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  1. 87101
    “…Sudden death events terminated by defibrillator therapy were similar in women (0.9%/year) versus men (1.0%/year; hazard ratio, 0.92; 95% CI, 0.6–1.5; P=0.73). …”
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    Impact of Sex on Clinical Course and Survival in the Contemporary Treatment Era for Hypertrophic Cardiomyopathy
  2. 87102
    por Melnik, Bodo C.
    Publicado 2019
    “…Translational evidence presented in this perspective implies for the first time that termination of milk miRNA transfer is the driver of this metabolic switch. miRNA-148a is a key inhibitor of AMPK and phosphatase and tensin homolog, crucial suppressors of mTORC1. β-Cells of diabetic patients return to the postnatal phenotype with high mTORC1 and low AMPK activity, explained by continuous transfer of bovine milk miRNAs to the human milk consumer. …”
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    Milk exosomal miRNAs: potential drivers of AMPK-to-mTORC1 switching in β-cell de-differentiation of type 2 diabetes mellitus
  3. 87103
    “…This preliminary and opportunistic study investigated leucopoietic changes in rat bone marrow 6 h following traumatic injury and HS. Terminally anesthetized male Porton Wistar rats were allocated randomly to receive a sham operation (cannulation with no injury) or femoral fracture and HS. …”
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    Flow Cytometric Analysis of Hematopoietic Populations in Rat Bone Marrow. Impact of Trauma and Hemorrhagic Shock
  4. 87104
    “…We detected specific autoantibodies to small dorsal root ganglion (DRG) neurons and their nerve terminals in the dorsal horns of NeP patients with allergic disorders. …”
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    Novel Neuropathic Pain Mechanisms Associated With Allergic Inflammation
  5. 87105
    “…Patients were above the age of 70, representative of the general geriatric population, and not terminally ill. RESULTS: In the inpatient arm, the intervention group (n = 100) experienced a decrease in medications prescribed from admission to discharge of 18.5%, compared with a decrease of 1.9% in the control group (n = 100, difference between groups p < 0.0001). …”
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    Teaching physicians the GPGP method promotes deprescribing in both inpatient and outpatient settings
  6. 87106
    “…Some postoperative gastric cancer patients have to terminate systemic intravenous chemotherapy early due to adverse drug reactions. …”
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    The efficacy and feasibility of adopting intravenous chemotherapy and oral S-1 as a sequential therapy for postoperative gastric cancer patients
  7. 87107
    “…Eligibility for loss type included miscarriage or stillbirth (by any definition), termination of pregnancy for nonviable foetal anomaly, and neonatal death up to 28 days after a live birth. …”
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    Men’s grief following pregnancy loss and neonatal loss: a systematic review and emerging theoretical model
  8. 87108
    por Tao-Cheng, Jung-Hwa
    Publicado 2020
    “…How these proteins are transported from soma to synapses, and how they become concentrated at SV clusters at presynaptic terminals were examined by immunogold electron microscopy in dissociated rat hippocampal neurons at 3–6 days in culture, a developmental stage when axonal transport of SV proteins is robust. …”
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    Immunogold labeling of synaptic vesicle proteins in developing hippocampal neurons
  9. 87109
    “…The study duration is 40 weeks, with a 36-week study period and end of study visit occurring at 40 weeks or at early termination/withdrawal from study. The TEALS study has been registered with the Australian and New Zealand Clinical Trials registry (ANZCTR) under the trials registration number ACTRN12618000534280 and has been approved by the Human Research Ethics Committee and Research Governance Office at the lead site (Westmead Hospital) with the ethics number HREC/17/WMEAD/353. …”
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    Phase 2 randomized placebo controlled double blind study to assess the efficacy and safety of tecfidera in patients with amyotrophic lateral sclerosis (TEALS Study): Study protocol clinical trial (SPIRIT Compliant)
  10. 87110
    “…The use of antazoline, a first-generation antihistamine agent used for rapid conversion of recent-onset atrial fibrillation in patients with preserved left ventricular function and for rapid atrial fibrillation termination during accessory pathway ablation denotes that anaphylaxis-induced histamine production could be the cause of atrial fibrillation at least in some instances. …”
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    Anaphylaxis-Induced Atrial Fibrillation and Anesthesia: Pathophysiologic and Therapeutic Considerations
  11. 87111
    “…Drug-induced liver injury (DILI) is one of the major reasons for termination of drug development. Due to the importance of predicting DILI in early phases of drug development, diverse in silico models have been developed to filter out DILI-causing candidates before clinical study. …”
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    Development of Prediction Models for Drug-Induced Cholestasis, Cirrhosis, Hepatitis, and Steatosis Based on Drug and Drug Metabolite Structures
  12. 87112
    “…However, early transplanted engineered lungs terminated in organ failure in a short period. Immature vasculature reconstruction is considered to be the main cause of engineered organ failure. …”
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    Lung Microvascular Niche, Repair, and Engineering
  13. 87113
    por Singh, Prim B., Newman, Andrew G.
    Publicado 2020
    “…This has implications for the mechanism(s) that maintains cellular identity, be it a terminally differentiated fibroblast or a pluripotent embryonic stem cell.…”
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    On the relations of phase separation and Hi-C maps to epigenetics
  14. 87114
    “…OBJECTIVE: To analyse variaitons in the prevalence of congenital anomaly‐related perinatal mortality attributable to termination of pregnancy for foetal anomaly (TOPFA) and prenatal diagnosis of congenital anomaly prevalence. …”
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    Multilevel analyses of related public health indicators: The European Surveillance of Congenital Anomalies (EUROCAT) Public Health Indicators
  15. 87115
    “…This BL is a phenylene ring with three ethylene chains at 1, 3, and 5 positions, of which the other terminals are connected to 2,2′-bipyridine moieties. …”
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    Efficient trinuclear Ru(ii)–Re(i) supramolecular photocatalysts for CO(2) reduction based on a new tris-chelating bridging ligand built around a central aromatic ring
  16. 87116
    “…L1Oc repeats have a common 3′ end that terminates in a poly A addition signal and an A-rich tract, but individual repeats have different 5′ ends, indicating a polar truncation from the 5′ end during their synthesis or propagation. …”
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    The L1 family of long interspersed repetitive DNA in rabbits: Sequence, copy number, conserved open reading frames, and similarity to keratin
  17. 87117
    “…Cell fractionation revealed temporal gene regulation, in which early lytic gene expression was terminated in late protein-expressing cells. Finally, isolation of fluorescence-positive cells from nonresponders increased dynamic ranges of downstream experiments 10-fold. …”
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    Rainbow Kaposi's Sarcoma-Associated Herpesvirus Revealed Heterogenic Replication with Dynamic Gene Expression
  18. 87118
    “…Next, we induced hepatitis in Sprague–Dawley (SD) rats using repeated alcohol (40%) dosing, and carbon tetrachloride (CCl(4)) 24 hours before termination. Both oral doses of BV-7310 (250 and 500 mg/kg body weight) protected the alcohol-induced body weight loss and significantly improved the elevated levels of liver enzymes compared to the vehicle treated group. …”
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    Hepatoprotective Activity of BV-7310, a Proprietary Herbal Formulation of Phyllanthus niruri, Tephrosia purpurea, Boerhavia diffusa, and Andrographis paniculata, in Alcohol-Induced HepG2 Cells and Alcohol plus a Haloalkane, CCl(4), Induced Liver Damage in Rats
  19. 87119
    “…(Arg411_Gly458del), as did a fetus with a cleft lip and partial intestinal malrotation from a terminated pregnancy within the same pedigree. TBC1D32 was expressed in the developing hypothalamus, Rathke’s pouch, and areas of the hindbrain. …”
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    Loss-of-Function Variants in TBC1D32 Underlie Syndromic Hypopituitarism
  20. 87120
    “…Results: Among 24 participants, the most frequently reported TEAE was decreased appetite (8/24; 33%). At week 8/early termination, mean (standard deviation) systolic and diastolic blood pressure and pulse changes from baseline were −1.1 (7.31) and 1.5 (6.93) mmHg and −0.8 (12.75) bpm, respectively. …”
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    Lisdexamfetamine Dimesylate for Preschool Children with Attention-Deficit/Hyperactivity Disorder
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