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Cuidado terminal
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641“…Here, we report the copper(I)-catalyzed silaboration of terminal allenes to produce multisubstituted allylic boronates embedded with an alkenyl silane structure. …”
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643por Pérez‐Bitrián, Alberto, Alvarez, Santiago, Baya, Miguel, Echeverría, Jorge, Martín, Antonio, Orduna, Jesús, Menjón, Babil“…Since gold is located well beyond the oxo wall, chemical species with terminal Au−N and Au−O units are extremely rare and limited to low coordination numbers. …”
Publicado 2022
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644“…A rhodium‐catalyzed anti‐Markovnikov hydroiodination of aromatic and aliphatic terminal alkynes is reported. Depending on the choice of ligand and substrate, either (E)‐ or (Z)‐configured alkenyl iodides are obtained in high to exclusive isomeric purity. …”
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645por Lee, Si Won“…Considering these issues, I aim to discuss the practical aspects of notifying the patient of the terminal phase of cancer and planning for end-of-life care (i.e., advance care planning). …”
Publicado 2022
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646por Li, Aifang, Wang, Qianfang, Huang, Yu, Hu, Lina, Li, Shuxuan, Wang, Qianqian, Yu, Yangfan, Zhang, Haizhou, Tang, Doris Ying Ying, Show, Pau Loke, Feng, Shuying“…Collectively, EYA would terminate CSBV infection soon, as well as will provide scientific guidance and references to control and manage other viral infections in apiculture.…”
Publicado 2023
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647por Silva, Ana Rute Preis, Bodanezi, Augusto Vanni, Chrun, Emanuely Silva, Lisboa, Mariah Luz, de Camargo, Alessandra R, Munhoz, Etiene Andrade“…Other complications in terminal patients and their treatments still need to have further studying.…”
Publicado 2023
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648por Bogaert, Annelies, Fijalkowska, Daria, Staes, An, Van de Steene, Tessa, Vuylsteke, Marnik, Stadler, Charlotte, Eyckerman, Sven, Spirohn, Kerstin, Hao, Tong, Calderwood, Michael A, Gevaert, Kris“…Alternative translation initiation and alternative splicing may give rise to N-terminal proteoforms, proteins that differ at their N-terminus compared with their canonical counterparts. …”
Publicado 2023
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649por Balka, Katherine R, Venkatraman, Rajan, Saunders, Tahnee L, Shoppee, Angus, Pang, Ee Shan, Magill, Zoe, Homman‐Ludiye, Jihane, Huang, Cheng, Lane, Rachael M, York, Harrison M, Tan, Peck, Schittenhelm, Ralf B, Arumugam, Senthil, Kile, Benjamin T, O'Keeffe, Meredith, De Nardo, Dominic“…Disruption of ESCRT functionality greatly enhanced STING signalling and cytokine production, thus characterising a mechanism controlling effective termination of STING signalling.…”
Publicado 2023
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650por Prabhakar, Arjun, Pavlov, Michael Y, Zhang, Jingji, Indrisiunaite, Gabriele, Wang, Jinfan, Lawson, Michael R, Ehrenberg, Måns, Puglisi, Joseph D“…In bacteria, release of newly synthesized proteins from ribosomes during translation termination is catalyzed by class-I release factors (RFs) RF1 or RF2, reading UAA and UAG or UAA and UGA codons, respectively. …”
Publicado 2023
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651por Li, Shan, Li, Juan, Shi, Wenjing, Nie, Ziyan, Zhang, Shasha, Ma, Fengdie, Hu, Jun, Chen, Jianjun, Li, Peiqiang, Xie, Xiaodong“…Further research is still needed to deeply understand the mechanism of eukaryotic cell termination and drug-induced PTC readthrough so that patients can achieve the greatest benefit from the various TRID treatments.…”
Publicado 2023
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652por Talavera, Laura, Freund, Robert R. A., Zhang, Huihui, Wakeling, Matthew, Jensen, Mara, Martin, Ruben“…[Image: see text] Herein, we disclose a Ni-catalyzed 1,1-difunctionalization of unactivated terminal alkenes that enables the incorporation of two different heteroatom motifs across an olefin backbone, thus streamlining the access to α-aminoboronic acid derivatives from simple precursors. …”
Publicado 2023
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653“…This region is defined by multiple genomic terminator (ter) sites, which, if bound by specific terminator proteins, form unidirectional fork barriers. …”
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654“…Herein, we determined the crystal structure of the Sus scrofa SLFN11 N-terminal domain (NTD) to 2.69 Å resolution. sSLFN11-NTD is a pincer-shaped molecule that shares an overall fold with other SLFN-NTDs but exhibits distinct biochemical characteristics. sSLFN11-NTD is a potent RNase cleaving type I and II tRNAs and rRNAs, and with preference to type II tRNAs. …”
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656por Löwe, Pawel, Wünsche, Marius A., Purtscher, Felix R. S., Gamper, Jakob, Hofer, Thomas S., Wilm, Lukas F. B., Röthel, Maike B., Dielmann, Fabian“…We herein report a synthetic approach to monosubstituted phosphinocarbenes via deprotonation of hitherto unknown diprotic terminal methylene phosphonium ions. Two methylene phosphonium salts bearing bulky N-heterocyclic imine substituents at the phosphorus atom were isolated and fully characterized. …”
Publicado 2023
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657“…Hence, encountering a non-treated and terminal-period patient is rare. Our case was unique because it showed the clinical picture and atypical radiological distribution of a 20-year-old, terminally ill untreated female patient. …”
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658por Eyisoy, Ömer Gökhan, Özgökçe, Çağdaş, Uygur, Lütfiye, Eriç Özdemir, Mucize, Taşdemir, Ümit, Öcal, Aydın, Demirci, Oya“…The number of terminations with fetal indications performed after 22 weeks were 148 (41%) and 11 (7.4%) cases of these late terminations of pregnancy were anomalies expected to be diagnosed in the first trimester. …”
Publicado 2023
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659“…In addition, we investigated the effects of terminator–promoter combinations on gene expression and found that the combinations of promoters and terminators resulted in a 326-fold difference between the strongest and weakest performance, as reflected in reporter gene expression. …”
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660por Sierra, Alicia Armella, Loureiro, María Eugenia, Esperante, Sebastián, Borkosky, Silvia Susana, Gallo, Giovanna L., de Prat Gay, Gonzalo, Lopez, Nora“…Here, we report that the C-terminal domain (CTD) of the attenuated Candid#1 strain of the JUNV NP can be purified as a stable soluble form with a secondary structure in line with known NP structures from other mammarenaviruses. …”
Publicado 2023
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