“…Finally, the study validated the mRNA and protein expression using real-time quantitative PCR, western blotting, and immunohistochemical analysis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Fourteen of 47 (30%) eyes were given additional injections with a mean number of 5.7 ± 4.5 after the trial. At a mean follow-up time of 82 ± 5 months best corrected visual acuity (BCVA) remained stable or improved (≤ 10 letters lost) in 55% of patients in the entire study population, in 43% in the ranibizumab group and in 60% in the aflibercept group. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…At a median follow-up time of 21 months (range, 6–32 months), the median biochemical progression-free survival was 19 months (range, 4 to 23 months) in the radiotherapy group, as compared with 16.5 months (range, 4 to 28 months) in the surgery group. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To prevent the untimely suffering and death of children, regular nutrition screening, speedy, and appropriate referral of all malnourished children to nutritional services and large-scale humanitarian assistance including access to food; nutrition supplies; water, sanitation and hygiene supplies; and health care in a timely manner are required. In the prevailing armed conflict, these have been very difficult to achieve. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…PLAIN LANGUAGE SUMMARY: Development and pilot-test of a pharmacist intervention for patients in transition between hospital and general practice Background: Healthcare is challenged by a rapidly growing group of patients with multiple chronic diseases treated with several drugs at the same time. The aim of the study was to explore drug-related problems in the transition of patients between the hospital and patients’ general practitioner and to develop and pilot-test a pharmacist intervention to overcome some of these problems. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the following analysis, regression models and multivariate analysis were used to determine how students improved over time, and trajectory analysis were carried out in order to observe the trends in students’ critical thinking skills construction. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, the follow-up time point was limited to 3 months which might not be long enough for drastic mindset and behavioral changes in help-seeking to occur. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Yet, poor communication of complex topics, such as gene therapy, can be problematic, especially if patients lack the skills and confidence to understand and discuss the science, or for physicians with limited time in clinic. We propose strategies to improve the consent process, so patients can feel more able to make informed decisions about new treatments. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…There are many variations of each technique, and some are time consuming and costly. Concerns about effectiveness and safety have also rendered many of them unappealing. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…With a median follow-up period of 18.6 months, the probabilities of relapse-free survival（RFS）and overall survival（OS）at 3 years were 25.4％ and 37.3％ in patients with transplantation, and in patients with chemotherapy, the probabilities of RFS and OS at 3-year were 58.2％ and 64.3％, respectively. At the time of achieving MLFS, multivariate analysis revealed that age ≥46 years（HR＝3.4, 95％CI 1.6–7.2, P＝0.002 and HR＝2.5, 95％CI 1.1–6.0, P＝0.037）, peripheral blasts ≥17.5％ at diagnosis（HR＝2.5, 95％CI 1.2–4.9, P＝0.010 and HR＝4.1, 95％CI 1.7–9.7, P＝0.002）, monosomal karyotypes（HR＝4.9, 95％CI 1.2–19.9, P＝0.027 and HR＝28.3, 95％CI 4.2–189.5, P＝0.001）were typical adverse factors influencing RFS and OS. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…INTRODUCTION: Globally, chronic pain affects more than 30% of people worldwide and is the leading cause of disability and health care utilisation. Access to timely, person-centred, cost-effective programs is unattainable for most. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: IPOS-COV is the first patient-centred measure adapted for severe COVID to support timely management. Future studies could further evaluate its responsiveness and clinical utility with clinimetric approaches. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…On average, the older adult care partner representative rated usability issues as being more significant more of the time. In stage 3, 31 usability issues were rated by an IT professional as “impossible to address,” 21 as “maybe,” and 24 as “can be addressed.” …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To minimize the proportion of preterm birth focusing on this important variables, timely identification of obstetric complications, strengthening early screening of HIV and high-risk pregnancies like multiple gestations, PIH and APH were important.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Our primary outcome was time to first COVID-19 vaccination between December 15, 2020 and June 15, 2021. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Submaximal fitness tests (SMFT) are a pragmatic approach for evaluating athlete’s physiological state, due to their time-efficient nature, low physiological burden and relative ease of administration in team sports settings. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Using a randomized controlled design, families were randomly allocated to either an intervention group (IG; 73/136, 53.7%) or a waitlist control group (WCG; 63/136, 46.3%) during the usual waiting time until consultation. The IG was given a psychoeducational app that included evidence-based information via text and videos, a child behavior diary function, a parent chat forum and experience report, tips on relaxation, an emergency plan, and a regional directory of specialized counseling centers. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…No significant between-group baseline differences (pre-6-weeks intervention) were observed for any of the reported psychological and muscle strength parameters. Significant group-by-time interactions were found for TSK-CF (p = 0.001, d = 2.85), KOOS (p = 0.001, d = 1.31), and IKDC (p = 0.001, d = 1.07). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…A cycle length of 28 days and a time horizon of 10 years was assumed. VEN+O treatment for a fixed duration of 12 months was compared to obinutuzumab combined with chlorambucil, fludarabine plus cyclophosphamide plus rituximab, bendamustine plus rituximab, chlorambucil plus rituximab, ibrutinib, and acalabrutinib. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…SIMPLE SUMMARY: Weaning is a stressful period for pigs that causes gastrointestinal disruption and low growth rates. For a long time, zinc oxide at pharmacological doses, along with different antibiotics, has been used prophylactically during this phase to reduce the incidence of these gastrointestinal problems. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso