“…In contrast the prevalence of lesions grouped together as left ventricular outflow tract obstruction (which includes hypoplastic left heart syndrome) decreased from 0.689/1000 (95% CI 0.607–0.776) in 1995–99, to 0.475/1000 (95% CI 0.392–0.565; P = 0.004) in 2010–17, which would be consistent with improved prenatal detection and consequent termination of pregnancy when these very severe lesions are discovered. …”
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“…Then, coupled with the simulated unlabeled samples generated by the trained DCGAN, we conducted iterative semisupervised learning, which continually improved the classification performance of the fuzzy Co-forest until the termination condition was reached. Finally, we tested the fuzzy Co-forest and compared its performance with that of a C4.5 random decision forest and the G2C-CAD system without the fuzzy scheme, using ROC and confusion matrix for evaluation. …”
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“…The treatment was continued for 12 cycles unless the patient had progressive disease (PD), stable disease (SD) with symptom deterioration, unacceptable adverse events, or requested to terminate the treatment prematurely. The primary endpoint was objective response rate (ORR). …”
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“…Approximately half of the trials (311 [51.8%]) assessed at least 1 clinical outcome. Of 300 terminated or completed trials, 204 trials (68.0%) had reported results on ClinicalTrials.gov a median (interquartile range) 16 (13-25) months after their primary completion date. …”
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“…In addition, ICP0’s facilitation activity may lie in its carboxyl-terminated domain. Thus, our results demonstrate that α0’s mRNA and protein possess proapoptotic properties. …”
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“…BACKGROUND: There is substantial evidence that patients with ankylosing spondylitis (AS) have high response rates to tumour necrosis factor inhibitors (TNFi), a low likelihood of successful treatment termination, but yet a limited drug retention. Whereas several reports have assessed drug retention rates for TNFi in AS, there are few, if any, studies investigating the actual treatment trajectories on a patient level, including subsequent therapy changes and dose reductions, of individual patients. …”
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“…Convulsive status epilepticus was terminated in 106 (70%) children in the levetiracetam group and in 86 (64%) in the phenytoin group. …”
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“…The KNDy hypothesis for GnRH/LH pulse generation posits that each pulse of GnRH is caused by a pulse of kisspeptin secretion and that each pulse of kisspeptin is turned on (stimulated) by neurokinin B (NKB; encoded by Tac2) and terminated (inhibited) by dynorphin (encoded by pDyn). …”
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“…Male and female mice of two strains received infusions of 200nL of 100ng/uL, 200ng/uL and 400ng/uL concentrations of kiss-sap and blank-sap into the preoptic area, which contains the greatest density of GnRH neuron cell bodies, and, at the level of the GnRH neuron dendron prior to termination in the median eminence. Mice were perfused two or three weeks after infusion. …”
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“…Four of these 7 couples had successful pregnancies each resulting in live births (all singletons), 1 couple was unable to achieve pregnancy, 1 chose to terminate the pregnancy as the karyotype detected a Turner fetus (45XO) and outcome data was not reported in one. …”
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“…A second fecal sample was collected two weeks post operation. At termination, blood samples were collected and fat pads were removed and weighed. …”
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“…First-trimester placentas were collected from miscarriages and elective termination of pregnancies, tissue microarrays were constructed, and then the expression of Gal-13 and Gal-14 was analyzed by immunohistochemistry and immunoscoring. …”
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“…We confirmed the mitochondrial localization of GFP-PiDHODH showing colocalization with mCherry-labeled ATPase in a transgenic pathogen. N-terminally truncated versions of the two DHODHs were overproduced in E. coli, purified, and kinetically characterized. …”
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“…It was recorded 2 d after termination of the DSS-treatment, followed by a progressive return to values similar to those of control mice. …”
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“…Moreover, the absolute number of Tcyt and terminally differentiated CD45RA-positive effector T-cells (TEMRA) subset was significantly higher in SAS vs. …”
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“…RESULTS: The CAPPA framework specifies 38 elements of a comprehensive analysis of PA policies in the following six categories, which comprise the building blocks of the framework: (i) purpose of analysis (including auditing and assessment of policies); (ii) policy level (including: international; national; subnational; local; and institutional policies); (iii) policy sector (including: health; sport; recreation and leisure; education; transport; environment; urban/rural planning and design; tourism; work and employment; public finance; and research sectors); (iv) type of policy (including: formal written policies; unwritten formal statements; written standards and guidelines; formal procedures; and informal policies); (v) stage of policy cycle (including: agenda setting; formulation; endorsement/legitimisation; implementation; evaluation; maintenance; termination; and succession); and (vi) scope of analysis (including availability; context; processes; actors; political will; content; and effects). …”
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“…Resident denial and efforts to hide smoking were shared as challenges to enforcement, along with a perception that concrete evidence would be needed in eviction court and that simply the smell of SHS was insufficient evidence of violation. Over half had terminated leases or evicted residents due to violations of the smoke-free policy. …”
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“…MAIN OUTCOMES AND MEASURES: Severe maternal morbidity and maternal death during pregnancy and within 6 weeks after termination of pregnancy. RESULTS: During the study period, there were 3 162 303 new pregnancies (mean [SD] maternal age, 29.5 [5.6] years) and 3 533 259 related hospital admissions. …”
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“…Peptidoglycan is typically composed of a glycan backbone of alternating N-acetylglucosamine (GlcNAc) and MurNAc residues that terminates with anhydroMurNAc (anhMurNAc), and short peptides via which the sugar backbones are cross-linked to build up a bag-shaped network. …”
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“…These results point toward a novel mechanism by which chronic developmental TCE exposure may alter terminally differentiated CD4(+) T cell function in adulthood.…”
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