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  1. 1381
    “…The outer layer of the skin, the epidermis, is the principal barrier to the external environment: post-mitotic cells terminally differentiate to form a tough outer cornified layer of enucleate and flattened cells that confer the majority of skin barrier function. …”
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    Perspective: Controlling Epidermal Terminal Differentiation with Transcriptional Bursting and RNA Bodies
  2. 1382
    “…Of particular interest is Telacebec (Q203), a phase 2 drug candidate inhibitor of the cytochrome bcc:aa(3) terminal oxidase. A functional redundancy between the cytochrome bcc:aa(3) and the cytochrome bd oxidase protects M. tuberculosis from Q203‐induced death, highlighting the attractiveness of the bd‐type terminal oxidase for drug development. …”
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    Dual inhibition of the terminal oxidases eradicates antibiotic‐tolerant Mycobacterium tuberculosis
  3. 1383
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    Intracellular Acidification Suppresses Synaptic Vesicle Mobilization in the Motor Nerve Terminals
  4. 1384
    “…C-terminal binding proteins (CtBPs) are transcriptional modulators that can regulate gene expression through the recruitment of a corepressor complex composed of chromatin-modifying enzymes and transcriptional factors. …”
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    C-Terminal Binding Proteins Promote Neurogenesis and Oligodendrogenesis in the Subventricular Zone
  5. 1385
    “…In recent years, the development of novel optical methods such as genetically encoded calcium indicators and photo-modulation of ion channel activity by pharmacological tools has provided an invaluable opportunity to directly assess nociceptive TRP channel function at the nerve terminal.…”
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    Optical Assessment of Nociceptive TRP Channel Function at the Peripheral Nerve Terminal
  6. 1386
    “…This analysis indicates that transient replication fork pausing occurs at the transcription termination sites of highly expressed genes enriched in R-loops and prevents head-on conflicts with transcription, in a topoisomerase I-dependent manner.…”
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    Topoisomerase I prevents transcription-replication conflicts at transcription termination sites
  7. 1387
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    Symmetrical arrangement of proteins under release-ready vesicles in presynaptic terminals
  8. 1388
    “…By using histone H3 mutants, we find that Rtt109-dependent N-terminal acetylation regulates fork velocity, whereas K56 acetylation contributes to replication dynamics only when N-terminal acetylation is compromised. …”
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    Rtt109 slows replication speed by histone N-terminal acetylation
  9. 1389
    “…An increased frequency of pancreatic cancer was found in families where c.9976A>T occurred together with other pathogenic BRCA1 variants. The C-terminal stop codon variants showed no association with other pathogenic BRCA2 variants. …”
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    Application of Multilayer Evidence for Annotation of C-Terminal BRCA2 Variants
  10. 1390
    por Kar, Akhya Kumar
    Publicado 2021
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    Gas pipeline error: Time to verify all the terminal central outlets?
  11. 1391
    “…A by-product of this work is that almost surely terminating deterministic (S)PCF programs with real parameters denote functions that are almost everywhere differentiable. …”
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    Densities of Almost Surely Terminating Probabilistic Programs are Differentiable Almost Everywhere
  12. 1392
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    KCC2 Chloride Transport Contributes to the Termination of Ictal Epileptiform Activity
  13. 1393
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    Therapeutic Futility in Terminal Cancer Patients: A Retrospective and Observational Study
  14. 1394
    “…These structures are capped by terminal Schwann cells (tSCs), which play essential roles during formation and maintenance of the NMJ. tSCs are implicated in the correct communication between nerves and muscles, and in reinnervation upon injury. …”
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    Terminal Schwann Cell Aging: Implications for Age-Associated Neuromuscular Dysfunction
  15. 1395
    “…In this work, based on a model of 2.5 MeV/30 mA proton accelerator, the Monte Carlo simulation software MCNPX was employed to design multi-terminal BSAs. All parameters for both the thermal and epithermal neutron beams at the exit ports of the designed BSAs meet the treatment recommendation values proposed by the International Atomic Energy Agency (IAEA). …”
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    Design of Beam Shaping Assemblies for Accelerator-Based BNCT With Multi-Terminals
  16. 1396
    “…Mechanical homeostasis plays critical roles in the initiation and termination of organogenesis, tissue repair and organ regeneration in coordination with cytokine networks.…”
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    Mechanical homeostasis of liver sinusoid is involved in the initiation and termination of liver regeneration
  17. 1397
    “…Therefore, the aim of this study was to propose two termination criteria that have been (partly) developed in other fields, but are new in animal breeding, and to compare their behavior to that of the two termination criteria widely used in animal breeding for the PCG method applied to ssSNPBLUP. …”
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    Convergence behavior of single-step GBLUP and SNPBLUP for different termination criteria
  18. 1398
    por Malik, Radek, Svoboda, Petr
    Publicado 2021
    “…RNAi appears inactive in mammalian cells except for mouse oocytes, where high RNAi activity exists because of an N-terminally truncated Dicer isoform, denoted Dicer(O). …”
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    CRISPR-Induced Expression of N-Terminally Truncated Dicer in Mouse Cells
  19. 1399
    “…INTRODUCTION: Serum N-terminal pro–B-type natriuretic peptide (NT-proBNP) levels have been associated with the progression of kidney impairment among patients with chronic kidney disease (CKD), but only a few studies have investigated the association between serum NT-proBNP levels and incident CKD in general populations. …”
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    N-Terminal Pro–B-Type Natriuretic Peptide and Incident CKD
  20. 1400
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    Giantin is required for intracellular N-terminal processing of type I procollagen
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