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  1. 87481
    “…Here we describe a tau RT-QuIC assay (K12 RT-QuIC) that, using a C-terminally extended recombinant 3R tau substrate (K12CFh), enables sensitive detection of Pick disease, Alzheimer disease, and chronic traumatic encephalopathy seeds in brain homogenates. …”
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    A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases
  2. 87482
    “…BACKGROUND: Since people with advanced dementia are usually not able to make complex decisions, it is usually the family caregivers, as proxies, who have to decide on treatments and their termination. However, these decisions are difficult for the caregivers to make, as they are often inadequately informed and cannot properly assess the consequences; moreover, they are concerned about harming the sick person. …”
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    Development and testing of an informative guide about palliative care for family caregivers of people with advanced dementia
  3. 87483
    por Cappell, Mitchell S
    Publicado 2020
    “…She called Chief-of-Gastroenterology who advised endoscopists to terminate their esophagogastroduodenoscopies (fulfilling ethical imperative of “physician, first-do-no-harm”), and go to emergency room for medical evaluation. …”
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    Two case reports of novel syndrome of bizarre performance of gastrointestinal endoscopy due to toxic encephalopathy of endoscopists among 181767 endoscopies in a 13-year-university hospital review: Endoscopists, first do no harm!
  4. 87484
    “…The MHV-RI S gene cDNA (from nucleotide 277-termination codon) was inserted in frame into pMIDI, a full-length cDNA clone of an MHV-A59 DI, yielding pDPRIS. …”
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    Recombinant Genomic RNA of Coronavirus MHV-A59 after Coreplication with a DI RNA Containing the MHV-RI Spike Gene()
  5. 87485
    “…The 5′ end of the consensus contains frequent terminators in all three reading frames and has a relatively high GC content with numerous stretches of weak homology with AluI repeats. …”
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    Origin of the human L1 elements: Proposed progenitor genes deduced from a consensus DNA sequence()
  6. 87486
    por Tulchinsky, Theodore H.
    Publicado 2018
    “…Future generations of public health leaders and staff will face many ethical issues such as mandatory immunization of health workers and school children, and assisted death of terminally ill patients.…”
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    Ethical Issues in Public Health
  7. 87487
    por Mengistu, Mekoya D., Kuma, Tilahun
    Publicado 2020
    “…About 46% of mothers required interventions to terminate the pregnancy either by cesarean section (42.3%) or instrumental deliveries (3.7%) due to conditions related to Hypertensive disorders. …”
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    Feto-maternal outcomes of hypertensive disorders of pregnancy in Yekatit-12 Teaching Hospital, Addis Ababa: a retrospective study
  8. 87488
    “…PURPOSE: This study investigated (1) long-term adherence to and persistence with ZA treatment in a real-world setting, (2) extent to which an adverse reaction to ZA impacted on adherence and persistence, and (3) whether there were sex or age differences in patients that had early treatment termination (ETT) due to AEs and those who adhered to the regimen. …”
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    Adherence to and persistence with zoledronic acid treatment for osteoporosis—reasons for early discontinuation
  9. 87489
    “…We also found that hotspot regions contained fewer known retroelement sequences than expected and were overrepresented near transcription start and termination sites. We find mutations in FIGL-1, a protein shown to downregulate cross-over frequency in Arabidopsis, statistically associated to higher recombination rates in domesticated Criollo. …”
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    Genetic differentiation and intrinsic genomic features explain variation in recombination hotspots among cocoa tree populations
  10. 87490
    “…MAIN CONCLUSION: The accumulation of NiCo following the termination of the accumulation of iron in chloroplast suggests that NiCo is not solely involved in iron uptake processes of chloroplasts. …”
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    The developmental and iron nutritional pattern of PIC1 and NiCo does not support their interdependent and exclusive collaboration in chloroplast iron transport in Brassica napus
  11. 87491
    “…The majority of these pregnant women with ectopia vesicae have terminated their pregnancies by cesarean section due to malpresentation, preterm labor or other indications. …”
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    Repeated successful vaginal delivery in a pregnant woman with unrepaired ectopia vesicae and split pelvis: a case study
  12. 87492
    “…CONCLUSIONS: A faster termination of the stress response (higher coping ability) may limit the negative effects of stress on tau deposition. …”
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    Better stress coping associated with lower tau in amyloid-positive cognitively unimpaired older adults
  13. 87493
    “…TF/FVIIa/β1-integrins terminated this inhibition by activation of Src family kinases and subsequent phosphorylation of caveolin-1 on tyrosine 14. …”
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    Activation of β1 integrins and caveolin-1 by TF/FVIIa promotes IGF-1R signaling and cell survival
  14. 87494
    “…Trial registration: NCT01978509 (terminated). Retrospectively registered on November 07, 2013.…”
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    Effect of bowel preparation volume in inpatient colonoscopy. Results of a prospective, randomized, comparative pilot study
  15. 87495
    “…During the treatment period, the animals were observed for mortality, clinical signs (detailed daily and weekly clinical observations), functional observation battery, weekly body weight, and food and water consumption and were also subjected to ophthalmological examination and urinalysis. After termination of the repeated-dose 28-day, 90-day, and recovery studies, clinical pathology (hematology, blood coagulation time, and serum biochemistry), necropsy (organ weights and gross findings), and histopathological examinations were performed. …”
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    Oral toxicity of titanium dioxide P25 at repeated dose 28-day and 90-day in rats
  16. 87496
    “…Coherent mapping was better in identifying CI/breakout sites where ablation terminated the tachycardia (96.2% vs 69.2%; P = .010) and identified significantly more CI (mean/chamber 2.0 ± 1.1 vs 1.0 ± 0.7; P < .001) with narrower width (19.8 ± 10.5 vs 43.0 ± 23.9 mm; P < .001) than conventional mapping. …”
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    Identification of critical isthmus using coherent mapping in patients with scar‐related atrial tachycardia
  17. 87497
    “…Increasing numbers of people with personality disorders, faced with unbearable suffering, have requested and received assistance in terminating their lives. EAS in people with personality disorders has, however, received very sparse attention from clinicians and researchers. …”
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    Euthanasia and assisted suicide in patients with personality disorders: a review of current practice and challenges
  18. 87498
    “…AIMS: Atrial fibrillation (AF) often starts as a paroxysmal self-terminating arrhythmia. Limited information is available on AF patterns and episode duration of paroxysmal AF. …”
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    Temporal patterns and short-term progression of paroxysmal atrial fibrillation: data from RACE V
  19. 87499
    “…We found that upregulation of CDK3 and downregulation of many mitosis regulation factors, like the HAUS genes, might be responsible for bypassing the G1/S checkpoint and termination of mitosis, respectively. We postulate that GCT cells do not tolerate these alterations in the cell cycle and eventually induce apoptosis. …”
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    CDK4/6 inhibition presents as a therapeutic option for paediatric and adult germ cell tumours and induces cell cycle arrest and apoptosis via canonical and non-canonical mechanisms
  20. 87500
    “…Six patients (16.7%) terminated OAT and one patient (2.8%) was lost to follow-up. …”
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    A stepwise titration protocol for oral appliance therapy in positional obstructive sleep apnea patients: proof of concept
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