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Cuidado terminal
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Historia
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Enfermedad terminal en niños
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681
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682Publicado 1975“…The mouse thymus contains two forms of terminal deoxynucleotidyl transferase (TdT) which are distinguishable by the salt concentration necessary to elute them from a phosphocellulose column, by their distrubtion among the thymocyte subpopulations, and by their sensitivity to cortisone treatment. …”
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683Publicado 1994“…Basonuclin is not a cell cycle marker but is likely instead to be a regulatory molecular whose presence in the keratinocyte is linked to the maintenance of proliferative capacity and prevention of terminal differentiation.…”
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684“…Previous studies suggested that the cytoplasmic COOH-terminal portions of inward rectifier K channels could contribute significant resistance barriers to ion flow. …”
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685por Večerek, Branislav, Rajkowitsch, Lukas, Sonnleitner, Elisabeth, Schroeder, Renée, Bläsi, Udo“…The Hfq proteins of different bacteria consist of an evolutionarily conserved core, whereas there is considerable variation at the C-terminus, with the γ- and β-proteobacteria possessing the longest C-terminal extension. Using different model systems, we show that a C-terminally truncated variant of Hfq (Hfq(65)), comprising the conserved hexameric core of Hfq, is defective in auto- and riboregulation. …”
Publicado 2008
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686“…Transcriptional termination of mammalian RNA polymerase II (Pol II) is an essential but little-understood step in protein-coding gene expression. …”
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687
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688por Zybailov, Boris, Rutschow, Heidi, Friso, Giulia, Rudella, Andrea, Emanuelsson, Olof, Sun, Qi, van Wijk, Klaas J.“…We highlight the abundance of 48 stromal proteins involved in post-translational proteome homeostasis (including aminopeptidases, proteases, deformylases, chaperones, protein sorting components) and discuss the biological implications. N-terminal modifications were identified for a subset of nuclear- and chloroplast-encoded proteins and a novel N-terminal acetylation motif was discovered. …”
Publicado 2008
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689
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690
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691
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692“…BACKGROUND: Premature termination codons (PTCs) cause mRNA degradation or a truncated protein and thereby contribute to the transcriptome and proteome divergence between species. …”
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693por Parcellier, Arnaud, Tintignac, Lionel A., Zhuravleva, Elena, Dummler, Bettina, Brazil, Derek P., Hynx, Debby, Cron, Peter, Schenk, Susanne, Olivieri, Vesna, Hemmings, Brian A.“…We showed recently that the Carboxy-Terminal Modulator Protein (CTMP) is a mitochondrial protein that may be released into the cytosol under apoptotic conditions. …”
Publicado 2009
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694“…This study reports the presence of Syt IV on both dense-core and microvesicles in posterior pituitary nerve terminals. In terminals from Syt IV knock-out mice compared to wild-type, low Ca(2+) entry triggered more exocytosis, high Ca(2+) entry triggered less exocytosis, and endocytosis was accelerated. …”
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695“…Interestingly, ten of these C-terminal splice variants have been shown to display dominant-negative activity on the transactivational properties of their canonical equivalent. …”
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696por Arnesen, Thomas“…Protein N-terminal acetylation is a very common modification, but has during the past decades received relatively little attention. …”
Publicado 2009
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697por Starheim, Kristian K, Gromyko, Darina, Velde, Rolf, Varhaug, Jan Erik, Arnesen, Thomas“…Protein N(α)-terminal acetylation is one of the most common protein modifications in eukaryotic cells, occurring on approximately 80% of soluble human proteins. …”
Publicado 2009
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698
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699por Mielgo, Ainhoa, Torres, Vicente A., Schmid, Michael C., Graf, Ryon, Zeitlin, Samantha G., Lee, Pedro, Shields, David J., Barbero, Simone, Jamora, Colin, Stupack, Dwayne G.“…Most of these functions are attributed to the catalytic domain, however, the amino-terminal death effector domains (DED)s, which belong to the death domain superfamily of proteins, can also play key roles during development. …”
Publicado 2009
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700“…Transcription termination of RNA polymerase II (Pol II) on protein-coding genes in S. cerevisiae relies on pA site recognition by 3′ end processing factors. …”
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