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1621
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1622“…The stent fractured with the distal fragment migrating as far as the terminal ileum where it caused perforation of the bowel.…”
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1623por Poyurovsky, Masha V., Katz, Chen, Laptenko, Oleg, Beckerman, Rachel, Lokshin, Maria, Ahn, Jinwoo, Byeon, In-Ja L., Gabizon, Ronen, Mattia, Melissa, Zupnick, Andrew, Brown, Lewis M., Friedler, Assaf, Prives, Carol“…The p53 tumor suppressor interacts with its negative regulator Mdm2 via the former’s N-terminal region and core domain. Yet the extreme p53 C-terminal region contains lysine residues ubiquitinated by Mdm2 and can bear post-translational modifications that inhibit Mdm2–p53 association. …”
Publicado 2010
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1624por Snow, Jonathan W., Kim, Jonghwan, Currie, Caroline R., Xu, Jian, Orkin, Stuart H.“…However, SUMOylation of FOG1 modulates interactions with C-terminal binding protein family members, specifically promoting CTBP1 binding. …”
Publicado 2010
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1625“…Hence, we predict that a large pool of dissociated rhs C-terminal tips exists episomally and these are potentially transmitted across taxonomic boundaries.…”
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1626por Hoke, Stephen M. T., Irina Mutiu, A., Genereaux, Julie, Kvas, Stephanie, Buck, Michael, Yu, Michael, Gloor, Gregory B., Brandl, Christopher J.“…Tra1 is a component of the Saccharomyces cerevisiae SAGA and NuA4 complexes and a member of the PIKK family, which contain a C-terminal phosphatidylinositol 3-kinase-like (PI3K) domain followed by a 35-residue FATC domain. …”
Publicado 2010
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1627“…DNA transposons are typically bounded by terminal inverted repeats (TIRs). Ectopic recombination between TIRs is expected to result in DNA transposon inversions. …”
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1628por Knapp, Diana C, Serva, Saulius, D'Onofrio, Jennifer, Keller, Angelika, Lubys, Arvydas, Kurg, Ants, Remm, Maido, Engels, Joachim W“…Fluorescent 2′-deoxynucleotides containing a protecting group at the 3′-O-position are reversible terminators that enable array-based DNA sequencing-by-synthesis (SBS) approaches. …”
Publicado 2011
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1629por Ferraris, Jimena, Radl, Daniela Betiana, Zárate, Sandra, Jaita, Gabriela, Eijo, Guadalupe, Zaldivar, Verónica, Clapp, Carmen, Seilicovich, Adriana, Pisera, Daniel“…Prolactin can be cleaved to different N-terminal fragments, vasoinhibins, which are proapoptotic and antiproliferative factors for endothelial cells. …”
Publicado 2011
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1630por Orioli, Andrea, Pascali, Chiara, Quartararo, Jade, Diebel, Kevin W., Praz, Viviane, Romascano, David, Percudani, Riccardo, van Dyk, Linda F., Hernandez, Nouria, Teichmann, Martin, Dieci, Giorgio“…In vitro analysis of tDNAs with a distanced T(≥4) revealed the existence of non-canonical terminators resembling degenerate T(≥5) elements, which ensure significant termination but at the same time allow for the production of Pol III read-through pre-tRNAs with unusually long 3′ trailers. …”
Publicado 2011
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1631“…We characterized the physiological properties of these synapses and describe two distinct types of excitatory postsynaptic potentials (EPSPs) that correlate with structural properties of the specific and diffuse terminals. Synapses formed by specific terminals were found to be significantly longer than those formed by diffuse terminals. …”
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1632“…Recently, in Drosophila, we reported that odor-induced Ca(2+)-response in axon terminals of olfactory receptor neurons (ORNs) is related to odor duration. …”
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1633por Zuellig, Richard A., Bornhauser, Beat C., Amstutz, Ralf, Constantin, Bruno, Schaub, Marcus C.“…Utrophin and dystrophin present two large proteins that link the intracellular actin cytoskeleton to the extracellular matrix via the C-terminal-associated protein complex. Here we describe a novel short N-terminal isoform of utrophin and its protein product in various rat tissues (N-utro, 62 kDa, amino acids 1–539, comprising the actin-binding domain plus the first two spectrin repeats). …”
Publicado 2011
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1634
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1635por Borsini, Elena, Broggini, Gianluigi, Fasana, Andrea, Baldassarri, Chiara, Manzo, Angelo M, Perboni, Alcide D“…The reaction led to differently substituted pyrrolo[2,3-c]pyridine and pyrrolo[3,2-c]pyridine derivatives arising either from direct cyclization or from a formal rearrangement of the carboxamide group. Terminal alkynes are essential to achieve bicyclic pyrrolo-fused pyridinones by a 6-exo-dig process, while the presence of a phenyl group at the C–C triple bond promotes the 7-endo-dig cyclization giving pyrrolo-azepines.…”
Publicado 2011
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1636por Brieger, Angela, Plotz, Guido, Hinrichsen, Inga, Passmann, Sandra, Adam, Ronja, Zeuzem, Stefan“…Besides significant influence of GFP- or Red-fusion on protein expression we detected incorrect shuttling of single expressed C-terminal GFP-tagged PMS2 into the nucleus and found that C-terminal dye labeling impaired MMR function of MutLα. …”
Publicado 2012
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1637“…One of the suppressors identified was RTT103, which encodes a protein implicated in transcription termination. We show that rtt103Δ are sensitive to multiple forms of genome insults and that RTT103 is essential for recovery from DNA double strand breaks in the chromosome. …”
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1638por Villar-Garea, Ana, Forne, Ignasi, Vetter, Irene, Kremmer, Elisabeth, Thomae, Andreas, Imhof, Axel“…Here, we show that a major modification of H2B in Drosophila melanogaster is the methylation of the N-terminal proline, which increases during fly development. …”
Publicado 2012
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1639“…As a result, cyclin B1 ubiquitination terminates before reaching the threshold necessary for proteolysis.…”
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1640Structure of metabotropic glutamate receptor C-terminal domains in contact with interacting proteinspor Enz, Ralf“…In contrast to solved crystal structures of extracellular N-terminal domains of some mGluR types, only a few studies analyzed the conformation of intracellular receptor domains. …”
Publicado 2012
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