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  1. 1861
  2. 1862
  3. 1863
    por Weiss, Annita N.
    Publicado 2019
    “…These residues are hydrophilic and constitute synaptobrevin-2 C-terminal flexible region. The residue Y113 of synaptobrevin-2 flexible region was mutated to lysine and glutamate. …”
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  4. 1864
    “…The Canadian Arctic Archipelago contains >300 glaciers that terminate in the ocean, but little is known about changes in their frontal positions in response to recent changes in the ocean-climate system. …”
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  5. 1865
  6. 1866
    “…Importantly, Myb knockdown fails to override the block in myeloid differentiation in cells with biallelic N-terminal C/EBPα mutations, demonstrating for the first time that the dependency on Myb is much lower in AML with this mutational profile. …”
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  7. 1867
    “…It is the catalytically-dispensable C-terminal domain of TOP2 that is crucial in determining this isoform-specific behaviour. …”
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  8. 1868
    “…Facilitated by the availability of structural information of inhibited and activated full-length structures of one of the two homologs (Idiomarina species A28L phytochrome-activated diguanylyl cyclase (IsPadC)) and characteristic differences in photoresponses of the two homologs, we identify an important cross-talk between the N-terminal segment, containing the covalent attachment site of the chromophore, and the PHY-tongue region. …”
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  9. 1869
  10. 1870
  11. 1871
    “…[Purpose] The purpose of this study was to develop an assessment tool that reflects the ankle function during the terminal stance of gait using an inertial sensor. [Participants and Methods] Thirteen healthy males (20 limbs) participated in this study. …”
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  12. 1872
  13. 1873
    “…The pervasive nature of RNA polymerase II (Pol II) transcription requires efficient termination. A key player in this process is the cleavage and polyadenylation (CPA) factor PCF11, which directly binds to the Pol II C-terminal domain and dismantles elongating Pol II from DNA in vitro. …”
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  14. 1874
  15. 1875
    por Kim, Jeong-Mok
    Publicado 2019
    “…The ribosomal synthesis of proteins in the eukaryotic cytosol has always been thought to start from the unformylated N-terminal (Nt) methionine (Met). In contrast, in virtually all nascent proteins in bacteria and eukaryotic organelles, such as mitochondria and chloroplasts, Nt-formyl-methionine (fMet) is the first building block of ribosomal synthesis. …”
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  16. 1876
    “…Second, a BLM-specific insertion between the N-terminal helices exhibits a looping-out structure that extends at right angles to the β-wing. …”
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  17. 1877
    “…With a radiocarbon age of 12,770–12,596 cal. yBP, the youngest sample in this study represents the first E. ovodovi sample dating to the terminal Pleistocene, moving the extinction date of this species forwards considerably compared to previously documented fossils. …”
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  18. 1878
    “…Here, we describe a de novo enzymatic synthesis strategy designed for data storage which harnesses the template-independent polymerase terminal deoxynucleotidyl transferase (TdT) in kinetically controlled conditions. …”
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  19. 1879
    por Guo, Lei, Zheng, Chanjin
    Publicado 2019
    “…Most of the current research focuses on developing the item selection strategies and uses a fixed-length termination rule in CAT. Nevertheless, a variable-length termination rule is more appropriate than the fixed-length rule in order to bring out the full potential of CD-CAT. …”
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  20. 1880
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