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  1. 89141
    “…METHODS: In this prospective cohort study, we analyzed 145,481 men and 147,733 women aged 38–73 years old from UK Biobank (UKB) to investigate the sex-specific associations of total testosterone (TT), free testosterone (FT), or polygenic risk score (PRS) with health span termination (HST) risk. At baseline, serum testosterone levels were measured. …”
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    Sex-Specific Associations of Testosterone and Genetic Factors With Health Span
  2. 89142
    “…In physical health clinics, not adhering to prescribed therapy can take the form of not attending a scheduled clinic visit (no-show appointment) or prematurely terminating treatment against the advice of the provider (self-discharge). …”
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    Effect of a Mobile Health App on Adherence to Physical Health Treatment: Retrospective Analysis
  3. 89143
    “…BACKGROUND: Term pregnancy-induced labor refers to the use of artificial methods to induce uterine contractions and terminate pregnancy after 37 wk. It is a common method to prevent overdue pregnancy and to deal with high-risk pregnancies. …”
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    Birthing ball on promoting cervical ripening and its influence on the labor process and the neonatal blood gas index
  4. 89144
    “…Automated DNA sequencing was performed using BigDye Terminator v3.1 Cycle Sequencing Kit on 3130 Genetic Analyzer (Applied Biosystems, USA). …”
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    Disproportionate Distribution of HBV Genotypes A and D and the Recombinant Genotype D/E in the High and Low HBV Endemic Regions of Uganda: A Wake-Up Call for Regional Specific HBV Management
  5. 89145
    “…Archived tissue fluid samples were used from a prior investigation in which 6 wk-old lupus-prone female NZBWF1 mice were fed isocaloric diets containing 0 or 10 g/kg DHA for 2 wks and then intranasally instilled with 1 mg cSiO(2) or vehicle once weekly for 4 wks. Cohorts were terminated at 1, 5, 9 or 13 wk post-instillation (PI). …”
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    Silica Induction of Diverse Inflammatory Proteome in Lungs of Lupus-Prone Mice Quelled by Dietary Docosahexaenoic Acid Supplementation
  6. 89146
    “…The different extract treated groups (C, D, E, F, G) displayed a substantial neuroprotective effect regarding remyelination of axonal terminals and oligodendrocytes migration, reduced lymphocytic infiltrations, and reduced necrosis of Purkinje cells. …”
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    In Vivo Assessment of the Ameliorative Impact of Some Medicinal Plant Extracts on Lipopolysaccharide-Induced Multiple Sclerosis in Wistar Rats
  7. 89147
    “…Despite factors like high human development index (HDI), access to the Internet and social media, access to affordable healthcare, etc., factors like high population density, airports, seaports, railway stations, container terminals, IT parks, major highways, tourist spots, beaches, large shopping malls, large floating population, a huge number of migrant labourers, a large proportion of the elderly population, high prevalence of non-communicable diseases, etc., are the some of the major challenges. …”
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    COVID-19: Situation analysis in the district of Ernakulam
  8. 89148
    “…On average, surgery was performed 3.9 years after chemo and/or radiotherapy termination, except for 1 patient for whom the tympanoplasty was performed during chemotherapy treatment. …”
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    Special Considerations for Tympanoplasty Type I in the Oncological Pediatric Population: A Case-Control Study
  9. 89149
    “…Approximately one-third of patients had a new hospital or outpatient clinic contact for AF during the 3-year follow-up, suggesting that AF triggered by acute infections is not a transient, self-terminating condition that reverses with resolution of the infection.…”
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    Thromboembolic Risk in Patients With Pneumonia and New-Onset Atrial Fibrillation Not Receiving Anticoagulation Therapy
  10. 89150
    “…No neuronal death and disruption of dopaminergic terminals were detected. L-AA and a-MT-treated animals’ distance traveled was significantly (P=0.047) shorter than the Sham-operated group injected with a-MT. …”
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    The Influence of Striatal Astrocyte Dysfunction on Locomotor Activity in Dopamine-depleted Rats
  11. 89151
    “…Higher educational level [AOR = 3.62; 95% CI 2.25, 4.46], wanted pregnancy [AOR = 2.51; 95% CI 1.82, 3.12], history of terminated pregnancy [AOR = 3.21; 95% CI 2.86, 4.21], distance to the nearby health facility [AOR = 2.11; 95% CI 1.68, 2.36], women as primary decision maker [AOR = 2.15; 95% CI 2.02, 2.87], nouse of traditional medication during pregnancy [AOR = 1.01; 95% CI 1.00, 1.45], antenatal care (ANC) visit within second trimester [AOR = 2.76; 95% CI 2.01, 3.47], informed about pregnancy complication [AOR = 2.73; 95% CI 2.10, 3.21], healthcare provider support [AOR = 1.77; 95% CI 1.02, 2.44], and being eastern and western African [AOR = 1.55; 95% CI 1.11, 2.44 and AOR = 2.01; 95% CI 1.88, 2.76, respectively] were determinant factors of completion of maternity continuum of care. …”
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    Pooled Prevalence and Determinants of Completion of Maternity Continuum of Care in Sub-Saharan Africa: A Multi-Country Analysis of Recent Demographic and Health Surveys
  12. 89152
    “…Application of α‐DTX to the lungs ex vivo elicits AP discharges in about half of bronchopulmonary nodose C‐fibre terminals. Our novel finding that I (D) channels act as a critical brake on the activation of bronchopulmonary vagal afferent nerves suggests that their down‐regulation, as occurs in various inflammatory diseases, may contribute to the enhanced C‐fibre activity in airway inflammation associated with excessive respiratory symptoms.…”
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    K(V)1/D‐type potassium channels inhibit the excitability of bronchopulmonary vagal afferent nerves
  13. 89153
    “…On T cells from healthy donors the expression was limited to effector memory and terminally differentiated T cells. Notably, GPR56 expression further increased on TILs upon T cell receptor (TCR)-mediated stimulation in co-cultures with cancer cells, whereas GPR56 expression on healthy primary human T cells did not. …”
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    The Novel Immune Checkpoint GPR56 Is Expressed on Tumor-Infiltrating Lymphocytes and Selectively Upregulated upon TCR Signaling
  14. 89154
    “…Prenatal diagnosis suggested compound heterozygous mutations of c.217C>T and c.1894C>T in the fetus, indicating a high risk of INAD, and the parents chose to terminate the pregnancy. CONCLUSION: We identified a novel pathogenic mutation that broadens the mutation spectrum of PLA2G6 and will provide clues for the molecular diagnosis of INAD. …”
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    Identification of a Novel Nonsense Mutation in PLA2G6 and Prenatal Diagnosis in a Chinese Family With Infantile Neuroaxonal Dystrophy
  15. 89155
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    Dupilumab Treatment in Children Aged 6–11 Years With Atopic Dermatitis: A Multicentre, Real-Life Study
  16. 89156
    “…Treatment was generally well tolerated, and there were no Treatment emergent adverse events (TEAEs) with a toxicity grade equal to or exceeding 3 or that led to termination of treatment or patient death.Over the treatment interval of bevacizumab therapy from week 3 to week 10, patients with a large decrease of SUVmean was associated with a better PFS with a hazard ratio (HR) of 6.562, 95% CI (1.318-32.667), p=0.022. …”
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    Potential (18)F-RGD PET/CT and DCE-MRI Imaging-Based Biomarkers for Postoperative Survival Prediction Among Patients With Newly Diagnosed Glioblastoma Treated With Bevacizumab and Chemoradiotherapy
  17. 89157
    “…A total of eight variant-induced transcripts were characterized, three of which (∆(E1q17), ∆(E3p11), and ∆(E3)) were predicted to introduce a premature termination codon and to undergo nonsense-mediated decay, and five (▼(E1q9), ∆(E2p6), ∆(E2), ▼(E3q48)-a, and ▼(E3q48)-b) maintained the reading frame. …”
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    Splicing Analysis of 16 PALB2 ClinVar Variants by Minigene Assays: Identification of Six Likely Pathogenic Variants
  18. 89158
    “…Asked to identify a primary motivation, 40.3% reported feeling low risk for COVID-19 infection due to mild symptoms or vaccination, 21.2% reported a workplace culture issue (ie, increasing colleague workload, perception of weakness, responsibility for patients), 20.6% reported sick leave availability and use (including difficulty finding coverage) and 17.8% reported employment record ramifications including termination. Conclusions: This survey coincided with 2the onset of the SARS-CoV-2 ο (omicron) variant locally, and as such, risk perceptions and motivations for presenteeism may have changed. …”
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    Stay home, save lives: Characterizing sickness presenteeism and motives among healthcare personnel in the COVID-19 pandemic
  19. 89159
    por Beltsevich, Dmitry, Roslyakova, Anna
    Publicado 2022
    “…At this point, the patient and her partner were informed of the possible teratogenic effect of mitotane and strongly advised to terminate the pregnancy, but they decided to continue the pregnancy. …”
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    ODP597 Clinical case of uncomplicated pregnancy in a patient with adrenocortical carcinoma during treatment with mitotane
  20. 89160
    “…Of 3,600 subjects enrolled, 3,515 (97.64%) subjects completed the study and 85 (2.36%) terminated the study prematurely. A total of 277 adverse events occurred in 258 subjects (7.28%). …”
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    Safety and efficacy of compound methyl salicylate liniment for topical pain: A multicenter real-world study in China
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