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89161Randomized Phase 3 Trial of Ruxolitinib for COVID-19–Associated Acute Respiratory Distress Syndrome*por Rein, Lindsay, Calero, Karel, Shah, Ronak, Ojielo, Charles, Hudock, Kristin M., Lodhi, Saba, Sadaka, Farid, Bellam, Shashi, Palma, Christopher, Hager, David N., Daniel, Jeannie, Schaub, Richard, O’Hayer, Kevin, Theodoropoulos, Nicole M.“…CONCLUSIONS: The observed reduction in 28-day mortality rate between ruxolitinib and placebo in mechanically ventilated patients with COVID-19–associated acute respiratory distress syndrome was not statistically significant; however, the trial was underpowered owing to early termination.…”
Publicado 2022
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89162por Baxter, Emma M., McKeegan, Dorothy E. F., Farish, Marianne, Thomson, Jill R., Clutton, Richard E., Greenhalgh, Stephen N., Gregson, Rachael, Martin, Jessica E.“…To protect welfare, we worked on unconscious, terminally anesthetized pigs which were subject to detailed post-mortem examinations by a specialized porcine veterinary pathologist. …”
Publicado 2022
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89163por López González, Ana, Del Barco Berrón, Sonia, Grau, Isabel, Galan, Maria, Castelo Fernández, Beatriz, Cortés, Alfonso, Sánchez Rovira, Pedro, Martinez-Bueno, Alejandro, Gonzalez, Xavier, García, Almudena, Gener, Petra, Mina, Leonardo, Alcalá-López, Daniel, Sampayo, Miguel, Cortés, Javier, Pérez-Garcia, José Manuel, Llombart-Cussac, Antonio, López-Miranda, Elena“…Results: Twenty-two patients were enrolled (15 eribulin + AI arm; 7 eribulin arm). The trial was terminated early in March 2021, with eight (36.4%) patients still on treatment. …”
Publicado 2022
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89164por Rajendraprasad, Sanu, Wheeler, Molly, Wieruszewski, Erin, Gottwald, Joseph, Wallace, Lindsey A., Gerberi, Danielle, Wieruszewski, Patrick M, Smischney, Nathan J“…After starting clonidine, patients remained on dexmedetomidine for a median of 1-28 h. Following the termination of dexmedetomidine, two trials tapered enteral clonidine by increasing the interval every 24 h from 6 h to 8h, 12h, and 24 h, followed by clonidine discontinuation. …”
Publicado 2023
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89165por Kollu, Raja, Uligada, Seema, Kotamraju, Sai, Nethi Balingari, Bhavana Lakshmi, Dudekula, Anees, Kumar, Prashanth, Patil, Chandrashekar, Gaddalay, Shubham, Gaddalay, Saumya L“…Introduction Proximal interruption of pulmonary artery (PIPA) is a congenital anomaly presenting with aberrant termination of the pulmonary artery at the hilum. It results in a variety of radiological and clinical manifestations. …”
Publicado 2022
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89166por Sørensen, Juliane, Cuenca, Argelia, Olsen, Anne Berit, Skovgaard, Kerstin, Iburg, Tine Moesgaard, Olesen, Niels Jørgen, Vendramin, Niccolò“…Samples were collected from all experimental groups every 2nd week post challenge (WPC) up until trial termination at 12 WPC. PRV-3 RNA load measured in heart tissue of cohabitants peaked at 6 WPC for animals maintained at 12 and 18°C, while it reached its peak at 12 WPC in fish maintained at 5°C. …”
Publicado 2023
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89167por Olexa, Jakub“…The position readings from selected front-ends are also used by the LHC interlock system which terminates operation with beams if the beam positions exceed safe limits. …”
Publicado 2018
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89168“…An efficient method IUBCList is developed on the top of BCList++, together with a couple of pruning techniques, including common neighbor refinement and search branch early termination, to discard unpromising uncertain ([Formula: see text] , [Formula: see text] )-bicliques early. …”
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89169por Moniruzzaman, Mohammad, Kim, Dahye, Kim, Hyunsoo, Kim, Nayoung, Chin, Sungyeon, Karthikeyan, Adhimoolam, Han, Kyuhyuk, Min, Taesun“…At the end of the experiment, pigs fed the CN supplemented diet showed no significant difference in WG, ADFI or FCR compared to those on the CON diet. Overall, at the termination of the 40-day feeding trial, dietary CN had a significant effect on FW and WG, except for ADFI and FCR, in finishing pigs. …”
Publicado 2023
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89170“…The main reason for platforms disappearing was the termination of research projects. No statistically significant differences were found in functional characteristics between available and unavailable platforms. …”
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89171“…Exclusion criteria were breech presentation, cesarean section birth, instrumental delivery, multiple pregnancy, delivery before 24 + 6 weeks of gestation (WG) and termination of pregnancy for medical reasons. Women from the database were divided into two groups: an "in utero fetal death" (IUFD) group and a control group. …”
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89172por Zech, James M, Johnson, Morgan, Pullmann, Michael D, Hull, Thomas D, Althoff, Tim, Munson, Sean A, Fridling, Nicole, Litvin, Boris, Wu, Jerilyn, Areán, Patricia A“…Notably, every participant in the focus groups indicated that their ability to connect with their therapist was among the most important factors that were considered in continuing or terminating treatment. CONCLUSIONS: Engagement in messaging therapy may be usefully approached through an interdisciplinary lens, linking constructs from health science, human-computer interaction studies, and clinical science in an integrative engagement framework. …”
Publicado 2023
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89173“…Each patient underwent alternating optimisation algorithms where they were subjected to 8 transitions between a reference AV delay of 120ms and a tested AV delay ranging from 40ms to 280 ms. Testing was terminated after the AV delay occurred when native conduction occurred i.e after they began AAI pacing. …”
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89174por Wichterle, D, Peichl, P, Stojadinovic, P, Haskova, J, Borisincova, E, Sevcik, A, Sincakova, E, Kotyza, V, Cihak, R, Kautzner, J“…Substrate mapping/ablation was performed primarily during spontaneous rhythm or right-ventricular pacing. Induced VTs were terminated by overdrive pacing or cardioverted. Activation and entrainment mapping were used rarely – only in well-tolerated VTs. …”
Publicado 2023
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89175por Meijer, I, Keshtkar, S, Kong, X, Jiang, C, Ma, C, Camara, O, Marquering, H, Arrarte Terreros, N, De Groot, J“…Patients underwent 6 to 12-month follow-up and were classified as persistent (AF lasting longer than 7 days and usually requiring electrical cardioversion) and paroxysmal (self-terminating AF episodes, lasting shorter than 7 days, mostly shorter than 24 hours). …”
Publicado 2023
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89176por Alderete, J, Penela, D, Soto-Iglesias, D, Marti-Almor, J, Falasconi, G, Teres, C, Viveros, D, Bellido, A, Franco, P, Scherer, C, Francia, P, Ordonez, A, Huguet, M, Ortiz-Perez, J, Berruezo, A“…All but 1 LAAW flutter terminated during radiofrequency (RF) energy applications and rendered it non-inducible. …”
Publicado 2023
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89177por Podlogar, V, Prolic Kalinsek, T, Topalovic, M, Stublar, J, Kuhelj, D, Lakic, N, Jan, M“…Cryomapping during ongoing AVNRT was possible in 52.3% (67/128) of cases, with mean time to termination of 13.4 ± 6.5 s. Mean procedural time was 80.9 ± 39.3 minutes. …”
Publicado 2023
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89178“…In the LID-guided group (n=35) energy was delivered using an ablation catheter with local impedance monitoring. Ablation was terminated when LID reached a plateau (Fig. A). In the LSI-guided group (n=31) lesions were created using an ablation catheter with contact force monitoring until the target LSI was reached in each point (LSI=5 for anterior and LSI=4 for posterior segments, respectively, Fig B). …”
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89179“…In the LID-guided group (n=35) energy was delivered using IntellaNav MiFi (Boston Scientific, MA, USA) ablation catheter. Ablation was terminated when LID reached a plateau (Figure A). In the LSI-guided group (n=31) lesions were created using Tacticath (Abbott, MA, USA) ablation catheter until the target LSI was reached in each point (LSI=5 for anterior and LSI=4 for posterior segments respectively, Figure B). …”
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89180por Longtine, Mark S., Shim, Kyuhwan, Hoegger, Mark J., Benabdallah, Nadia, Abou, Diane S., Thorek, Daniel L.J., Wahl, Richard L.“…Low- and high-dose [(225)Ac]Ac-ofatumumab profoundly (P < 0.05) extended median survival to 190 d and more than 200 d (median not determinable), with 5 and 9 of 10 mice, respectively, surviving at study termination with no detectable cancer cells. Surviving mice treated with high-dose [(225)Ac]Ac-ofatumumab showed reduced weight gain versus naïve mice. …”
Publicado 2023
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