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87801“…To understand the role of HSP90.5 in chloroplast function and biogenesis, in this study, we generated transgenic Arabidopsis plants that overexpress a C-terminally FLAG-tagged HSP90.5. By characterizing three HSP90.5 cosuppression lines, we demonstrated the essential role of HSP90.5 in plant growth and chloroplast biogenesis. …”
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87802“…GFP expression in calyx of Held terminals was more robust in <P15 compared to >P15 mice. …”
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87803“…About 60% of the calls are terminated on the telephone through provision of medical advice and prescription of medication. …”
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87804por Tatarkiewicz, K, Hargrove, D M, Jodka, C M, Gedulin, B R, Smith, P A, Hoyt, J A, Lwin, A, Collins, L, Mamedova, L, Levy, O E, D’Souza, L, Janssen, S, Srivastava, V, Ghosh, S S, Parkes, D G“…We aimed to investigate the therapeutic potential of the novel N- and C-terminally modified GIP analogue AC163794. METHODS: AC163794 was synthesized by solid-phase peptide synthesis. …”
Publicado 2014
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87805por Liu, Junhua, Liu, Bin, Zhang, XiaoYun, Yu, Baocong, Guan, Wuqiang, Wang, Kun, Yang, Yang, Gong, Yifan, Wu, Xiaojing, Yanagawa, Yuchio, Wu, Shengxi, Zhao, Chunjie“…We found that the calcium-binding protein calretinin (CR) is dynamically expressed in L5a excitatory pyramidal neurons of the barrel cortex, and L5a neurons form a unique serrated pattern similar to the distributions of their presynaptic POm axon terminals. 2. Infraorbital nerve transection disrupts this unique alignment, indicating that it is input dependent. 3. …”
Publicado 2014
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87806por Bebbere, Daniela, Ariu, Federica, Bogliolo, Luisa, Masala, Laura, Murrone, Ombretta, Fattorini, Mauro, Falchi, Laura, Ledda, Sergio“…Conversely, OOEP2 contains a premature termination codon, thus representing an alternative noncoding transcript and supporting the existence of aberrant splicing during ovine oogenesis. …”
Publicado 2014
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87807por Hara, Kiyotaka Y, Morita, Toshihiko, Mochizuki, Masao, Yamamoto, Keisuke, Ogino, Chiaki, Araki, Michihiro, Kondo, Akihiko“…RESULTS: Here, we developed a multiple gene expression system using plasmids containing three strong promoters in X. dendrorhous (actin, alcohol dehydrogenase and triose-phosphate isomerase) and their terminators. Using this system, three mevalonate synthetic pathway genes encoding acetoacetyl-CoA thiolase, HMG-CoA synthase and HMG-CoA reductase were overexpressed at the same time. …”
Publicado 2014
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87808“…KX was not antagonized, but ISO delivery was terminated 40 minutes after induction and MMF was reversed with atipamezole-flumazenil-naloxone (AFN, 0.75 mg·kg(−1) + 0.2 mg·kg(−1) + 0.12 mg·kg(−1), s.c.). …”
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87809“…Nine trials have been completed and 5 have been terminated early or withdrawn. Nine trials have data available when individually searched using MEDLINE and/or Google. …”
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87810por Arkhypchuk, Anna I, Orthaber, Andreas, Mihali, Viorica Alina, Ehlers, Andreas, Lammertsma, Koop, Ott, Sascha“…In contrast, a high-lying transition state TS(E′–F′)(R=Ph) of 37 kcal mol(−1) is found when the substituent is a phenyl group, thus explaining the experimental observation that aryl-terminated diethynylketones 10 and 11 exclusively form bisphospholes 16 and 17.…”
Publicado 2013
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87811por Bone, H. G., Dempster, D. W., Eisman, J. A., Greenspan, S. L., McClung, M. R., Nakamura, T., Papapoulos, S., Shih, W. J., Rybak-Feiglin, A., Santora, A. C., Verbruggen, N., Leung, A. T., Lombardi, A.“…We describe the phase III Long-Term ODN Fracture Trial (LOFT), an event-driven, randomized, blinded placebo-controlled trial, with preplanned interim analyses to permit early termination if significant fracture risk reduction was demonstrated. …”
Publicado 2014
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87812“…RESULTS: This study and protocol was fully funded, but it was terminated prior to review from ethics boards and study implementation. …”
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87813por Koinuma, Toshitaka, Nunomiya, Shin, Wada, Masahiko, Koyama, Kansuke, Suzuki, Takahiro“…A tumor necrosis factor-alpha inhibitor, etanercept, has been reported to be a promising treatment option for post-HSCT patients with IPS; however, the phase III clinical trial of etanercept has recently been terminated without definitive conclusion. If post-HSCT patients with IPS really benefit from etanercept, mechanical ventilation (MV)-dependent IPS patients might be worth receiving ECMO treatment in line with the protective lung strategy. …”
Publicado 2014
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87814por Yi, Feng, Catudio-Garrett, Elizabeth, Gábriel, Robert, Wilhelm, Marta, Erdelyi, Ferenc, Szabo, Gabor, Deisseroth, Karl, Lawrence, Josh“…The HC of ChAT-tauGFP mice was densely innervated with GFP-positive axons, often accompanied by large GFP-positive structures, some of which were Neurotrace/DAPI-negative and likely represent large axon terminals. In the HC of ChAT-Rosa mice, ChAT-YFP cells were Neurotrace-positive and more abundant in CA3 and dentate gyrus than CA1 with partial overlap with calretinin/VIP. …”
Publicado 2015
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87815por Berendsen, Brenda AJ, Kremers, Stef PJ, Savelberg, Hans HCM, Schaper, Nicolaas C, Hendriks, Marike RC“…In addition, sustainability (i.e. continuation of the CLI in practice after study termination) was evaluated. METHODS: Existing frameworks were combined to design the process evaluation for our intervention and setting specifically. …”
Publicado 2015
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87816por Li, Tian-Tian, Wang, Zhao-Jun, Yang, Song-Bai, Zhu, Jun-Hong, Zhang, Shi-Zhong, Cai, San-Jin, Ma, Wen-Han, Zhang, Ding-Qi, Mei, Zhi-Gang“…Assessment is planned at baseline (before treatment) and in the 4th and 8th week, with further follow-up visits after termination of the treatment at the 12th week. Any adverse events will be promptly documented. …”
Publicado 2015
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87817por Bélanger, Emmanuelle, Rodríguez, Charo, Groleau, Danielle, Légaré, France, Macdonald, Mary Ellen, Marchand, Robert“…The tendency to delay conversations about care options represents a barrier that impedes the ability of terminally-ill patients to participate in decision-making. …”
Publicado 2014
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87818“…CONCLUSIONS: The main cause of the differing sensitivity of rods and cones is cones’ ability to terminate their photoresponse faster.…”
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87819por Kakkos, Stavros K., Tsolakis, Ioannis A., Papadoulas, Spyros I., Lampropoulos, George C., Papachristou, Evangelos E., Christeas, Nikolaos C., Goumenos, Dimitrios, Lazarides, Miltos K.“…RESULTS: Transposed brachio-basilic vein fistula maturation rate after primary procedures (3/9, 33%) was lower compared to maturation rate after staged procedures (7/7, 100%, P = 0.011, Fisher’s exact test), which led to premature termination of the trial. Time to hemodialysis [median (interquartile range)] of primary and staged procedures was 54 (51.5–113.5) days and 97 (93–126) days, respectively (P = 0.16). …”
Publicado 2015
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87820por Stiel, Stephanie, Heckel, Maria, Bussmann, Sonja, Weber, Martin, Ostgathe, Christoph“…However, concerns are obvious regarding the ethical implications of involving terminally ill and even dying patients and their informal caregivers as research participants. …”
Publicado 2015
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