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88821por Ahmed, Shenaz, Brewer, Alina, Tsigas, Eleni Z., Rogers, Caryn, Chappell, Lucy, Hewison, Jenny“…RESULTS: Women generally favored predictive and diagnostic testing, although not because they would opt for termination of pregnancy. Participants generally disagreed that taking daily low-dose aspirin (LDA) would make them nervous, with disagreement significantly higher in the preterm delivery subgroup. …”
Publicado 2021
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88822por Li, Xinyan, Chen, Wenting, Huang, Xian, Jing, Wei, Zhang, Tongmei, Yu, Quntao, Yu, Hongyan, Li, Hao, Tian, Qing, Ding, Yumei, Lu, Youming“…Pathway specific inhibition by either genetic silencing presynaptic terminals or antagonizing postsynaptic receptors impairs delay of gratification, resulting in the impulsive behaviors. …”
Publicado 2021
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88823por Weichseldorfer, Matthew, Affram, Yvonne, Heredia, Alonso, Rikhtegaran-Tehrani, Zahra, Sajadi, Mohammad M., Williams, Sumiko P., Tagaya, Yutaka, Benedetti, Francesca, Ramadhani, Habib O., Denaro, Frank, Munawwar, Arshi, Bryant, Joseph, Zella, Davide, Reitz, Marvin, Romerio, Fabio, Latinovic, Olga S.“…Major challenges remain, including viral resistance upon termination of cART and persistence and identification of tissue distribution of HIV-1 reservoirs. …”
Publicado 2021
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88824por Maspero, Jorge, Agache, Ioana Octavia, Kamei, Tadashi, Yoshida, Makoto, Boone, Bryan, Felser, James M., Kawakami, Fernando, Knorr, Barbara, Lawrence, David, Lehmann, Thomas, Wang, Wei, Pedinoff, Andrew J.“…In exploratory analyses, reduced rates of moderate-to-severe asthma exacerbations, increased time-to-first moderate-to-severe asthma exacerbation and improved FEV(1) were observed for both doses of fevipiprant versus placebo; these were without multiplicity adjustment and should be interpreted with caution. SPIRIT was terminated early, on 16 December 2019, by the Sponsor. …”
Publicado 2021
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88825por Cheng, Jiaojiao, Ruan, Xiangyan, Du, Juan, Jin, Fengyu, Li, Yanglu, Liu, Xiaowei, Wang, Husheng, Gu, Muqing, Mueck, Alfred O.“…Oncologists recommended termination of the pregnancy. Caesarean section was performed at week 32, and ovarian tissue samples were collected for OTC to preserve fertility and ovarian endocrine function. …”
Publicado 2021
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88826“…RESULTS: The sample comprised 21 interviewees from the United Kingdom (UK), having a range of spontaneous pregnancy outcomes, including single and multiple livebirths, miscarriage, ectopic pregnancy and termination of pregnancy. Contraceptive choices were subject to a complex and dynamic interaction of influencing factors including beliefs regarding subfertility, desire for children and views on contraception. …”
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88827por Santos, Andres, Sauer, Madeline, Neil, Alexander J., Solomon, Isaac H., Hornick, Jason L., Roberts, Drucilla J., Quade, Bradley J., Parra-Herran, Carlos“…Eighty one percent of patients in the study group underwent third-trimester delivery; remaining had a first-trimester spontaneous abortion or elective second-trimester termination. Patients received two (52%) or one (48%) vaccine doses during pregnancy, with a median interval between latest dose and delivery of 13 days (range 2–79 days). …”
Publicado 2022
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88828por Chung, Chen-Shuan, Chen, Chieh-Chang, Chen, Kuan-Chih, Fang, Yu-Jen, Hsu, Wen-Feng, Chen, Yen-Nien, Tseng, Wei-Chuang, Lin, Cheng-Kuan, Lee, Tzong-Hsi, Wang, Hsiu-Po, Wu, Yen-Wen“…The data regarding efficacy and safety of EE were analyzed. It was early terminated because the UGIB rate was lower than expected and interim analysis was done. …”
Publicado 2022
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88829“…All questionnaires will be completed by both groups immediately and 8 weeks after the termination of the treatment. The data will be analyzed using linear mixed-effects modeling with random intercepts and slopes. …”
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88830por Moors, Tim E., Mona, Daniel, Luehe, Stefan, Duran-Pacheco, Gonzalo, Spycher, Liz, Mundigl, Olaf, Kaluza, Klaus, Huber, Sylwia, Hug, Melanie N., Kremer, Thomas, Ritter, Mirko, Dziadek, Sebastian, Dernick, Gregor, van de Berg, Wilma D. J., Britschgi, Markus“…Based on immunostainings and biochemical analyses, certain post-translationally modified alpha-synuclein (aSyn) variants, including C-terminally truncated (CTT) and Serine-129 phosphorylated (pSer129) aSyn, are proposed to be involved in the pathogenesis of synucleinopathies such as Parkinson’s disease with (PDD) and without dementia (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). …”
Publicado 2022
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88831por Ni, You, Feng, Yifan, Shen, Dingding, Chen, Ming, Zhu, Xiaona, Zhou, Qinming, Gao, Yining, Liu, Jun, Zhang, Qi, Shen, Yuntian, Peng, Lisheng, Zeng, Zike, Yin, Dou, Hu, Ji, Chen, Sheng“…A wide range of behaviors, including tests of locomotion, coordination, memory, anxiety, depression and social interactions were established. At termination, brain tissue was analyzed for human IgG, neuronal markers, glial markers, synaptic markers and RNA sequencing. …”
Publicado 2022
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88832“…Ethical sensitivity seems to be key and it becomes even more relevant in critical clinical areas, such as the therapeutic pathways of terminally ill patients. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12910-022-00803-x.…”
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88833por Fakhraei, Romina, Erwin, Erica, Alibhai, Kameela M., Murphy, Malia S.Q., Dingwall-Harvey, Alysha L.J., White, Ruth Rennicks, Dimanlig-Cruz, Sheryll, LaRose, Rosemary, Grattan, Kimberly, Jia, Jian-Jun, Liu, George, Arnold, Corey, Galipeau, Yannick, Shir-Mohammadi, Khatereh, Alton, Gillian D., Dy, Jessica, Walker, Mark C., Fell, Deshayne B., Langlois, Marc-André, El-Chaâr, Darine“…We excluded individuals younger than 18 years, those who did not speak English or French, those who enrolled in conflicting studies, those admitted for pregnancy termination and those triaged between 11:31 pm and 7:29 am. …”
Publicado 2022
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88834“…Implantable cardioverter defibrillators (ICD) are an important therapeutic strategy for detecting and terminating ventricular arrhythmias in patients at risk of SCD. …”
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88835por Tatum, James L., Kalen, Joseph D., Jacobs, Paula M., Riffle, Lisa A., James, Amy, Thang, Lai, Sanders, Chelsea, Hollingshead, Melinda G., Basuli, Falguni, Shi, Jianfeng, Doroshow, James H.“…Following the second cycle of therapy, the mice were maintained until their tumors reached a size requiring humane termination. RESULTS: [(18)F]FLT uptake decreased significantly in the palbociclib and combination arms (p = 0.0423 and 0.0106 respectively at day 3 and 0.0012 and 0.0031 at day 9) with stable tumor volume. …”
Publicado 2022
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88836por Marinescu, Ioana M., Rogg, Manuel, Spohn, Simon, von Büren, Moritz, Kamps, Marius, Jilg, Cordula A., Fountzila, Elena, Papadopoulou, Kyriaki, Ceci, Lara, Bettermann, Alisa, Ruf, Juri, Benndorf, Matthias, Adebahr, Sonja, Zips, Daniel, Grosu, Anca L., Schell, Christoph, Zamboglou, Constantinos“…One patient in the radio sensitive group displayed a previously not reported loss of function frameshift mutation in the NBN gene (c.654_658delAAAAC) that introduces a premature termination codon and results in a truncated protein. …”
Publicado 2022
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88837por Alabiad, Mohamed Ali, Said, Warda M. M., Gad, Abdalla Hassan, Sharaf ElDin, Mustafa Taha Abdelfattah, Khairy, Dina Ahmed, Gobran, Mai Ahmed, Shalaby, Amany Mohamed, Samy, Walaa, Abdelsameea, Ahmed Ahmed, Heraiz, Ahmed Ismail“…We aimed at evaluating the effects of different doses of letrozole for termination of ectopic pregnancy and study their effects on villous trophoblastic tissue. …”
Publicado 2022
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88838por Wislez, Marie, Mazieres, Julien, Lavole, Armelle, Zalcman, Gérard, Carre, Olivier, Egenod, Thomas, Caliandro, Raffaele, Dubos-Arvis, Catherine, Jeannin, Gaelle, Molinier, Olivier, Massiani, Marie-Ange, Langlais, Alexandra, Morin, Franck, Le Pimpec Barthes, Francoise, Brouchet, Laurent, Assouad, Jalal, Milleron, Bernard, Damotte, Diane, Antoine, Martine, Westeel, Virginie“…The unexpected 90-day postoperative mortality of four patients led to premature study termination. None of these four deaths was considered secondary to direct durvalumab-related toxicity. …”
Publicado 2022
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88839por Alawode, Oluwatobi Abel, Okeke, Sylvester Reuben, Sah, Rajeeb Kumar, Bolarinwa, Obasanjo Afolabi“…The study found that modern contraceptives use intention among grand-multiparous women in these high fertility countries was predicted by a history of contraceptive use and pregnancy termination, exposure to family planning messages on social media, and knowledge of family planning methods. …”
Publicado 2022
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88840por Adam, Julia, Goletz, Hildegard, Dengs, Stefanie, Klingenberger, Nora, Könnecke, Sonja, Vonderbank, Christina, Hautmann, Christopher, Hellmich, Martin, Plück, Julia, Döpfner, Manfred“…CONCLUSIONS: These results suggest that improvement after an initial 12-week course of treatment may not allow for the prediction of non-responders/non-remitters and for the termination of treatment. Overall, the findings show that results from randomized controlled trials are transferrable to routine care. …”
Publicado 2022
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