“…INTERPRETATION: Our study demonstrates for the first time, to our knowledge, that FASN polymorphisms may predict outcome of bevacizumab-based treatment in patients with mCRC. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…There is an urgent need for more refined epidemiological methods to better understand these complex illnesses over time, to guide health policy and development-of-care. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The nasopharyngeal swabs were taken from a total number of 600 patients who were admitted to Near East University Hospital COVID-19 Polymerase Chain Reaction (PCR) Diagnosis Laboratory for routine SARS-CoV-2 real-time quantitative reverse transcription PCR (RT-qPCR) test. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To account for immortal bias, a time-dependent Cox model and landmark analyses of irAE occurrence at 1, 3, 6, and 12 months from baseline were used to estimate the hazard ratio (HR) of overall survival (OS). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…MATERIALS AND METHODS: One hundred and fifty-six patients with malignant (n = 92) and benign (n = 64) SRM were divided into the following three categories: category A, typical angiomyolipoma (AML) with visible fat; category B, benign SRM without visible fat, including fat-poor angiomyolipoma (fp-AML), and other rare benign renal tumors; category C, malignant renal tumors. At the same time, one hundred and fifty-six patients included in the study were divided into the training set (n = 108) and test set (n = 48). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Although prediabetes is an established risk factor for both macrovascular and microvascular diseases, whether prediabetes is independently associated with the risk of developing atrial fibrillation (AF), particularly the occurrence time, has not been well studied using a high-quality research design in combination with statistical machine-learning algorithms. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, using sequencing data generated in the public domain, we have established a specific regulatory network of “transcription factor (TF)-microRNA (miRNA)-Target” to provide key molecules for evaluating the passage-dependent replicative senescence of mesenchymal stem cells for the quality control and status evaluation of mesenchymal stem cells prepared by different procedures. Short time-series expression miner (STEM) analysis was performed on the RNA-seq and miRNA-seq databases of mesenchymal stem cells from various passages to reveal the dynamic passage-related changes of miRNAs and mRNAs. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Our study aimed to investigate the continuation of folic acid (FA) supplementation from pre-conception to post-conception during peri-conceptional period and to examine its differences in FA supplementation between the subgroups taking the initiation timing into consideration. METHODS: This study was conducted in two community health service centers in Jing-an District of Shanghai. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The inhibition of acid production, hydrophobicity, biofilm formation and real-time PCR for gtfB/C/D, spaP, gbpB, vicR, relA and brpA mRNA expression by S. mutans were assessed to preliminarily investigate the mechanisms of action. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Outcome measures, including community participation, quality of life, and the occurrence and subjective impact of medically serious secondary conditions and rehospitalizations, were assessed at baseline after randomization and at subsequent time points to allow between-group comparisons. RESULTS: PN hiring and training were completed in August 2018. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Global screening, leading to timely identification of DM-related complications, is insufficiently implemented by currently applied reactive medicine. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Furthermore, there is no evidence that patients presenting with these bacteria at the time of surgery are at a higher risk of failure following TAA or ankle arthrodesis.…”
Enlace del recurso
Enlace del recurso

“…An early warning outbreak recognition system (EWORS) is a system that is primarily used to detect infectious disease outbreaks; this system can be used as a case-based geospatial tool for the real-time identification of hot spot areas with clusters of TB patients. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…TPT completion was consistently high at above 70% at most of the time, but, it increased significantly among those initiated during 2018 quarter four and in the subsequent two quarters after the roll-out of the 100-day accelerated TPT intervention (i.e. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, the specific biomarkers and precise mechanisms of this disease are not fully understood, which can delay the best treatment time, hence, this study aimed to detect the potential biomarkers and pathophysiological process of KD through bioinformatic analysis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…With the STI, the inclusion of MOL reduced (linear: p ≤ 0.0199; quadratic: p ≤ 0.0267) biogas production (mL g(−1) DM incubated and degraded), CH(4) (mL g(−1) DM degraded), CO (mL g(−1) DM degraded), and H(2)S (mL g(−1) DM incubated and degraded), without affecting (p > 0.05) the parameters (b = asymptotic gas, c = rate of gas production and Lag = initial delay time before gas production) of CH(4) and H(2)S, and the proportion and production of CH(4) per kg of dry matter (DM). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…PET imaging studies in rats after intravenous (IV) administration at different doses (1 µg/Kg and 5 mg/Kg) were combined with determination of arterial blood time-activity curves (TACs) and analysis of plasma samples by high performance liquid chromatography (HPLC) to quantify radioactive metabolites. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…All subjects were exposed for assaying gene expressions of PIK3C2A and TXNIP by quantitative real-time polymerase chain reaction. Results: It was found that TXNIP was upregulated, whereas PIK3C2A was downregulated in patients with CAD compared to the control group. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The Kaplan–Meier method was used to estimate time to grade ≥ 3 toxicity, local control (LC), freedom from distant metastases (FFDM), progression-free survival (PFS), biochemical control (BC) and overall survival (OS). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The participants’ overall evaluation of the app was positive. The wake-up time was advanced (base mean 8:06 AM; post mean 7:48 AM; F(1,65)=6.769; P=.01 and sleep onset latency was decreased (base mean 34.45 minutes; post mean 20.05 minutes; F(1,65)=23.219; P<.001) significantly in the app use group at the 13th month compared with the video-only group. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso