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88641por Bahadur, Gulam, Homburg, Roy, Bosmans, Judith E, Huirne, Judith A F, Hinstridge, Peter, Jayaprakasan, Kanna, Racich, Paul, Alam, Rakib, Karapanos, Ioannis, Illahibuccus, Afeeza, Al-Habib, Ansam, Jauniaux, Eric“…Reliable levels of IVF-related MGP, OHSS (ovarian hyperstimulation syndrome), fetal reductions and terminations are revealed. CONCLUSION: IUI success rates are much closer to IVF than previously reported, more cost-effective in delivering 1 LB, and associated with lower risk of complications for maternal and neonatal complications. …”
Publicado 2020
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88642por Parets, Sebastià, Irigoyen, Ángel, Ordinas, Margarita, Cabot, Joan, Miralles, Marc, Arbona, Laura, Péter, Mária, Balogh, Gábor, Fernández-García, Paula, Busquets, Xavier, Lladó, Victoria, Escribá, Pablo V., Torres, Manuel“…Many drugs and therapies have been designed and developed in the past decade to stop or slow down this neurodegenerative process, although none has successfully terminated a phase-III clinical trial in humans. Most therapies have been inspired by the amyloid cascade hypothesis, which has more recently come under question due to the almost complete failure of clinical trials of anti-amyloid/tau therapies to date. …”
Publicado 2020
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88643por Raihan, Said Majdood, Moniruzzaman, Mohammad, Park, Youngjin, Lee, Seunghan, Bai, Sungchul C.“…The experimental diets were manufactured to contain 0 (Control), 10 (I-Hg10, O-Hg10), 20 (I-Hg20, O-Hg20), 40 (I-Hg40, O-Hg40) and 160 (I-Hg160, O-Hg160) mg/kg diet in organic form as methylmercury (MeHg) or in inorganic form as mercuric chloride (HgCl(2)). At the termination of the experimental trial, weight gains (WGs) of fish fed the control and 10 (I-Hg10, O-Hg10) diets were remarkably higher than those of fish fed the 20 (I-Hg20, O-Hg20), 40 (I-Hg40, O-Hg40) and 160 (I-Hg160, O-Hg160) (p < 0.05). …”
Publicado 2020
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88644“…Serum free fatty acid (FFA), triglyceride (TG), and hepatic TG were measured at study termination. We compared histology and the mRNA/protein markers of hepatic and adipose tissue lipid metabolism between the two groups of mice. …”
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88645por Jan, Asad, Richner, Mette, Vægter, Christian B, Nyengaard, Jens R, Jensen, Poul H“…Harnessing the capability of some recombinant adeno-associated virus serotypes for retrograde transduction may potentially address such limitations (Note: The term retrograde transduction in this manuscript refers to the uptake of injected recombinant adeno-associated virus particles at nerve terminals, retrograde transport, and subsequent transduction of nerve cell soma). …”
Publicado 2019
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88646por Behrens, Martin, Zschorlich, Volker, Mittlmeier, Thomas, Bruhn, Sven, Husmann, Florian“…Neuromuscular function was assessed before and after exercise termination during each condition (IPC, IPC(tm), and SHAM) to analyze the impact of IPC on performance fatigability and its central and peripheral determinants. …”
Publicado 2020
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88647por Harmon, Deidre D, Hancock, Dennis W, Stewart, Robert L, Lacey, Jenna L, Mckee, Robert W, Hale, John D, Thomas, Chevise L, Ford, Elyse, Segers, Jacob R, Teutsch, Chris D, Stelzleni, Alexander M“…Hand grab samples for forage nutritive value determination and quadrat clippings for species compositions were measured on d 0 and on 34-d intervals until termination of the trial. Forage mass was lowest (P < 0.01) for PMCG at the initiation of the grazing trial, whereas BMR was greater (P < 0.01) than SS at wk 6. …”
Publicado 2019
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88648“…Given renal failure, a CT non-contrast of the adrenal glands was performed with normal findings. She elected to terminate the high-risk pregnancy. Based upon her young age at presentation, family history of early onset hypertension, grossly elevated aldosterone: renin ratio and unrevealing workup for a primary tumor or hyperplastic adrenals, a diagnosis of familial hyperaldosteronism was considered. …”
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88649por Baldi, Giulia, Yen, Con-Ning, Daughtry, Morgan R., Bodmer, Jocelyn, Bowker, Brian C., Zhuang, Hong, Petracci, Massimiliano, Gerrard, David E.“…The elevated ultimate pH (pH(u)) found in wooden breast (WB) meat suggests an altered muscular energetic status in WB but also could be related to a prematurely terminated post-mortem pH decline. The aims of this study were to explore the factors contributing to the elevated pH(u) and establish whether the occurrence of WB defect alters muscle post-mortem carbohydrate metabolism and determine if the contractile apparatus reflects such changes. …”
Publicado 2020
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88650por Nangaku, Masaomi, Kanda, Hironori, Takama, Hirotaka, Ichikawa, Tomohiro, Hase, Hiroki, Akizawa, Tadao“…However, the phase 3 study, Bardoxolone Methyl Evaluation in Patients with Chronic Kidney Disease and Type 2 Diabetes Mellitus: the Occurrence of Renal Events (BEACON), was terminated prematurely because bardoxolone methyl increased the risk for early-onset fluid overload in patients with identifiable risk factors for heart failure (elevated baseline B-type natriuretic peptide levels >200 pg/ml and prior history of hospitalization for heart failure). …”
Publicado 2020
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88651por Ambarsari, Cahyani Gita, Hidayati, Eka Laksmi, Hasan, Irsan, Grace, Angela, Oswari, Hanifah“…HCV infection did not resolve, in addition, she experienced thrombocytopenia—which is a side effect of interferon—resulting in termination of interferon treatment. Both cases were treated with DAAs one year following renal transplantation after reaching stable graft function, leading to achievement of sustained virological response at 24 weeks. …”
Publicado 2020
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88652Publicado 2019“…METHODS: Adult ITP patients who were refractory to first-line glucocorticoid therapy and underwent selective surgery were enrolled to be treated with rhTPO at the dosage of 1.5×10(4)U/d subcutaneously during the perioperative period. rhTPO treatment would not be terminated until one of the following conditions occurred: ①Platelet counts met the requirement of surgery; ②Platelet counts were ≥100×10(9)/L; ③Completed the 14 days of therapy. …”
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88653por Veenstra, Jan A.“…In several non-Dipteran insects these peptides have C-terminally extensions that are alternatively spliced. …”
Publicado 2020
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88654Publicado 2017“…RESULTS: ①Among the 410 patients, 8 cases (1.95%) were contrary to the selected criteria, 35 cases (8.54%) lost, 19 cases (4.63%) experienced adverse events, 12 cases (2.93%) were eligible for the termination criteria, 15 cases (3.66%) develpoed disease progression or recurrence, thus the rest 321 cases (78.29%) were into the Per Protocol Set. ②During the first to fourth treatment cycles, the incidences of grade Ⅳ neutropenia after prophylactic use of PEG-rhG-CSF were 19.14% (49/256), 12.5% (32/256), 12.18% (24/197), 13.61% (20/147), respectively. …”
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88655“…There were two randomized control trials, both of which were for COVID-19 and were terminated early. Most COVID-19 reports described a potential benefit of convalescent plasma on clinical outcomes in severe or critically ill patients with few immediate adverse events. …”
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88656por Rosen, Brandon C., Pedreño-Lopez, Nuria, Ricciardi, Michael J., Reed, Jason S., Sacha, Jonah B., Rakasz, Eva G., Watkins, David I.“…Additionally, compared to SIVmac239-specific CTLs, greater proportions of RhCMV-specific CTLs were of the terminally differentiated effector memory phenotype (CD28(–) CCR7(–)) during chronic SIVmac239 infection. …”
Publicado 2020
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88657por Chen, Qiuqiang, Jia, Gang, Zhao, Xiaolei, Bao, Ying, Zhang, Yu, Ozkan, Cengiz, Minev, Boris, Ma, Wenxue“…Survivin (SV) is highly expressed predominantly in most cancer cells and tissues but is absent or undetectable in terminally differentiated normal adult tissues. Therefore, it functions as an almost universal tumor antigen. …”
Publicado 2020
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88658por Thu, Ha T., Lien, Nguyen T.K., Lanh, Pham T., Duong, Bui T.T., Hoa, Nguyen T., Phuoc, Man H., Thai, Pham H., Quyen, Dong Van“…RESULTS: The two Vietnamese DWV strains comprised 10,113 bp and contained a large single open reading frame (ORF) of 2,893 amino acids, initiating at nucleotide 1,130 and terminating at nucleotide 9,812. Multiple nucleotide sequence alignment between these two DWV-VN strains and DWV strains in A. mellifera was performed. …”
Publicado 2020
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88659por Etafa, Werku, Wakuma, Bizuneh, Fetensa, Getahun, Tsegaye, Reta, Abdisa, Eba, Oluma, Adugna, Tolossa, Tadesse, Mulisa, Diriba, Takele, Tagay“…Similarly, nurses who had no PC service experience [AOR = 0.41, CI (0.21–0.79), p = 0.008], who read articles/brochures about PC [AOR = 1.94, CI (1.11–3.39), p = 0.01] and had provided care for a smaller number of terminally ill patients [AOR = 1.74, CI (1.01–2.97), p = 0.04] were significantly associated with nurses’ attitude towards end-of-life care. …”
Publicado 2020
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88660por Jędrzak, Artur, Grześkowiak, Bartosz F, Golba, Klaudia, Coy, Emerson, Synoradzki, Karol, Jurga, Stefan, Jesionowski, Teofil, Mrówczyński, Radosław“…CONCLUSION: Here, we present two types of nanomaterials (nanoparticles and spheres) based on polydopamine and PAMAM dendrimers g.5.0 functionalized with NHS-PEG-Mal linker terminated with folic acid for in vitro hepatocellular carcinoma treatment. …”
Publicado 2020
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