locus. …”
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3618por Waheed, Abdul, Wang, Yan-Ping, Nkurikiyimfura, Oswald, Li, Wen-Yang, Liu, Shi-Ting, Lurwanu, Yahuza, Lu, Guo-Dong, Wang, Zong-Hua, Yang, Li-Na, Zhan, Jiasui“…Frameshifts caused by a single base-pair deletion at the 194th nucleotide position generate two stop codons, truncating almost the entire C-terminal, which is important for effector function and R4 recognition in all sequences. …”
Publicado 2021
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3619por Broughel, Erin M, Hennig, Kelsey, Chu, Rebecca, Parker, Wendy M, Campo-Engelstein, Lisa, Burton-Chase, Allison M“…Data were collected through online surveys and phone interviews; the interview data (n = 55) were analyzed to identify provider terminations and the factors that motivated these decisions. …”
Publicado 2021
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3620por Redzic, Jasmina S., Lee, Eunjeong, Born, Alexandra, Issaian, Aaron, Henen, Morkos A., Nichols, Parker J., Blue, Ashley, Hansen, Kirk C., D'Alessandro, Angelo, Vögeli, Beat, Eisenmesser, Elan Zohar“…To begin addressing the SARS-CoV-2 nucleocapsid protein interactions with both RNA and the host cell along with its dynamic behavior, we have specifically focused on the folded N-terminal domain (NTD) and its flanking regions using nuclear magnetic resonance solution studies. …”
Publicado 2021
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