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87321por Szefler, Stanley J., Roberts, Graham, Rubin, Adalberto S., Zielen, Stefan, Kuna, Piotr, Alpan, Oral, Anzures‐Cabrera, Judith, Chen, Qiang, Holweg, Cécile T. J., Kaminski, Janusz, Putnam, Wendy S., Matthews, John G., Kamath, Nikhil“…However, the study was prematurely terminated (sponsor's decision) potentially limiting interpretation of results. …”
Publicado 2022
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87322“…Three-dimensional echocardiography with spatio-temporal image correlation and high-definition flow imaging technique was performed to obtain the three-dimensional rendered image, which clearly showed the malformation in space. The pregnancy was terminated and the gross findings confirmed the prenatal diagnosis. …”
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87323por Coyle, Chris S., Prescott, Melanie, Handelsman, David J, Walters, Kirsty A., Campbell, Rebecca E.“…Serial tail‐tip blood sampling was used to measure LH dynamics and perfusion‐fixed brains were collected and immunolabelled for vesicular GABA transporter (VGAT) to assess putative GABAergic terminals associated with GFP‐labelled GnRH neurons. …”
Publicado 2022
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87324por Corselli, Mirko, Saksena, Suraj, Nakamoto, Margaret, Lomas, Woodrow E., Taylor, Ian, Chattopadhyay, Pratip K.“…Comprehensive immunophenotypic and transcriptomic analysis at day 0 enabled a refined characterization of T‐cell maturational states and the identification of a donor‐specific subset of terminally differentiated T‐cells that would have been otherwise overlooked using canonical cell classification schema. …”
Publicado 2021
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87325por Ponterio, Giulia, Faustini, Gaia, El Atiallah, Ilham, Sciamanna, Giuseppe, Meringolo, Maria, Tassone, Annalisa, Imbriani, Paola, Cerri, Silvia, Martella, Giuseppina, Bonsi, Paola, Bellucci, Arianna, Pisani, Antonio“…RESULTS: In the Tor1a(+/Δgag) DYT1 mutant mice, we found a significant reduction of α‐Syn levels in whole striata, mainly involving glutamatergic corticostriatal terminals. Strikingly, the striatal levels of the vesicular SNARE VAMP‐2, a direct α‐Syn interactor, and of the transmembrane SNARE synaptosome‐associated protein 23 (SNAP‐23), that promotes glutamate synaptic vesicles release, were markedly decreased in mutant mice. …”
Publicado 2022
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87326por Kimminau, E.A., Karnezos, T.P., Russo, K.N., Baxter, J.A., Berghaus, R.D., Jones, M., Hofacre, C.L.“…On d 42, the trial was terminated, birds were weighed, and performance was calculated. …”
Publicado 2022
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87327por Ohue, Masayuki, Iwasa, Satoru, Mizusawa, Junki, Kanemitsu, Yukihide, Shiozawa, Manabu, Nishizawa, Yusuke, Ueno, Hideki, Katsumata, Kenji, Yasui, Masayoshi, Tsukamoto, Shunsuke, Katayama, Hiroshi, Fukuda, Haruhiko, Shimada, Yasuhiro“…RESULTS: Between May 2015, and May 2019, 48 patients were randomized to the postoperative arm (n = 26) and the perioperative arm (n = 22). The trial was terminated prematurely due to poor accrual. The 3-year OS in the postoperative and perioperative groups were 66.1 and 84.4%, respectively (HR 0.58, 95% CI [0.14–2.45], one-sided P = 0.23). …”
Publicado 2022
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87328por Cai, Meiying, Lin, Min, Guo, Nan, Fu, Meimei, Xu, Liangpu, Lin, Na, Huang, Hailong“…After genetic counseling, the parents of those two fetuses chose to terminate the pregnancy, while the parents of the three unverified fetuses continued the pregnancy, with normal follow-up after birth. …”
Publicado 2022
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87329por Sowińska, Marta, Szeliga, Monika, Morawiak, Maja, Zabłocka, Barbara, Urbanczyk-Lipkowska, Zofia“…Methods: Two groups of amphiphilic peptide dendrimers terminated with N(1)-butyl and N(1)-aminopentane tryptophan were designed. …”
Publicado 2022
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87330por Feng, Vivian, Tumati, Shankar, Wang, Ruoding, Bawa, Kritleen K., Gallagher, Damien, Herrmann, Nathan, Marzolini, Susan, Oh, Paul, Andreazza, Ana, Lanctôt, Krista L.“…Sleep quality was measured by the self-reported Pittsburgh Sleep Quality Index (PSQI) instrument at baseline and termination. Three sleep factors—perceived sleep quality, sleep efficiency, and daily disturbances—were derived from the PSQI. (3) Results: Among CAD patients (n = 113, 85.0% male, age = 63.7 ± 6.4 years, global PSQI = 5.8 ± 4.0), those with poor sleep (PSQI ≥ 5) had higher baseline 8-ISO levels (F(1, 111) = 6.212, p = 0.014, η(p)(2) = 0.053) compared to those with normal sleep. …”
Publicado 2022
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87331“…The discovered yycH and yycI mutations caused early termination of the genes and loss of function of the proteins, and they subsequently downregulated the expression of proteins controlled by the WalKR two-component system, such as Atl and Sle1. …”
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87332por Zhong, Lisha, Wan, Jiangzhong, Wu, Jia, He, Suling, Zhong, Xuefei, Huang, Zhiwei, Li, Zhangyong“…OBJECTIVE: During the transition from normal to seizure and then to termination, electroencephalography (EEG) signals have complex changes in time-frequency-spatial characteristics. …”
Publicado 2022
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87333por Sarkar, Irene, Davies, Richard, Aarebrot, Anders K., Solberg, Silje M., Petrovic, Aleksandra, Joshi, Anagha M., Bergum, Brith, Brun, Johan G., Hammenfors, Daniel, Jonsson, Roland, Appel, Silke“…RESULTS: We found significant differences in the frequencies of memory B cells, CD8+ T central and effector memory cells and terminally differentiated CD4+ T cells among the healthy donors and patient subgroups. …”
Publicado 2022
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87334por Romsuk, Jutapat, Yasumoto, Shuhei, Fukushima, Ery Odette, Miura, Kenji, Muranaka, Toshiya, Seki, Hikaru“…The “Tsukuba system” is one of the most efficient agroinfiltration-based transient protein expression systems using the vector pBYR2HS, which contains geminiviral replication machinery and a double terminator for boosting expression. Additionally, the pBYR2HS vector contains an expression cassette for the gene-silencing suppressor p19 protein from tomato bushy stunt virus, which can also contribute to enhancing the expression of target proteins. …”
Publicado 2022
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87335por Gebremariam, Tesfay Brhane, Demie, Takele Gezahegn, Derseh, Behailu Tariku, Mruts, Kalayu Brhane“…Maternal near-miss (MNM) refers to a woman who nearly died but survived a complication that occurred during pregnancy, childbirth, or within 42 days of termination of pregnancy. Studies in Ethiopia showed an inconsistent proportion of MNM across time and in different setups. …”
Publicado 2022
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87336por Guo, Lin, Zeng, Jinxiu, Liu, Ziyou, Wei, Zijie, Wen, Caiyun, Zhang, Yue, Chen, Xu, Xie, Heping“…If the blood pressure dropped to ≤90/60 mmHg, one recruitment maneuver was terminated in advance. And both groups of patients used the Dräger- or PB840-imported multifunctional ventilator. …”
Publicado 2022
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87337por Hurt, Ryan T., Croghan, Ivana T., Schroeder, Darrell R., Choi, Doo-Sup, Fischer, Karen, Fokken, Shawn, Ebbert, Jon O.“…Eighty-four overweight and obese (body mass index [BMI], 27-40 kg/m(2)) cigarette smokers were randomized before study termination (lorcaserin: n=40; placebo: n=44). The primary outcomes were weight and waist circumference (WC) changes at 12 and 24 weeks in smokers meeting criteria for prolonged smoking abstinence. …”
Publicado 2022
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87338“…Finally, we analyse an active cylindrical dipole in terms of scalar and vector potential and confirm that the electromotive force produced, and hence potential difference across the terminals is a combination of vector and scalar potential difference depending on the aspect ratio (AR) of the dipole. …”
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87339“…ABSTRACT: During the messenger RNA (mRNA) maturation process, RNA polyadenylation is a key step, and is coupled to the termination of transcription. Various cis-acting elements near the cleavage site and their binding factors would affect the process of polyadenylation, and AAUAAA, a highly conserved hexamer, was the most important polyadenylation signal (PAS). …”
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87340“…This nasal route comprises the olfactory or trigeminal nerves originating from the brain and terminating into the nasal cavity at the respiratory epithelium or olfactory neuroepithelium. …”
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