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1901por Schiffbauer, James D., Selly, Tara, Jacquet, Sarah M., Merz, Rachel A., Nelson, Lyle L., Strange, Michael A., Cai, Yaoping, Smith, Emily F.“…The fossil record of the terminal Ediacaran Period is typified by the iconic index fossil Cloudina and its relatives. …”
Publicado 2020
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1902
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1903por Chi, Xiaoke, Nguyen, Dang, Pemberton, James M, Osterlund, Elizabeth J, Liu, Qian, Brahmbhatt, Hetal, Zhang, Zhi, Lin, Jialing, Leber, Brian, Andrews, David W“…Bim binds to these proteins via its BH3 domain and to the mitochondrial membrane by a carboxyl-terminal sequence (CTS). In cells killed by Bim, the expression of a Bim mutant in which the CTS was deleted (BimL-dCTS) triggered apoptosis that correlated with inhibition of anti-apoptotic proteins being sufficient to permeabilize mitochondria isolated from the same cells. …”
Publicado 2020
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1904“…Based on these results, we propose that proteasomes are able to target oligomers assembled from N-terminally ubiquitinated proteins. Our data suggest a possible disassembly mechanism by which N-terminal ubiquitination and the proteasome may together impede aggregate formation.…”
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1905Site-specific C-terminal dinitrophenylation to reconstitute the antibody Fc functions for nanobodiespor Hong, Haofei, Zhou, Zhifang, Zhou, Kun, Liu, Shaozhong, Guo, Zhongwu, Wu, Zhimeng“…As a proof-of-principle, an anti-human EGFR nanobody, 7D12, was selected to conduct C-terminal modification with the dinitrophenyl (DNP) hapten through Sortase A-mediated site-specific ligation. …”
Publicado 2019
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1906“…Prolonged and neglected use of an intravenous (IV) line could be limb- and life-threatening. In many terminally sick cancer patients of rural India, pain management is a major concern. …”
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1907“…In this paper, a novel T-channel field effect transistor with three input terminals (Ti-TcFET) is proposed. The channel of a Ti-TcFET consists of horizontal and vertical sections. …”
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1908por Park, Joon Sung, Lee, Jae-Young, Nguyen, Yen Thi Kim, Kang, Nae-Won, Oh, Eun Kyung, Jang, Dong Man, Kim, Hyun-Jung, Kim, Dae-Duk, Han, Byung Woo“…Especially, degradation signaling of N-terminal asparagine (Nt-Asn) in eukaryotes is initiated from its deamidation by N-terminal asparagine amidohydrolase 1 (NTAN1) into aspartate. …”
Publicado 2020
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1909“…BACKGROUND: Autoresuscitation describes the return of spontaneous circulation after termination of resuscitation (TOR) following cardiac arrest (CA). …”
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1910por Sica, Giuseppe S., Di Carlo, Sara, D'Ugo, Stefano, Arcudi, Claudio, Siragusa, Leandro, Fazzolari, Laura, Biancone, Livia, Monteleone, Giovanni, Cardi, Maurizio, Sibio, SimoneEnlace del recurso
Publicado 2020
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1911“…HSP90 interacted with the N-terminal regions of FN, which are known to be important for matrix assembly. …”
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1912por Petrlova, Jitka, Petruk, Ganna, Huber, Roland G., McBurnie, Eilish W., van der Plas, Mariena J. A., Bond, Peter J., Puthia, Manoj, Schmidtchen, Artur“…Thrombin-derived C-terminal peptides (TCPs), including a major 11-kDa fragment (TCP96), are produced through cleavage by human neutrophil elastase and aggregate lipopolysaccharide (LPS) and the Gram-negative bacterium Escherichia coli. …”
Publicado 2020
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1913por Ducros, Jacques, Larifla, Laurent, Merault, Henri, Galantine, Valérie, Bassien-Capsa, Valérie, Foucan, Lydia“…Natriuretic peptides, brain natriuretic peptide (BNP), and N-terminal probrain natriuretic peptide (NT-proBNP) are mainly known as diagnostic markers for heart failure with high diagnostic and prognostic values in the general population. …”
Publicado 2020
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1914por Lenczyk, Carsten, Roy, Dipak Kumar, Nitsch, Jörn, Radacki, Krzysztof, Rauch, Florian, Dewhurst, Rian D., Bickelhaupt, F. Matthias, Marder, Todd B., Braunschweig, Holger“…The steric and electronic properties of aryl substituents in monoaryl borohydrides (Li[ArBH(3)]) and dihydroboranes were systematically varied and their reactions with [Ru(PCy(3))(2)HCl(H(2))] (Cy: cyclohexyl) were studied, resulting in bis(σ)‐borane or terminal borylene complexes of ruthenium. These variations allowed for the investigation of the factors involved in the activation of dihydroboranes in the synthesis of terminal borylene complexes. …”
Publicado 2019
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1915por Li, ShuLong, Liu, Xin, Wei, Lai, Wang, HuiFen, Zhang, JiYang, Wei, HanDong, Qian, XiaoHong, Jiang, Ying, He, FuChu“…This study evaluated plasma proteomic profiling via an N-terminal isotope tagging strategy coupled with liquid chromatography/Fourier transform ion cyclotron resonance mass spectrometry measurement to detect liver fibrosis staging. …”
Publicado 2011
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1916por Lo, Yu-Sheng, Lin, Shing-Yen, Wang, Shiu-Mei, Wang, Chin-Tien, Chiu, Ya-Li, Huang, Tai-Huang, Hou, Ming-HonEnlace del recurso
Publicado 2013
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1917“…It is necessary to understand the signaling pathways involved in AKAV-induced apoptosis to further elucidate the molecular virology of AKAV. c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK) are mediators of apoptosis; therefore, we investigated the roles of JNK and p38 MAPK cascades in AKAV-infected cells. …”
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1918por Timani, Khalid Amine, Liao, Qingjiao, Ye, Linbai, Zeng, Yingchun, Liu, Jing, Zheng, Yi, Ye, Li, Yang, Xiaojun, Lingbao, Kong, Gao, Jingrong, Zhu, Ying“…In this report, we show that the wild type N was distributed mainly in the cytoplasm. The N-terminal of the N, which contains the NLS1 (aa38–44), was localized to the nucleus. …”
Publicado 2005
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1919por Yuan, Yuan, Cao, Chan, Wen, Maorong, Li, Min, Dong, Ying, Wu, Lijie, Wu, Jian, Cui, Tanxing, Li, Dianfan, Chou, James J., OuYang, Bo“…Here, we report a crystal structure of the N-terminal domain (NTD) of DdMCU at 1.7 Å resolution. …”
Publicado 2020
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1920por Fernández-de Gortari, Eli, Aguayo-Ortiz, Rodrigo, Autry, Joseph M., Michel Espinoza-Fonseca, L.“…There is clear evidence for regulation of SERCA activity by PLB, whose activity is modulated by phosphorylation of its N-terminal domain (residues 1–25), but there is less clear evidence for the role of this domain in PLB’s functional divergence. …”
Publicado 2020
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