“…In contrast to the Hu-HSC model, transformed human B cells are rarely recovered from Hu-PBL mice, in which human B cells terminally differentiate and lose expression of EBV receptor CD21, thus precluding their transformation and recovery. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: This study was terminated early because of the results from a Japanese phase III trial (DELTA trial). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…These included studies in which drug development was terminated. Participants 11 028 participants who received the study drug in 394 distinct non-oncology phase I studies, which involved 4620 unique individuals. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Incompatible interaction with TcLr9 activates defense responses including oxidative burst and micronecrotic reactions associated with the pathogen’s infection structures and leads to complete termination of pathogen development. These two contrasting host-pathogen interactions were a foundation for transcriptome analysis of incompatible wheat-Pt interaction. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The difference in the number of women reporting the combined adverse outcome of miscarriage, termination of pregnancy, stillbirth, or neonatal death in the metformin group (n=7) versus the placebo group (n=2) was not significant (odds ratio 3·60, 95% CI 0·74–17·50; p=0·11). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Immediately following injury, pigs were randomized into (1) LVt (n = 3), positive end-expiratory pressure (PEEP) 5 cmH(2)O, V(t) 6 cc kg(−1), F(i)O(2) 21 %, and guided by the ARDSnet protocol or (2) APRV (n = 3), P(High) 16–22 cmH(2)O, P(Low) 0 cmH(2)O, T(High) 4.5 s, T(Low) set to terminate the peak expiratory flow at 75 %, and F(i)O(2) 21 %. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: From October 2009 to August 2014, 129 children were randomly assigned to DSI + PS (n = 66) or PS (n = 63). The study was terminated prematurely due to slow recruitment rates. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Seven patients (15.9 %) had early termination due to AEs, including weight gain (2), hypertension (2), edema (1), fatigue (1), seizures (1) and for reasons not stated (2). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Thus, given at amnestic minor cognitive impairment (aMCI) or initial symptomatic stages, calcilytics could prevent or terminate the propagation of LOAD neuropathology and preserve human neurons' viability and hence patients' cognitive abilities.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…As a result, Studies 3002 and 3003 were also terminated. In total, 492 and 202 patients were enrolled in Studies 3003 and 3002, respectively. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Grade 3/4 toxicities (worst grade all cycles) included 7 patients (35 %) with neutropenia, 4 patients (20 %) with anaemia, 2 patients (10 %) with thrombocytopenia, and 3 patients (15 %) with fatigue. This study was terminated at the end of Stage I due to a lack of the required (3/18) responders. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Termination of fixed orthodontic treatment is associated with bracket debonding and residual adhesive removal. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Research into the impact of unintended pregnancy on the wellbeing of women tends to focus on pregnancies ending in either termination or lone motherhood. Unintended pregnancy is common in partnered women, but little is known about the association between unintended pregnancy and postpartum affective disorders, such as depression and anxiety in this group. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Existing approaches tend to terminate after outputting the potential discrete binding sites on the sequences, but how to assemble them into the meaningful binding motifs is a topic worth of further investigation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Cerro isolates had an additional cytosine inserted in a cytosine-rich region of the virulence gene sopA, resulting in premature termination of translation likely responsible for loss of pathogenic capacity in humans. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This sequence contains the methylated and universally conserved GGQ motif common for all class-1 translation termination factors responsible for stop codon recognition and for triggering the hydrolysis of the P site-bound peptidyl-tRNA. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In Pathway Commons analysis, the 38 genes were strongly involved in the p63 transcription factor network, while the 41 genes were involved in the RNA polymerase III transcription termination pathway. Several genes such as Nuclear factor I X (NFIX) and TNF receptor association factor 4 (TRAF4) were selected as candidate genes for HIV latency. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: Our data extend endocrine concepts of regulation of GB filling beyond FXR-FGF15/19 and the direct effects of BA via Tgr5, to encompass a novel BA-Tgr5-L cell GLP-2 axis providing nutrient-mediated feedback from BA to terminate meal-related GB contraction. These findings have implications for conditions characterized by elevated circulating levels of GLP-2 such as after bariatric surgery and the development and use of agents that promote Tgr5 activation, L cell secretion, or GLP-2R agonism for the treatment of metabolic disease.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The mean PI-RRT duration was 543.1 ± 119.0 min in the completed sessions and 387.3 ± 140.8 min in the prematurely terminated sessions, without significant difference between AN69ST and AN69 hemofilters. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The settings for APRV were: high airway pressure (P(high)) set at the last plateau airway pressure (P(plat)), not to exceed 30 cmH(2)O) and low airway pressure ( P(low)) set at 5 cmH(2)O; the release phase (T(low)) setting adjusted to terminate the peak expiratory flow rate to ≥ 50%; release frequency of 10–14 cycles/min. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso