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  1. 85961
    “…Overall drug survival of (low-dose) isotretinoin (n = 66) at 12 and 24 months was 44.2% and 15.5%, respectively. Termination of treatment was mostly due to ineffectiveness (26%). …”
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    Drug Survival of Oral Retinoids in Hidradenitis Suppurativa: A Real-Life Cohort Study
  2. 85962
    “…RESULTS: After an interim analysis, the study was terminated (delayed and slow accrual). Until 60 Gy, grade ≥ 2 dermatitis rates were 72% with vs. 82% without app (p = 0.38), grade ≥ 3 dermatitis rates 20% vs. 11% (p = 0.45). …”
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    Impact of a mobile application (reminder app) on acute toxicity during radiotherapy of head-and-neck cancer – results of a randomized phase III trial (RAREST-02)
  3. 85963
    “…RESULTS: We explored yeast promoters and terminators to tune the expression levels of the starch-biosynthesis machinery from Arabidopsis thaliana. …”
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    Tuning heterologous glucan biosynthesis in yeast to understand and exploit plant starch diversity
  4. 85964
    “…Importantly, co-immunofluorescence demonstrated that Raptor deficiency induced SCs dedifferentiation into a progenitor state; the Raptor-mutant gonads showed some ovarian somatic cell features, accompanied by enhanced female steroidogenesis and elevated estrogen levels, yet the zona pellucida 3 (ZP3)-positive terminally feminized oocytes were not observed. In vitro experiments with primary SCs suggested that Raptor is likely involved in the fibroblast growth factor 9 (FGF9)-induced formation of cell junctions among SCs. …”
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    Loss of Raptor induces Sertoli cells into an undifferentiated state in mice
  5. 85965
    “…This differential role depends on their ability to confer different properties to adrenergic α(2A) receptor (α(2A)R)-D(4)R heteromers and dopamine D(2) receptor (D(2)R)-D(4)R heteromers, preferentially localized in the perisomatic region of the frontal cortical pyramidal neuron and its striatal terminals, respectively. We also review the evidence to support the D(4)R as a therapeutic target for ADHD and other impulse-control disorders, as well as for restless legs syndrome.…”
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    Functional and pharmacological role of the dopamine D(4) receptor and its polymorphic variants
  6. 85966
    “…Among the patients with a tumor size > 4 cm (up to 5 cm), three patients who wished to preserve fertility accepted RT following neoadjuvant chemotherapy The pregnancy outcomes were as follows: 8 cases (47.06%) out of 17 cases who attempting pregnancy conceived 12 times.First-trimester abortion and the voluntary abandonment of pregnancy occurred in 4 cases (33.33%), respectively, one patient performed deliberate termination at 24 weeks of gestation. Second-trimester abortion occurred in three cases (25.0%) for chorioamnionitis. …”
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    The oncological and obstetric results of radical trachelectomy as a fertility-sparing therapy in early-stage cervical cancer patients
  7. 85967
    “…EOLd before the onset of AE was significantly associated with the early use of opioids. CONCLUSION: In terminally ill AE-IPF patients, opioids are usually administered when the recovery is deemed impossible, and EOLd are rarely held before the onset of AE. …”
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    End-of-life care for idiopathic pulmonary fibrosis patients with acute exacerbation
  8. 85968
    “…Assessment is at baseline, directly after the first and ninth training session, after the last training session (post training), and 1 week and 3 months after termination of the training (follow-up). DISCUSSION: If effective, a tACS-VST rehabilitation program could be implemented as a treatment option for VSN. …”
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    Study protocol of transcranial electrical stimulation at alpha frequency applied during rehabilitation: A randomized controlled trial in chronic stroke patients with visuospatial neglect
  9. 85969
    “…At the time of intervention termination, EAT-10 scores were lower in the Exp group than in the Con group (p = 0.005). …”
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    A Novel Balloon Catheter-based Dilation Intervention for Patients with Cricopharyngeus Achalasia After Stroke: A Randomized Study
  10. 85970
    “…RESULTS: We recruited 188 participants (94 per group); 112 (59.6%) were men; the median (IQR) age was 52 (44–64) years. The study was terminated early due to a significant reduction in the primary outcome in the treatment arm and increased difficulty with recruitment. …”
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    Pyridostigmine reduces mortality of patients with severe SARS-CoV-2 infection: A phase 2/3 randomized controlled trial
  11. 85971
    “…They will be asked to provide a stool sample for microbiome analysis and will undergo continuous glucose monitoring for 2 weeks, at the initiation and termination of the intervention period. Microbiome composition data will be used to tailor personal dietary recommendations. …”
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    BREAst Cancer Personalised NuTrition (BREACPNT): dietary intervention in breast cancer survivors treated with endocrine therapy – a protocol for a randomised clinical trial
  12. 85972
    “…Fundamentally, airports have significant fixed costs, and it has been especially challenging to run terminals and operations with little or no revenue from conventional channels. …”
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    Airport business models and the COVID-19 pandemic: An exploration of the UK case study
  13. 85973
    “…Furthermore, neonates show defects in terminating inflammation. The immunological causes for the increased susceptibility to infection and the prolonged inflammatory response are still incompletely understood. …”
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    Group B streptococci infection model shows decreased regulatory capacity of cord blood cells
  14. 85974
    “…This should impact the clinical decision making in an oncology center providing quality care to the terminally ill patients.…”
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    Audit of In-Hospital Mortality from a Medical Oncology and Hemato-Oncology Center with the Emphasis on Best Supportive Care
  15. 85975
    “…A loss of 137 bp at the 3′ end of NIPBL exon 40 was detected, which potentially altered the open reading frame by inserting multiple premature termination codons. Quantitative real-time PCR analysis showed that the ratio of the transcription level of the full-length transcript to that of the altered short transcript in the patient was 5:1, instead of 1:1. …”
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    Case report: A novel heterozygous synonymous variant in deep exon region of NIPBL gene generating a non-canonical splice donor in a patient with cornelia de lange syndrome
  16. 85976
    “…Overall, nuanced attitudes regarding vaccine and booster mandates were expressed; many supported mandates to protect their patients’ health, others emphasized personal autonomy, while some were against mandates if job termination was the consequence of declining vaccines. …”
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    Healthcare workers’ attitudes on mandates, incentives, and strategies to improve COVID-19 vaccine uptake: A mixed methods study
  17. 85977
    “…OBJECTIVE: To evaluate the impact of rheumatoid arthritis (RA) and methotrexate (MTX) on the probability of becoming pregnant, pregnancy losses, elective termination of pregnancy (TOP) and congenital malformations. …”
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    Impact of rheumatoid arthritis and methotrexate on pregnancy outcomes: retrospective cohort study of the Italian Society for Rheumatology
  18. 85978
    “…Photographic documentation of the ears was performed before treatment, at treatment termination, and 12 months after treatment to evaluate treatment efficacy and relapse. …”
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    One-Year Outcomes of Ear Molding for Infants with Constricted Ear
  19. 85979
    “…Regeneration of the neuromuscular junction (NMJ) leverages on extensive exchange of factors released from motor axon terminals (MATs), muscle fibers and perisynaptic Schwann cells (PSCs), among which hydrogen peroxide (H(2)O(2)) is a major pro-regenerative signal. …”
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    Hydrogen peroxide induced by nerve injury promotes axon regeneration via connective tissue growth factor
  20. 85980
    “…Factors such as defining major CAs, proportion of terminations of pregnancy for foetal anomaly, source of mortality data and linkage methods are important to consider in the design of future studies and in the interpretation of the results on survival of children with CAs.…”
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    Temporal and geographical variations in survival of children born with congenital anomalies in Europe: A multi‐registry cohort study
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