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  1. 86161
    “…In vivo imaging studies indicate an increased presynaptic dopamine synthesis capacity in striatal terminals and cell bodies in the midbrain in schizophrenia; however, measures of the dopamine-synthesising enzyme, tyrosine hydroxylase (TH), have not identified consistent changes. …”
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    Putative presynaptic dopamine dysregulation in schizophrenia is supported by molecular evidence from post-mortem human midbrain
  2. 86162
    “…The results showed that EM-2-IR fibers and terminals were sparsely observed in lamina IX and they formed symmetric synaptic connections with the motoneurons within lamina IX of the spinal ventral horn. …”
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    Endomorphin-2 Decreases Excitatory Synaptic Transmission in the Spinal Ventral Horn of the Rat
  3. 86163
    “…Because of withdrawal of funding after insufficient recruitment, enrolment was terminated early. At 30 days, the rate of any stroke or death in the intention-to-treat population was 12/65 (18.5%) in patients receiving synchronous carotid endarterectomy+CABG as compared with 6/62 (9.7%) in patients receiving isolated CABG (absolute risk reduction, 8.8%; 95% confidence interval, −3.2% to 20.8%; P(WALD)=0.12). …”
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    Safety of Simultaneous Coronary Artery Bypass Grafting and Carotid Endarterectomy Versus Isolated Coronary Artery Bypass Grafting: A Randomized Clinical Trial
  4. 86164
    “…Given the requirement of intensive human capital, poor quality control of surgical services, and the overall costs of the program, hospital leadership decided to terminate the referral coordination program and continue to build local surgical capacity. …”
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    Surgical referral coordination from a first-level hospital: a prospective case study from rural Nepal
  5. 86165
    “…The primary endpoint for analysis was the rate of Helicobacter pylori eradication as defined by either a negative 13C-urea breath-test, or stool antigen test, 4–16 weeks after treatment assessed under the non-inferiority hypothesis. The trial was terminated prematurely due to low recruitment rates. …”
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    Efficacy and safety of sequential versus quadruple therapy as second-line treatment for helicobacter pylori infection—A randomized controlled trial
  6. 86166
    “…Women with live births as teenagers experienced significantly fewer years of schooling compared to their counterparts who terminated their pregnancies. Also, women with miscarriages and stillbirths exhibited levels similar to those who gave birth. …”
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    Is a woman’s first pregnancy outcome related to her years of schooling? An assessment of women’s adolescent pregnancy outcomes and subsequent educational attainment in Ghana
  7. 86167
    “…BACKGROUND: The presence of vertebral fractures affect variations in the termination level of conus medullaris (TLCM) and alter neurological findings. …”
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    Reduction of vertebral height with fragility vertebral fractures can induce variety of neurological deterioration
  8. 86168
    “…The principles include humanism, pragmatism, individualism, autonomy, incrementalism, and accountability without termination. For each of these principles, we present a definition, a description of how healthcare providers can deliver interventions informed by the principle, and examples of how each principle may be applied in the healthcare setting. …”
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    Harm reduction principles for healthcare settings
  9. 86169
    “…In both T-cell subpopulations, a shift mainly from naive T cells among peripheral blood lymphocytes toward an effector memory and terminally differentiated subtype predominance in nasal polyps was observed. …”
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    Characterization of T-cell subpopulations in patients with chronic rhinosinusitis with nasal polyposis
  10. 86170
    “…APs observed prior to termination of the protocol showed lower (dV/dt)(max) and longer AP latencies, but indistinguishable APD(90) and RMPs in arrhythmic compared to those in non-arrhythmic hearts. …”
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    Effects of ageing on pro-arrhythmic ventricular phenotypes in incrementally paced murine Pgc-1β(−/−) hearts
  11. 86171
    “…Cas9 and gRNA expression cassettes were reconstituted to combat Cas9 toxicity and facilitate effective termination of gRNA transcription. Co-transformation of Cas9 and gRNA expression plasmids was exploited to overcome high-frequency mutation of cas9, allowing not only highly efficient gene deletion and insertion with plasmid-borne editing templates (efficiencies up to 60.0 and 62.5%, respectively) but also simple and time-saving operation. …”
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    Development of a CRISPR/Cas9 genome editing toolbox for Corynebacterium glutamicum
  12. 86172
    “…After this time-point, the animals were terminally anesthetized, and the maxillae were removed for morphometric and histological analyzes (HE). …”
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    Stemodia maritima L. Extract Decreases Inflammation, Oxidative Stress, and Alveolar Bone Loss in an Experimental Periodontitis Rat Model
  13. 86173
    “…The mechanism is relevant to the initial stages of oncogenic transformation in terminally differentiated cells, when recombination may lead to the LOH exposing recessive mutations induced by APOBECs in cell’s history and to acquisition of new mutations near original break.…”
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    Recombination Is Responsible for the Increased Recovery of Drug-Resistant Mutants with Hypermutated Genomes in Resting Yeast Diploids Expressing APOBEC Deaminases
  14. 86174
    “…BACKGROUND: About 11% of all human genetic diseases are caused by nonsense mutations that generate premature translation termination codons (PTCs) in messenger RNAs (mRNA). …”
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    Antisense suppression of the nonsense mediated decay factor Upf3b as a potential treatment for diseases caused by nonsense mutations
  15. 86175
    “…RESULTS: SRH nurses indicated that they are experiencing challenges with the concept and practice of termination of pregnancy. They explained that this practice contradicted their opposing beliefs and values. …”
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    Healthcare workers’ beliefs, motivations and behaviours affecting adequate provision of sexual and reproductive healthcare services to adolescents in Cape Town, South Africa: a qualitative study
  16. 86176
    “…This process could activate the trigeminal nerve terminals that innervate vascular walls. As a consequence, there is activation of sensory nerve endings at the level of hard vessels in the meninges, with release of pro-inflammatory peptides (e.g., substance P and CGRP). …”
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    Non-Rapid Eye Movement Sleep Parasomnias and Migraine: A Role of Orexinergic Projections
  17. 86177
    “…PARTICIPANTS: 195 patients, exclusion criteria: under 18 years old, patients with a health status not allowing a meaningful communication (eg, delirium, acute psychosis, advanced dementia, aphasia, clouded consciousness state), palliative or terminally ill patients. METHODS: Twenty-seven risk factors for the development of DRPs, identified in a previous study, provided the basis of the self-assessment questionnaire, the Drug-Associated Risk Tool (DART). …”
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    Drug-Associated Risk Tool: development and validation of a self-assessment questionnaire to screen for hospitalised patients at risk for drug-related problems
  18. 86178
    “…RESULTS: Of the 17 patients, 10 (58.5%) underwent surgical treatment (7 laparoscopic cornual resection, and 3 laparotomy); and 3 cases simultaneously terminated the intrauterine pregnancy by suction evacuation. …”
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    Management and obstetric outcomes of 17 heterotopic interstitial pregnancies
  19. 86179
    “…However, a subset of patients experience immune-related adverse events (irAEs), which can be severe and result in treatment termination. To date, no biomarker exists that can predict development of irAEs. …”
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    Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors
  20. 86180
    “…OBJECTIVES: To describe the implementation of a trigger tool in Sweden and present the national incidence of adverse events (AEs) over a 4-year period during which an ongoing national patient safety initiative was terminated. DESIGN: Cohort study using retrospective record review based on a trigger tool methodology. …”
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    Incidence of adverse events in Sweden during 2013–2016: a cohort study describing the implementation of a national trigger tool
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