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  1. 89501
    “…Exclusion criteria are: 1) previous allergic reaction to plasma exchange or its ingredients (i.e., sodium citrate), 2) two consecutive negative RT-PCR tests for SARS-CoV-2 at least 24 hours apart, 3) mild COVID-19 not requiring ICU admission and 4) terminally ill patients receiving palliative care. The primary site will be King Saud Medical City (KSMC), Riyadh, Kingdom of Saudi Arabia (KSA). …”
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    A pilot study of therapeutic plasma exchange for serious SARS CoV-2 disease (COVID-19): A structured summary of a randomized controlled trial study protocol
  2. 89502
    “…The codes of the intervention will be kept in lock & key at the CTU and will only be revealed at the end of study or if the study is terminated prematurely. NUMBERS TO BE RANDOMISED (SAMPLE SIZE): As there is no prior work on this research question, so no assumptions for the sample size calculation could be made. …”
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    A quadruple blind, randomised controlled trial of gargling agents in reducing intraoral viral load among hospitalised COVID-19 patients: A structured summary of a study protocol for a randomised controlled trial
  3. 89503
    “…In some cases, the inflammation self terminates but loss of subcutaneous tissue and asymmetrical facial development remains. …”
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    O22 An inflammatory journey from brain to skin: a case of En Coupe De Sabre scleroderma presenting with raised intracranial pressure, seizures, and uveitis
  4. 89504
    “…LIMITATIONS, REASONS FOR CAUTION: The study was terminated prematurely due to slow recruitment and trial fatigue. …”
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    Uterine bathing with sonography gel prior to IVF/ICSI-treatment in patients with endometriosis, a multicentre randomised controlled trial
  5. 89505
    “…MTD to the liver is greater than 28 Gy, but the MTD was not reached as the study was terminated due to unexpected discontinuation of availability of the therapeutic agent. …”
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    Prospective SPECT-CT Organ Dosimetry-Driven Radiation-Absorbed Dose Escalation Using the In-111 ((111)In)/Yttrium 90 ((90)Y) Ibritumomab Tiuxetan (Zevalin(®)) Theranostic Pair in Patients with Lymphoma at Myeloablative Dose Levels
  6. 89506
    “…In terms of the pregnancy outcomes, 9 women had spontaneous abortions, 3 terminated their pregnancies, and 327 have ongoing pregnancies. …”
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    COVID-19 vaccination in pregnancy: early experience from a single institution
  7. 89507
    por Alveyn, Edward, Mahto, Arti
    Publicado 2021
    “…Surgical pregnancy termination was performed in accordance with patient wishes, with subsequent reversion to warfarin anticoagulation. …”
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    O21 A case of thromboembolic ischaemic cardiomyopathy and intracardiac thrombus in a patient with antiphospholipid syndrome
  8. 89508
    por Kojic, Zvezdana Zivorad
    Publicado 2020
    “…In the course of twelve-week the male Chinchilla rabbits (n = 10/group) received once a day a single dose, in group: A - sunflower oil (control animals); B – atherogenic 2% hypercholesterolemic diet; C - atherogenic diet and ramipril (1 mg/kg) and D - ramipril (1 mg/kg) only. Animals were terminated in accordance with the U.K. “Animals (Scientific Procedures) Act.” …”
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    4263 The cardioprotective effects of ramipril during the course of experimental hypercholesterolemia in rabbits
  9. 89509
    “…RESULTS: A total of 43 subjects were enrolled; the 1000 mg q24h cohort was terminated early due to local COVID restrictions. Overall, 80.6% EBO subjects and 83.3% placebo subjects experienced ≥1 TEAE, none of which was serious or severe (Table). …”
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    1727. Phase 1b Dose-ranging Study Demonstrates Tolerability and Pharmacokinetics (PK) of Oral Epetraborole at the Predicted Therapeutic Dosage for Mycobacterium avium Complex (MAC) Lung Disease
  10. 89510
    “…It concludes that these emotional configurations should be considered, by health teams and society, as part of the integral health cause for the legal interruption of pregnancy.Keywords: Unwanted pregnancy, Mental health, Legal termination of pregnancy, Argentina Expériences émotionnelles et significations autour de la grossesse non désirée/ avortement volontaire. …”
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    Experiencias emocionales y significaciones en torno al embarazo no deseado/aborto voluntario. Aportes a los alcances de la causal salud integral para la interrupción legal del embarazo en Argentina
  11. 89511
    “…At steady state, double and triple doses of icodec and glargine U100 were administered followed by hypoglycaemia induction: first, euglycaemia was maintained at 5.5 mmol/l by variable i.v. infusion of glucose; glucose infusion was then terminated, allowing PG to decrease to no less than 2.5 mmol/l (target PG(nadir)). …”
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    Hypoglycaemia frequency and physiological response after double or triple doses of once-weekly insulin icodec vs once-daily insulin glargine U100 in type 2 diabetes: a randomised crossover trial
  12. 89512
    “…Study enrollment was terminated early for administrative reasons in light of the evolving pandemic. …”
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    LB1. Remdesivir for the Treatment of High-Risk Non-Hospitalized Individuals With COVID-19: A Randomized, Double-Blind, Placebo-Controlled Trial
  13. 89513
    “…The TRAPS study compared rivaroxaban to warfarin in those with triple antibody positive antiphospholipid syndrome. The study was terminated early given that higher adverse events were observed in the rivaroxaban arm (19%, n = 11/59) versus warfarinised patients (3%, n = 2/61). …”
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    O25 Catastrophic antiphospholipid crisis triggered by anticoagulant switch
  14. 89514
    por Seetharaman, Kavita
    Publicado 2021
    “…Thyrotoxic Periodic Paralysis (TPP) is an emergency associated with flaccid paralysis in which the paralysis is reversible with prompt potassium replacement and the attacks are terminated when hyperthyroidism is cured. Timely diagnosis and treatment are therefore prudent. …”
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    Thyrotoxic Periodic Paralysis
  15. 89515
    por Goldenberg, Larry
    Publicado 2014
    “…The study did show an increase in upper and lower limb strength but was terminated prematurely due to an increased cardiovascular event rate in men receiving T. …”
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    AB19. Testosterone replacement therapy: how safe is it?
  16. 89516
    “…Experimental arms may be terminated for futility, efficacy or toxicity before the end of the trial. …”
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    Home Treatment of Older People with Symptomatic SARS-CoV-2 Infection (COVID-19): A structured Summary of a Study Protocol for a Multi-Arm Multi-Stage (MAMS) Randomized Trial to Evaluate the Efficacy and Tolerability of Several Experimental Treatments to Reduce the Risk of Hospitalisation or Death in outpatients aged 65 years or older (COVERAGE trial)
  17. 89517
    “…FINDINGS: Between Feb 15 and April 2, 2021, 262 participants (150 [57%] participants aged 12–17 years and 112 [43%] aged 6–11 years; due to the change in the UK vaccination policy, the study terminated recruitment of the younger age group before the planned number of participants had been enrolled) were randomly assigned to receive vaccination with two doses of either ChAdOx1 nCoV-19 (n=211 [n=105 at day 28 and n=106 at day 84]) or control (n=51 [n=26 at day 28 and n=25 at day 84]). …”
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    Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine in children aged 6–17 years: a preliminary report of COV006, a phase 2 single-blind, randomised, controlled trial
  18. 89518
    por Akova, Murat, Unal, Serhat
    Publicado 2021
    “…The study would be terminated if more than 15% of the subjects have grade ≥3 adverse events related to vaccination including local reactions. …”
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    A randomized, double-blind, placebo-controlled phase III clinical trial to evaluate the efficacy and safety of SARS-CoV-2 vaccine (inactivated, Vero cell): a structured summary of a study protocol for a randomised controlled trial
  19. 89519
    “…Safety was evaluated through Day 57. The study was terminated early due to low enrollment (no safety concerns). …”
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    LB4. Casirivimab and Imdevimab for Treatment of Hospitalized Patients With COVID-19 Receiving Low Flow or No Supplemental Oxygen
  20. 89520
    “…Nous avons recueilli des sérologies post-vaccination contre le SARS-COV-2 pour les PVVIH ayant terminé un schéma vaccinal avec deux doses réalisées entre le 5 mars 2021 et 17 septembre 2021. …”
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    Altération de la réponse vaccinale contre la COVID-19 dans l'infection à VIH avancée
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