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86181por Skowron, Piotr M., Kropinski, Andrew M., Zebrowska, Joanna, Janus, Lukasz, Szemiako, Kasjan, Czajkowska, Edyta, Maciejewska, Natalia, Skowron, Malgorzata, Łoś, Joanna, Łoś, Marcin, Zylicz-Stachula, Agnieszka“…In addition, ten putative rho-independent terminators were detected. Because the genome sequence shows essentially no similarity to any previously characterised bacteriophage, TP-84 should be considered a new species in an undefined genus within the Siphoviridae family. …”
Publicado 2018
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86182“…The amplicons were sequenced in both directions with the *BigDye Terminator Cycle Sequencing Ready Reaction Kit according to the manufacturer's protocols. …”
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86183por Gruca, Thomas S., Hottel, Wesley J., Comstock, Janine, Olson, Anna, Rosenthal, Gary E.“…Women had more favorable attitudes about participants being treated like “guinea pigs” (RR for men, 0.84, 95% CI, 0.73–0.98) and clinical trials being associated with terminally ill patients (RR for men, 0.93, 95% CI, 0.86–1.00). …”
Publicado 2018
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86184por Bossu, Alexandre, Houtman, Marien J C, Meijborg, Veronique M F, Varkevisser, Rosanne, Beekman, Henriette D M, Dunnink, Albert, de Bakker, Jacques M T, Mollova, Nevena, Rajamani, Sridharan, Belardinelli, Luiz, van der Heyden, Marcel A G, Vos, Marc A“…CONCLUSION AND IMPLICATIONS: GS967 terminated all dofetilide‐induced TdP without completely suppressing EADs and sEB in vitro and in vivo, respectively. …”
Publicado 2018
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86185por Given, Joanne E, Loane, Maria, Garne, Ester, Addor, Marie-Claude, Bakker, Marian, Bertaut-Nativel, Bénédicte, Gatt, Miriam, Klungsoyr, Kari, Lelong, Nathalie, Morgan, Margery, Neville, Amanda J, Pierini, Anna, Rissmann, Anke, Dolk, Helen“…PARTICIPANTS: 50 167 babies affected by congenital anomaly (41 242 non-genetic and 8925 genetic) including live births, fetal deaths from 20 weeks’ gestation, and terminations of pregnancy for fetal anomaly. MAIN OUTCOME MEASURE: Odds ratios adjusted for maternal age, registry, multiple birth, and maternal diabetes status. …”
Publicado 2018
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86186por Barrett, John A., Cai, Hongliang, Miao, John, Khare, Pranay D., Gonzalez, Paul, Dalsing-Hernandez, Jessica, Sharma, Geeta, Chan, Tim, Cooper, Laurence J.N, Lebel, Francois“…We have demonstrated that this therapy induced localized controlled production of IL-12 which correlates with an increase in tumor-infiltrating lymphocytes (TILs) leading to the desired biologic response of tumor growth inhibition and regression. At day 85 (study termination), 65% of the animals that received veledimex at 10 or 30 mg/m(2)/day were alive and tumor free. …”
Publicado 2018
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86187por Richards, Cynthia, Iosifescu, Dan V., Mago, Rajnish, Sarkis, Elias, Geibel, Brooke, Dauphin, Matthew, McIntyre, Roger S., Weisler, Richard, Brawman-Mintzer, Olga, Gu, Joan, Madhoo, Manisha“…FINDINGS/RESULTS: All 3 antecedent studies failed to meet the prespecified primary efficacy endpoint, so this open-label study was terminated early. Headache (15.5% [241/1559]), dry mouth (13.6% [212/1559]), insomnia (13.1% [204/1559]), and decreased appetite (12.1% [189/1559]) were the most frequently reported treatment-emergent adverse events. …”
Publicado 2018
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86188“…BACKGROUND: The transitioning of young patients from child and adolescent to adult mental health services when indicated often results in the interruption or termination of service. The personal views of young service users on current clinical practice are a valuable contribution that can help to identify service gaps. …”
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86189“…The patient received gemcitabine plus cisplatin initially, but the treatment was terminated due to toxicity. The patient was then switched to treatment with S-1 alone. …”
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86190por Mostacci, Barbara, Bisulli, Francesca, Poluzzi, Elisabetta, Cocchi, Guido, Piccinni, Carlo, Curti, Alessandra, Simonazzi, Giuliana, Astolfi, Gianni, Rizzo, Nicola, Zenesini, Corrado, D’Alessandro, Roberto, Tinuper, Paolo“…OBJECTIVES: To assess the prevalence of antiepileptic drug (AED) exposure in pregnant women and the comparative risk of terminations of pregnancy (TOPs), spontaneous abortions, stillbirths, major birth defects (MBDs), neonatal distress and small for gestational age (SGA) infants following intrauterine AED exposure in the Emilia Romagna region, Italy (4 459 246 inhabitants on 31 December 2011). …”
Publicado 2018
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86191por Sandborn, William J, Bhandari, Bal R, Randall, Charles, Younes, Ziad H, Romanczyk, Tomasz, Xin, Yan, Wendt, Emily, Chai, Hao, McKevitt, Matt, Zhao, Sally, Sundy, John S, Keshav, Satish, Danese, Silvio“…The phase 2/3 trial met prespecified futility criteria and was terminated before completion. This study describes results from the 8-week induction phase. …”
Publicado 2018
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86192“…In both cases, the parents (a 36-year-old woman of Mauritanian ethnicity and a non-consanguineous partner of Nepalese descent, and a 31-year-old Caucasian woman and non-consanguineous Caucasian partner) elected to terminate their pregnancies and made unremarkable recoveries. …”
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86193por Komatsu, Takashi, Kunugita, Fusanori, Ozawa, Mahito, Satoh, Yoshihiro, Yoshizawa, Reisuke, Owada, Shingen, Sawa, Youhei, Morino, Yoshihiro, Nakamura, Motoyuki“…Paroxysmal AF was defined as episodes that terminated spontaneously within 7 days, while chronic AF was defined as longstanding AF that was refractory to cardioversion for 12 months or longer. …”
Publicado 2018
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86194“…Acetylcholinesterases (AChEs) are essential for the hydrolysis of the neurotransmitter acetylcholine and play crucial roles in the termination of neurotransmission. AChEs are encoded by the ace genes. …”
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86195por Verver, Daniëlle, Oude Ophuis, Charlotte M. C., Koppert, Lisa B., de Monyé, Cécile, van Deurzen, Carolien H. M., Koljenović, Senada, Bruining, Annemarie, van der Hiel, Bernies, ter Meulen, Sylvia, van Akkooi, Alexander C. J., Verhoef, Cornelis, Grünhagen, Dirk J.“…RESULTS: Accrual was terminated early following an unplanned interim analysis indicating that a FNAC sensitivity of at least 80% could not be achieved. …”
Publicado 2018
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86196por Gerasimenko, Yury, Sayenko, Dimitry, Gad, Parag, Kozesnik, Justin, Moshonkina, Tatiana, Grishin, Aleksandr, Pukhov, Aleksandr, Moiseev, Sergey, Gorodnichev, Ruslan, Selionov, Victor, Kozlovskaya, Inessa, Edgerton, V. Reggie“…We observed that at the same intensity level of transcutaneous electrical spinal cord stimulation (tSCS), the presence or absence of visualizing a stepping-like movement of a stick figure immediately initiated or terminated the tSCS-induced rhythmic stepping motion, respectively. …”
Publicado 2018
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86197por Russo, Francesca Maria, Benachi, Alexandra, Van Mieghem, Tim, De Hoon, Jan, Van Calsteren, Kristel, Annaert, Pieter, Tréluyer, Jean-Marc, Allegaert, Karel, Deprest, Jan“…In sub-study 1, a single dose of the investigational product will be administered to women undergoing termination of pregnancy, and maternal and fetal blood samples will be collected for determination of sildenafil concentrations. …”
Publicado 2018
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86198por Kentepozidis, Nikolaos, Economopoulou, Panagiota, Liontos, Michael, Kotsakis, Athanasios, Boukovinas, Ioannis, Vardakis, Nikolaos, Kontopodis, Emmanouil, Prinarakis, Efthimios, Skaltsi, Teressa, Souglakos, John, Georgoulias, Vassilis“…However, the study failed to meet its primary endpoint and was terminated prematurely due to futility.…”
Publicado 2018
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86199por Yamanishi, Tadashi, Koizumi, Hidehiko, Navarro, Marco A., Milescu, Lorin S., Smith, Jeffrey C.“…The slow and cumulative inactivation of I(NaP) during the burst active phase controls burst duration and termination, while the slow recovery from inactivation controls the duration of the interburst interval. …”
Publicado 2018
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86200“…All births at 20 complete gestational weeks, including live births, stillbirths, and pregnancy terminations, and all NTDs, regardless of gestational age, were recorded. …”
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