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  1. 1040681
    “…Continuation of alectinib was permitted after local or gradual progression at the treating clinician’s discretion. Time-to-treatment failure (TTF) was defined as the period from the start of alectinib to discontinuation for any cause including disease progression, death, adverse events and patient’s preference. …”
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    Alectinib as first-line treatment for advanced ALK-positive non-small cell lung cancer in the real-world setting: preliminary analysis in a Chinese cohort
  2. 1040682
    “…However, 18F-FDG PET/MRI may be superior to PET/CT for the diagnosis of distant metastases in patients with advanced-stage. Therefore, it is timely and important to systematically determine the diagnostic accuracy of 18F-FDG PET/MRI compared with that of 18F-FDG PET/CT for the diagnosis of distant metastases. …”
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    Comparison of whole-body 18F-FDG PET/CT and PET/MRI for distant metastases in patients with malignant tumors: a meta-analysis
  3. 1040683
    “…A Cox-proportional hazard regression model with a stepwise variable selection process was used to identify independent risk factors associated with the time to onset of a new primary cancer. RESULTS: In total, 13,887 patients were included which comprised of 2982 (21%) SOT/HSCT, 7542 (54%) PID/SID and 3363 (24%) patients receiving TNF-i. …”
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    Cancer incidence in immunocompromised patients: a single-center cohort study
  4. 1040684
    “…BACKGROUND: Although quality of life (QOL) improves over time for most breast cancer patients after their treatment, some patients may show different patterns of QOL. …”
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    Trajectories of quality of life in breast cancer survivors during the first year after treatment: a longitudinal study
  5. 1040685
    “…METHODS: Chronic exposure to arsenic in drinking water was evaluated using monitoring data collected by the water supplier. A time-weighted average arsenic exposure was estimated for the period 2005–2010. …”
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    Long-term exposure to low-level arsenic in drinking water is associated with cause-specific mortality and hospitalization in the Mt. Amiata area (Tuscany, Italy)
  6. 1040686
    “…Guidelines from studies in large academic settings recommend registered dietitian (RD) referrals at time of diagnosis and periodic testing for micronutrient deficiencies. …”
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    Short and long-term follow-up and clinical outcomes in patients with celiac disease in a large private practice setting
  7. 1040687
    “…A trend suggestive that the educational content improved the participants' confidence and knowledge components over time was noted. Future service trips may be able to build on this initial experience to improve on ways to raise capacity while delivering direct care to regions in need.…”
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    Raising Capacity to Address Mental Health Concerns in Costa Rica
  8. 1040688
    “…The possibilities offered by tala-med to recap and reflect on the contents of consultations in a time-flexible and independent manner was perceived as an added value to the PCP consultation. …”
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    The Acceptance, Usability, and Utility of a Web Portal for Back Pain as Recommended by Primary Care Physicians: Qualitative Interview Study With Patients
  9. 1040689
    “…Patients who failed treatment had significantly larger interocular difference of BCVA at the time of initial treatment (successful group: 0.33 ± 0.29 logMAR, unsuccessful group: 0.65 ± 0.35 logMAR) and after refractive adaptation (successful group: 0.15 ± 0.13 logMAR, unsuccessful group: 0.42 ± 0.35 logMAR). …”
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    Ocular and visual perceptive factors associated with treatment outcomes in patients with anisometropic amblyopia
  10. 1040690
    “…Meanwhile, incomplete defecation, time required to defecate, and number of defecation failures per 24 h were associated with increased E. faecalis frequency. …”
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    Colonic TRPV4 overexpression is related to constipation severity
  11. 1040691
    por Zhou, Zhongzheng, Long, Yi, He, Xin, Li, Yong
    Publicado 2023
    “…In the subgroup analysis, we grouped the participant data according to differences in glucocorticoids dose and type of surgery. At the same time, we also conducted a meta-analysis on the possible infection and gastrointestinal injury caused by glucocorticoids use. …”
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    Effects of different doses of glucocorticoids on postoperative atrial fibrillation: a meta-analysis
  12. 1040692
    “…METHODS: Prospective quasi-experimental study with interrupted time-series design in the North Denmark and South Denmark regions. …”
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    Prehospital vital sign monitoring in paediatric patients: an interregional study of educational interventions
  13. 1040693
    “…METHODS: This retrospective study investigated mortality trends among US veterans with PMF in 2 time periods, pre-ruxolitinib approval (01/01/2007–12/31/2010) and post-ruxolitinib approval (01/01/2015–09/30/2018). …”
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    Trends in overall mortality among US veterans with primary myelofibrosis
  14. 1040694
    “…Analyses used mixed-effects logistic modelling adjusted for time. This study is completed and registered with ClinicalTrials.gov (NCT03671447). …”
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    Effectiveness of an intensive care telehealth programme to improve process quality (ERIC): a multicentre stepped wedge cluster randomised controlled trial
  15. 1040695
    “…RESULTS: Participants (n = 15) had median age of 90 years and mild, moderate, or severe frailty scores (n = 3, 7, or 5 respectively). Over the study time course, anti-spike antibody titers were 10-fold higher in individuals with lower frailty status (p = 0.001 and p = 0.005, unadjusted and adjusted for prior COVID-19 infection). …”
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    Frailty impacts immune responses to Moderna COVID-19 mRNA vaccine in older adults
  16. 1040696
    por Wei, Li, Zhao, Dongsheng
    Publicado 2022
    “…Combined with database prediction, dual luciferase reporter assays were used to validate toll-like receptor 4 (TLR4) as a downstream target molecule of miR-145-5p. A real-time quantitative polymerase chain reaction (RT-qPCR) analysis and western blot were used to detect the expression of TLR4 in the AC16 cells. …”
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    M2 macrophage-derived exosomal miR-145-5p protects against the hypoxia/reoxygenation-induced pyroptosis of cardiomyocytes by inhibiting TLR4 expression
  17. 1040697
    “…Patients were included in the analysis if they had undergone a blood culture test within 48 hours of hospitalization with a concomitant procalcitonin assay (time < 12 hours between the two tests). Inclusion in the study began on the day of hospital admission, and each patient was followed until death, discharge from the hospital, or last known follow-up in the 50 days following hospital admission. …”
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    Usefulness of procalcitonin at admission as a risk-stratifying biomarker for 50-day in-hospital mortality among patients with community-acquired bloodstream infection: an observational cohort study
  18. 1040698
    “…CONCLUSION: Our data indicates, for the first time, that SHR is independently associated with poor long-term prognosis in patients suffering from MINOCA. …”
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    Association of stress hyperglycemia ratio and poor long-term prognosis in patients with myocardial infarction with non-obstructive coronary arteries
  19. 1040699
    por Martin, Bethany
    Publicado 2023
    “…The results help to show how the iFAST could reduce the time taken to provide critical and accurate antibiotic treatment to patients.…”
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    P20 Novel phenotypic, impedance-based fast antibiotic susceptibility test (AST) can distinguish between MRSA and MSSA in 2 h
  20. 1040700
    “…S had significant correlation with TBIL (P = 0.008, r = 0.23), age (P < 0.001, r = 0.32), international normalized ratio (INR) (P = 0.04, r = 0.23), CHE (P < 0.001, r = -0.30), PLT (P < 0.001, r = -0.40) and prothrombin time activity (PTA) (P = 0.046, r = -0.22). Multivariate logistic analysis indicated only age (95%CI=1.014~1.130, OR=1.069, P=0.013) was an impact factor for significant hepatic histopathology. …”
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    Study on pathological and clinical characteristics of chronic HBV infected patients with HBsAg positive, HBV DNA negative, HBeAg negative
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