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86721por Wang, Hua-Ling, Yang, Jiao, Boykin, Laura M, Zhao, Qiong-Yi, Li, Qian, Wang, Xiao-Wei, Liu, Shu-Sheng“…In addition, combining the transcriptome with the sequence alignment data, the possible termination site of some PCGs were defined. Our analyses also revealed that atp6 and atp8, nd4 and nd4l, nd6 and cytb were found on the same cistronic transcripts, whereas the other mature mitochondrial transcripts were monocistronic. …”
Publicado 2013
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86722por Michailidis, Eleftherios, Ryan, Emily M, Hachiya, Atsuko, Kirby, Karen A, Marchand, Bruno, Leslie, Maxwell D, Huber, Andrew D, Ong, Yee T, Jackson, Jacob C, Singh, Kamalendra, Kodama, Eiichi N, Mitsuya, Hiroaki, Parniak, Michael A, Sarafianos, Stefan G“…EFdA acts primarily as a chain terminator by blocking translocation following its incorporation into the nascent DNA chain. …”
Publicado 2013
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86723por Schiffels, Johannes, Pinkenburg, Olaf, Schelden, Maximilian, Aboulnaga, El-Hussiny A. A., Baumann, Marcus E. M., Selmer, Thorsten“…Using the novel methodology, genes are equipped with individual promoters and terminators and subsequently assembled. The resulting multiple gene cassettes may either be placed in one vector or alternatively distributed among a set of compatible plasmids. …”
Publicado 2013
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86724por Oliver-Williams, Clare, Fleming, Michael, Monteath, Kirsten, Wood, Angela M., Smith, Gordon C. S.“…BACKGROUND: Numerous studies have demonstrated that therapeutic termination of pregnancy (abortion) is associated with an increased risk of subsequent preterm birth. …”
Publicado 2013
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86725por Desai, Meghna, Phillips-Howard, Penelope A., Odhiambo, Frank O., Katana, Abraham, Ouma, Peter, Hamel, Mary J., Omoto, Jackton, Macharia, Sheila, van Eijk, Annemieke, Ogwang, Sheila, Slutsker, Laurence, Laserson, Kayla F.“…WHO ICD definition of PR mortality was used: “the death of a woman while pregnant or within 42 days of termination of pregnancy, irrespective of the cause of death”. …”
Publicado 2013
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86726por Walsh, Scott R, Linnerth-Petrik, Nicolle M, Yu, Darrick L, Foster, Robert A, Menzies, Paula I, Diaz-Méndez, Andrés, Chalmers, Heather J, Wootton, Sarah K“…At 45 wpi, when the study was terminated, none of the remaining infected sheep showed evidence of tumors either by computed tomography or post-mortem examination. …”
Publicado 2013
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86727por Douvaras, Panagiotis, Mort, Richard L., Edwards, Dominic, Ramaesh, Kanna, Dhillon, Baljean, Morley, Steven D., Hill, Robert E., West, John D.“…It seems likely that Pax6(+/−) LRCs are not exclusively stem cells and some may be terminally differentiated CD31-positive blood vessel cells, which invade the Pax6(+/−) cornea. …”
Publicado 2013
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86728por Park, Yae Min, Lee, Hyun Soo, Lim, Ra Seung, Choi, Jong-Il, Lim, Hong Euy, Park, Sang Weon, Choi, In Suck, Kim, Young-Hoon“…Single high energy (biphasic 150-200 J) external defibrillation was successful in all patients, except in two, who spontaneously terminated VF. The procedure was uneventfully completed in all patients. …”
Publicado 2013
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86729por Dzieran, Johanna, Fabian, Jasmin, Feng, Teng, Coulouarn, Cédric, Ilkavets, Iryna, Kyselova, Anastasia, Breuhahn, Kai, Dooley, Steven, Meindl-Beinker, Nadja M.“…Inhibitory linker phosphorylation, as in HCC-T, may disrupt C-terminally phosphorylated Smad3 function. In summary, we assort 10 HCC cell lines in at least two clusters with respect to TGF-β sensitivity. …”
Publicado 2013
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86730por Tsumagari, Koji, Baribault, Carl, Terragni, Jolyon, Chandra, Sruti, Renshaw, Chloe, Sun, Zhiyi, Song, Lingyun, Crawford, Gregory E, Pradhan, Sriharsa, Lacey, Michelle, Ehrlich, Melanie“…Myogenic hypermethylation might also affect the relative abundance of different RNA isoforms, facilitate transcription termination, help stop the spread of activation-associated chromatin domains and stabilize repressive chromatin structures.…”
Publicado 2013
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86731“…MAIDS and LP-BM5 viral load were assessed at termination. RESULTS: As expected, IDO was un-inducible in B6.IDO−/− during LP-BM5 infection. …”
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86732por Horani, Amjad, Brody, Steven L., Ferkol, Thomas W., Shoseyov, David, Wasserman, Mollie G., Ta-shma, Asaf, Wilson, Kate S., Bayly, Philip V., Amirav, Israel, Cohen-Cymberknoh, Malena, Dutcher, Susan K., Elpeleg, Orly, Kerem, Eitan“…RESULTS: A single novel mutation in CCDC65, which created a termination codon at position 293, was identified in a subject with typical clinical features of PCD. …”
Publicado 2013
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86733por Rocha, Mariana C., Pousinha, Paula A., Correia, Alexandra M., Sebastião, Ana M., Ribeiro, Joaquim A.“…SOD1(G93A) mice presented a higher frequency of GMEPPs, suggestive of intracellular Ca(2+) deregulation in nerve terminals. The increase in the mean amplitude of MEPPs and the decreased mean rise-time of MEPPs in SOD1(G93A) mice point to post-synaptic related changes. …”
Publicado 2013
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86734por Schoenfelder, Sonja M. K., Marincola, Gabriella, Geiger, Tobias, Goerke, Christiane, Wolz, Christiane, Ziebuhr, Wilma“…Our data further suggest that subsequent steps in metICFE-mdh transcription are tightly controlled by the 5′ met leader-associated T-box riboswitch which mediates premature transcription termination when methionine is present. If methionine supply is limited, and hence tRNA(i) (fMet) becomes uncharged, full-length met leader/metICFE-mdh mRNA is transcribed which is rapidly degraded by nucleases involving RNase J2. …”
Publicado 2013
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86735por Mazere, Joachim, Meissner, Wassilios. G., Sibon, Igor, Lamare, Frédéric, Tison, François, Allard, Michèle, Mayo, Willy“…CONCLUSION: Ch5–Ch6 are the most affected cholinergic pathways in MSA at both cell bodies and thalamic cholinergic terminals. These results underscore the relevant role of [(123)I]-IBVM SPECT for improving our understanding of the pathophysiology in MSA.…”
Publicado 2013
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86736por Opoku-Acheampong, Alexander B., Unis, Dave, Henningson, Jamie N., Beck, Amanda P., Lindshield, Brian L.“…METHOD/PRINCIPAL FINDINGS: Six-week-old C57BL/6 TRAMP x FVB male mice were randomized to AIN93G control or pre- and post- finasteride and dutasteride diet (83.3 mg drug/kg diet) groups (n =30–33) that began at 6 and 12 weeks of age, respectively, and were terminated at 20 weeks of age. The pre- and post- finasteride and dutasteride groups were designed to test the preventive and therapeutic efficacy of the drugs, respectively. …”
Publicado 2013
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86737por Yang, Wei, Wu, Jian-min, Bi, An-ding, Ou-yang, Yong-chang, Shen, Hai-hong, Chirn, Gung-wei, Zhou, Jian-hua, Weiss, Emily, Holman, Emily Pauline, Liao, D. Joshua“…In some trimeric ESTs, the downstream partner was fused to the poly-A tail of the upstream partner, which, together with the mtRNA-nRNA fusions, suggests a possible new mechanism for RNA fusion that occurs after both transcription and splicing have been terminated, and possibly outside the nucleus, in contrast to the two current hypothetical mechanisms, trans-splicing and transcriptional-slippage, that occur in the nucleus. …”
Publicado 2013
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86738por Ha, Sangdeuk, Baver, Scott, Huo, Lihong, Gata, Adriana, Hairston, Joyce, Huntoon, Nicholas, Li, Wenjing, Zhang, Thompson, Benecchi, Elizabeth J., Ericsson, Maria, Hentges, Shane T., Bjørbæk, Christian“…We did not find evidence of LepRb localization or STAT3-signaling in axon-fibers or nerve-terminals of POMC and AgRP/NPY/GABA neurons. Three-dimensional serial EM-reconstruction of dendritic segments from POMC and AgRP/NPY/GABA neurons indicates a high density of shaft synapses. …”
Publicado 2013
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86739por Lisowski, Pawel, Juszczak, Grzegorz R, Goscik, Joanna, Stankiewicz, Adrian M, Wieczorek, Marek, Zwierzchowski, Lech, Swiergiel, Artur H“…In HA mice, we observed the upregulation of genes involved in neurotransmitter transport, the termination of GABA and glycine activity (Slc6a11, Slc6a9), glutamate uptake (Slc17a6), and the downregulation of neuropeptide Y (Npy) and corticotropin releasing hormone-binding protein (Crhbp). …”
Publicado 2013
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86740por Fanian, Ferial, Mac-Mary, Sophie, Jeudy, Adeline, Lihoreau, Thomas, Messikh, Rafat, Ortonne, Jean-Paul, Sainthillier, Jean-Marie, Elkhyat, Ahmed, Guichard, Alexandre, Kenari, Kamran Hejazi, Humbert, Philippe“…The volunteers were examined at baseline, after 4 months, and 6 weeks after termination of treatment (month 5.5). The evaluation included skin microrelief by Visioscan® as the main outcome, and the secondary outcomes were results on standard macrophotography, skin tension by Reviscometer®, skin high-frequency ultrasound, and self-assessment. …”
Publicado 2013
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