“…A model for a short-loop feedback interaction is presented whereby locally released ATP acts upon P2Y receptors in adrenergic cells, inhibiting Ca(2+ )influx and contributing to terminate evoked epinephrine secretion.…”
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“…Furthermore, surface residency, normally of short duration in wild-type cells (terminated by endocytosis to the vacuole), was found to be prolonged; the majority of the receptor protein remained surface localized fully 2 h after biosynthesis. …”
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“…It has been shown that no claim of relief from the carrier condition can be based on three consecutive negative swabs at weekly intervals since apparent spontaneous "cures," as evidenced by negative swabs, may last for 4½ months and finally be terminated by the reappearance of the same strain as that carried before. …”
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“…Small doses of virus provoked a significantly higher proportion of non-fatal infections than large doses; while different 17D substrains, tested over equivalent ranges of virus dose, varied greatly with respect to the proportion of infections which did not terminate with death. In the case of two substrains (17DD low and 17D(3)), non-fatal infections (as demonstrated by resistance to intracerebral challenge with neurotropic virus) were sufficiently frequent to cause an increase, when included in the computation of the infective titers, of 25 per cent above the figures based on deaths alone. …”
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“…The experimental regimens were begun at different times before infection, and were continued until death of the animal, or until termination of the experiment. It was found that mice on the 8 C diet exhibited much greater susceptibility to infection than did mice on the 20 C diet; mice receiving pellets were intermediate between these two groups. …”
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“…The 4-parameter model includes BLC at MSE termination and amplitudes and rate constants of increase (A(1), y(1)) and decrease (A(2), y(2)) of post MSE-BLC. …”
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“…Expression of Ia antigen (Ag) is enhanced up to fourfold, but plasma membrane receptors that mediate binding and uptake of mannosyl/fucosyl-terminated glycoconjugates (MFR), Fc receptors, and the macrophage (mφ)-specific Ag F4/80 are reduced by 50-80 percent. …”
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“…These result in a frame shift that creates a premature termination codon and potential polyadenylation site, respectively. …”
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“…These results suggest that proliferation by terminally differentiated Th1 clones, in contrast to naive T cells, requires stimulation via membrane-bound B7 and a cytokine, IL-12. …”
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“…Activation becomes manifest some time after termination of the activating pulse. 6. With currents of slowly increasing strength it is possible to reach current strengths several times higher than rheobase without obtaining activation (accomodation). …”
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“…The duration of InsP(3)-evoked flux, measured as 10–90% risetime, showed a good reciprocal correlation with d[Ca(2+)](i)/dt and much less cell to cell variation than the dependence of flux on InsP(3) concentration, suggesting that the rate of termination of the Ca(2+) flux depends on the free Ca(2+) flux itself. …”
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“…In adult human skin the basal cell membrane facing the dermal membrane is continuous with, or adjacent to regularly spaced groups of small dense rodlets at which tonofilaments are attached and appear to terminate. Less dense spherical granules are also found in the cellular ectoplasm and are unattached to filaments. 4. …”
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“…There are two possible ways the c.78+1G>C splice site mutation may lead to frameshift and introduce a premature termination codon at the beginning of exon 3: after activation of the next cryptic splice site by a 10 bp insertion or after exon skipping by a 26 bp deletion. …”
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“…Also, these results emphasize the importance of explicitly accounting for entry into desensitization as one of the pathways for burst termination, if meaningful mechanistic insight is to be inferred from the study of the effect of these naturally occurring mutations on channel function. …”
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“…RESULTS: This study was terminated early following a planned interim analysis at 26 weeks. …”
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“…RESULTS: Mice treated with 2ME2 beginning 24 hours post anti-collagen monoclonal antibody injection, showed a dose-dependent inhibition in mean arthritic scores. At study termination (day 21), blinded histomorphometric assessments of sectioned hind limbs demonstrated decreases in synovial inflammation, articular cartilage degradation, pannus formation, osteoclast activity and bone resorption. …”
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“…However, it is not known if the vector would affect the expression of cloned genes via nonsense-mediated mRNA decay (NMD), an mRNA surveillance system that degrades mRNA with a premature termination codon (PTC). In mammalian cells, the induction of NMD requires either a long 3'UTR or the presence of an exon-junction complex downstream of a PTC. …”
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“…Our sRNAscanner tool uses position weight matrices derived from experimentally defined E. coli K-12 MG1655 sRNA promoter and rho-independent terminator signals to identify intergenic sRNA TUs through sliding window based genome scans. …”
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“…RESULTS: The phylogenetic position of the acariform mites is examined through employing SSU, partial LSU sequences, and morphology from 91 chelicerate extant terminals (forty Acariformes). In a static homology framework, molecular sequences were aligned using their secondary structure as guide, whereby regions of ambiguous alignment were discarded, and pre-aligned sequences analyzed under parsimony and different mixed models in a Bayesian inference. …”
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“…(Asterales: Asteraceae), Brazilian pepper tree, Schinus terebinthifolius Raddi (Sapindales: Anacardiaceae), ti plant, Cordyline terminate (L.) Chev.(Liliales: Liliaceae), guava and several Citrus spp. were identified as preferred roosting hosts for oriental fruit fly. …”
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