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Cuidado terminal
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3701por Nemkov, Travis, Kingsley, Paul D., Dzieciatkowska, Monika, Malik, Jeffrey, McGrath, Kathleen E., Hansen, Kirk C., D’Alessandro, Angelo, Palis, JamesEnlace del recurso
Publicado 2022
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3702“…We propose that mitochondria modulate the timing and reliability of neurotransmission in motor nerve terminals during brief AP trains.…”
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3703por Bhatia, Sanil, Spanier, Lukas, Bickel, David, Dienstbier, Niklas, Woloschin, Vitalij, Vogt, Melina, Pols, Henrik, Lungerich, Beate, Reiners, Jens, Aghaallaei, Narges, Diedrich, Daniela, Frieg, Benedikt, Schliehe-Diecks, Julian, Bopp, Bertan, Lang, Franziska, Gopalswamy, Mohanraj, Loschwitz, Jennifer, Bajohgli, Baubak, Skokowa, Julia, Borkhardt, Arndt, Hauer, Julia, Hansen, Finn K., Smits, Sander H. J., Jose, Joachim, Gohlke, Holger, Kurz, Thomas“…In contrast, modulators that interfere with the C-terminal domain (CTD) of Hsp90 do not inflict HSR. …”
Publicado 2022
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3704“…The sncRNAs with other terminal formations such as those with a 5′-hydroxyl end (5′-OH), a 3′-phosphate (3′-P) end, or a 2′,3′-cyclic phosphate end (2′,3′-cP) cannot be efficiently amplified and sequenced by standard RNA-seq. …”
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3705por Suryadevara, Naveenchandra, Shiakolas, Andrea R., VanBlargan, Laura A., Binshtein, Elad, Chen, Rita E., Case, James Brett, Kramer, Kevin J., Armstrong, Erica C., Myers, Luke, Trivette, Andrew, Gainza, Christopher, Nargi, Rachel S., Selverian, Christopher N., Davidson, Edgar, Doranz, Benjamin J., Diaz, Summer M., Handal, Laura S., Carnahan, Robert H., Diamond, Michael S., Georgiev, Ivelin S., Crowe, James E.“…Most SARS-CoV-2 protective antibodies target the receptor-binding domain or a single dominant epitope (“supersite”) on the N-terminal domain (NTD). Using the single B cell technology called linking B cell receptor to antigen specificity through sequencing (LIBRA-Seq), we isolated a large panel of NTD-reactive and SARS-CoV-2–neutralizing antibodies from an individual who had recovered from COVID-19. …”
Publicado 2022
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3706por Xie, Xia, Gan, Tingting, Rao, Bing, Zhang, Weiwei, Panchakshari, Rohit A, Yang, Dingpeng, Ji, Xiong, Cao, Yu, Alt, Frederick W, Meng, Fei‐Long, Hu, Jiazhi“…AID dynamically shuttles between cytoplasm and nucleus, and the majority stays in the cytoplasm due to active nuclear export mediated by its C‐terminal peptide. In immunodeficient‐patient cells expressing mutant AID lacking its C‐terminus, a catalytically active AID‐delC protein accumulates in the nucleus but nevertheless fails to support CSR. …”
Publicado 2022
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3707“…Patients with terminal cancer have different physical symptoms, prognoses, emotional distress, and end-of-life care plans from those receiving aggressive chemotherapy; few studies have assessed healthcare resource use in these patients. …”
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3708por Andersen, Mads Ørbæk, Diederichsen, Søren Zöga, Svendsen, Jesper Hastrup, Carlsen, JørnEnlace del recurso
Publicado 2022
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3709por Riemenschneider, Henrick, Guo, Qiang, Bader, Jakob, Frottin, Frédéric, Farny, Daniel, Kleinberger, Gernot, Haass, Christian, Mann, Matthias, Hartl, F. Ulrich, Baumeister, Wolfgang, Hipp, Mark S, Meissner, Felix, Fernández‐Busnadiego, Rubén, Edbauer, Dieter“…In disease, characteristic C‐terminal fragments of ~25 kDa ("TDP‐25") accumulate in cytoplasmic inclusions. …”
Publicado 2022
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3710“…BACKGROUND: Treatment of superficial venous reflux has been shown to improve ulcer healing time and reduce the risk of ulcer recurrence. Terminal ablation of the reflux source (TIRS) is an alternative to formal endovenous ablation or surgery which can be performed by injecting sclerosant foam into the peri-ulcer plexus of the veins. …”
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3711por D’Uonnolo, Giulia, Reynders, Nathan, Meyrath, Max, Abboud, Dayana, Uchański, Tomasz, Laeremans, Toon, Volkman, Brian F., Janji, Bassam, Hanson, Julien, Szpakowska, Martyna, Chevigné, Andy“…Although the two isoforms differ only by the presence of an N-terminal extension in CXCR3-B, they have been attributed divergent functional effects on cell migration and proliferation. …”
Publicado 2022
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3712por Du, Jie, Zhao, Ping, Wang, Jiazhen, Ma, Sanyuan, Yao, Lunguang, Zhu, Xuwei, Yang, Xinfeng, Zhang, Xian, Sun, Zhenbo, Liang, Shimei, Xing, Dongxu, Duan, Jianping“…The pupal diapause of univoltine Antheraea pernyi hampers sericultural and biotechnological applications, which requires a high eclosion incidence after artificial diapause termination to ensure production of enough eggs. The effect of pupal diapause termination using 20-hydroxyecdysone (20E) on the eclosion incidence has not been well-documented in A. pernyi. …”
Publicado 2022
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3713“…Bromodomain and extra-terminal (BET) proteins are reader proteins that bind to acetylated lysines in histone tails and play a crucial role in regulating gene transcription. …”
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3714por Šede, Megija, Fridmanis, Jēkabs, Otikovs, Martins, Johansson, Jan, Rising, Anna, Kronqvist, Nina, Jaudzems, Kristaps“…The spidroin N-terminal domain (NT) is responsible for high solubility and pH-dependent assembly of spider silk proteins during storage and fiber formation, respectively. …”
Publicado 2022
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3715por Wang, Chenlong, Kang, Huiling, Tan, Ming, Cong, Jingyuan, Su, Dan, Li, Xuemei, Chen, Yutao“…In this study, we provided both phenotypic and structural evidence to show that huNoV DSV and VA115 recognize a group of glycans with terminal galactoses as ligands. First, through glycan array we found that both DSV and VA115 protruding (P) domain proteins bound two oligosaccharides that share common terminal galactoses. …”
Publicado 2022
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3716por Fagerli, Frode Håskjold, Wang, Zhaohui, Grande, Tor, Kaland, Henning, Selbach, Sverre M., Wagner, Nils Peter, Wiik, Kjell“…[Image: see text] Two-dimensional MXenes have shown great promise for many different applications, but in order to fully utilize their potential, control of their termination groups is essential. Here we demonstrate hydrolyzation with a continuous gas flow as a method to remove F-terminations from multilayered V(2)CT(x) particles, in order to prepare nearly F-free and partly bare vanadium carbide MXene. …”
Publicado 2022
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3717“…Our strategy capitalizes on the unique reactivity of an N-terminal cysteine (NCys) with 2-cyanobenzothiazole (CBT) which, in conjugation with another thiol-reactive group, can elicit rapid cyclization between an NCys and an internal cysteine. …”
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3718por Han, Beibei, Tai, Yuxin, Li, Shuping, Shi, Junmei, Wu, Xueqing, Kakeshpour, Tayebeh, Weng, Jianfeng, Cheng, Xianguo, Park, Sunghun, Wu, Qingyu“…AtCAX1 activity is inhibited by its N-terminal regulatory region (NRR), which was initially defined as the sequence between the first two methionines. …”
Publicado 2022
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3719por Wang, Huang, Zhao, Dange, Du, Haibo, Zhai, Xiaoyan, Wu, Shaoxuan, Lin, Lin, Xu, Zhigang, Lu, QingEnlace del recurso
Publicado 2022
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3720“…The results of the research on the mobile terminal equipment and methods of martial arts movement correction in the intelligent sports environment show that the mobile terminal equipment can improve the independent training ability of athletes, and at the same time has a good correction effect on irregular movements.…”
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