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1041441por Li, Jiaqi, Jin, Yu, Xu, Shicun, Wilson, Amanda, Chen, Chang, Luo, Xianyu, Liu, Yuhang, Ling, Xi, Sun, Xi, Wang, Yuanyuan“…CONCLUSIONS: For the first time, this study identified the most central and bridge symptoms (sad mood and irritability) within the depression-anxiety-PTSD network of sexual minority youths with past bullying-victim experiences on college campuses. …”
Publicado 2023
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1041442por Lin, Feng, Yang, Kang, Lin, Xin, Jin, Ming, Chen, Long, Zheng, Fu-ze, Qiu, Liang-liang, Ye, Zhi-xian, Chen, Hai-zhu, Lin, Min-ting, Wang, Ning, Wang, Zhi-qiang“…CONCLUSION: We determined the prevalence of different LGMD subtypes in Southeast China, described the detailed clinical manifestations and distinct muscle MRI patterns of these LGMD subtypes and reported the frequent mutations and the cardiorespiratory involvement frequency in our cohort, all of which might facilitate the differential diagnosis of LGMDs, allowing more timely treatment and guiding future clinical trials. …”
Publicado 2023
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1041443por Daily, Zina A., Al-Ghurabei, Batool Hassan, Al-Qarakhli, Ahmed Makki A., Moseley, Ryan“…Patient whole blood and saliva levels of miR-155 and pro-inflammatory cytokine (interleukin-1β), were quantified by quantitative real time polymerase chain reaction (qRT-PCR) and enzyme-linked immunosorbent assay (ELISA). …”
Publicado 2023
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1041444por Cross, James H., Bohne, Christine, Ngwala, Samuel K., Shabani, Josephine, Wainaina, John, Dosunmu, Olabisi, Kassim, Irabi, Penzias, Rebecca E., Tillya, Robert, Gathara, David, Zimba, Evelyn, Ezeaka, Veronica Chinyere, Odedere, Opeyemi, Chiume, Msandeni, Salim, Nahya, Kawaza, Kondwani, Lufesi, Norman, Irimu, Grace, Tongo, Olukemi O., Malla, Lucas, Paton, Chris, Day, Louise T., Oden, Maria, Richards-Kortum, Rebecca, Molyneux, Elizabeth M., Ohuma, Eric O., Lawn, Joy E.“…The NID has been implemented at 69 neonatal units in four African countries and links to a facility-level quality improvement (QI) dashboard used in real-time by facility staff. CONCLUSION: The NEST360 NID is a novel, parsimonious tool for use in routine information systems to inform inpatient SSNC quality. …”
Publicado 2023
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1041445por Veldman, M.H.J., van der Aa, H.P.A., Knoop, H., Bode, C., Hulshof, C.T.J., van der Ham, L., van Rens, G.H.M.B., Heymans, M.W., van Nispen, R.M.A.“…Adults with visual impairment and severe fatigue (n = 10) followed the intervention partially with guidance from a social worker and one-time computer trainer support. Fatigue severity (Checklist Individual Strength), fatigue impact (Modified Fatigue Impact Scale) and cognitive behavioral therapy skills (Competencies of Cognitive Therapy Scale-Self Report) were measured at baseline and at three months follow-up and analyzed with the Wilcoxon signed-rank test. …”
Publicado 2023
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1041446por Jesudason, Cynthia D., Mason, Emily R., Chu, Shaoyou, Oblak, Adrian L., Javens‐Wolfe, June, Moussaif, Mustapha, Durst, Greg, Hipskind, Philip, Beck, Daniel E., Dong, Jiajun, Amarasinghe, Ovini, Zhang, Zhong‐Yin, Hamdani, Adam K., Singhal, Kratika, Mesecar, Andrew D., Souza, Sarah, Jacobson, Marlene, Salvo, Jerry Di, Soni, Disha M., Kandasamy, Murugesh, Masters, Andrea R., Quinney, Sara K, Doolen, Suzanne, Huhe, Hasi, Rizzo, Stacey J. Sukoff, Lamb, Bruce T., Palkowitz, Alan D., Richardson, Timothy I.“…Although this compound is our recommended chemical probe for investigating the pharmacology of SHIP1 inhibition at this time, further optimization is required for clinical studies. …”
Publicado 2023
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1041447por Jarnagin, Joy X., Saraf, Anurag, Baiev, Islam, Chi, Gary, van Seventer, Emily E., Mojtahed, Amirkasra, Allen, Jill N., Clark, Jeffrey W., Blaszkowsky, Lawrence, Giantonio, Bruce J., Weekes, Colin D., Klempner, Samuel J., Franses, Joseph W., Roeland, Eric J., Goyal, Lipika, Siravegna, Giulia, Horick, Nora, Corcoran, Ryan B., Nipp, Ryan D., Parikh, Aparna R.“…INTERVENTION: PROs were collected, including QOL (Functional Assessment of Cancer Therapy General [FACT-G]), physical symptoms (Edmonton Symptom Assessment System [ESAS]), and psychological symptoms (Patient Health Questionnaire-4 [PHQ4] total, PHQ4-depression, and PHQ4-anxiety), as well as TMs (CEA and CA 19-9), at the time of chemotherapy initiation and 1 month later. …”
Publicado 2023
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1041448por Dhaliwal, Raman, Yap, Sidney, Talarico, Fernanda, Al-Shamali, Huda, Mcweeny, Robert, Reeson, Matthew, Shalaby, Reham, Chen, Teresa, Spronk, Elena, Snodgrass, Rayven, Tu, Eileen, Erick, Taylor, Marshall, Tyler, Kennedy, Megan, Greenshaw, Andrew J, Winkler, Olga, Burback, Lisa“…While these changes helped ensure timely psychotherapy provision, many concerns exist, including clinical, cultural, practical, privacy, and security issues. …”
Publicado 2023
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1041449por Lofters, Aisha K., Wu, Fangyun, Frymire, Eliot, Kiran, Tara, Vahabi, Mandana, Green, Michael E., Glazier, Richard H.“…CONCLUSIONS AND RELEVANCE: In this cross-sectional study in Ontario that included 2 time points, widening disparities before compared with after the COVID-19 pandemic were found for breast cancer and colorectal cancer screening based on income and immigrant status, but smaller declines in disparities were found among patients of interprofessional, team-based primary care models than among their counterparts. …”
Publicado 2023
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1041450por Falkai, P., Reuteman-Fowler, C., Blahova, Z., Ikezawa, S., Marder, S. R., Krystal, J. H.“…Key secondary efficacy endpoints are CfB in Schizophrenia Cognition Rating Scale total score and CfB in the adjusted total time in the Virtual Reality Functional Capacity Assessment Tool. …”
Publicado 2023
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1041451por Emmert-Fees, Karl M. F., Amies-Cull, Ben, Wawro, Nina, Linseisen, Jakob, Staudigel, Matthias, Peters, Annette, Cobiac, Linda J., O’Flaherty, Martin, Scarborough, Peter, Kypridemos, Chris, Laxy, Michael“…Resulting cases of cardiometabolic disease prevented/postponed and related quality-adjusted life years (QALYs) and economic impacts from healthcare (medical costs) and societal (medical, patient time, and productivity costs) perspectives were estimated using national cost and health utility data. …”
Publicado 2023
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1041452por Reyes, Jonathan, Spitz, Gershon, Major, Brendan P., O'Brien, William T., Giesler, Lauren P., Bain, Jesse W.P., Xie, Becca, Rosenfeld, Jeffrey V., Law, Meng, Ponsford, Jennie L., O'Brien, Terence J., Shultz, Sandy R., Willmott, Catherine, Mitra, Biswadev, McDonald, Stuart J.“…Future studies will investigate the optimal time frame over which plasma IL-6 might assist diagnostic decisions and how extracranial trauma affects utility.…”
Publicado 2023
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1041453por Peirce, Vivian, Paskow, Michael, Qin, Lei, Dadzie, Ruby, Rapoport, Maria, Prince, Samantha, Johal, Sukhvinder“…Some studies with small sample sizes or specifically selected patient populations (e.g. higher performance status, or patients who had already responded to treatment) achieved higher median overall survival. CONCLUSIONS: At the time of this review, treatment options for unresectable advanced or metastatic biliary tract cancers confer poor real-world survival. …”
Publicado 2023
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1041454por Crawshaw, Jacob, Meyer, Carly, Antonopoulou, Vivi, Antony, Jesmin, Grimshaw, Jeremy M., Ivers, Noah, Konnyu, Kristin, Lacroix, Meagan, Presseau, Justin, Simeoni, Michelle, Yogasingam, Sharlini, Lorencatto, Fabiana“…The most common BCTs were ‘Feedback on behaviour’ (present 89% of the time; e.g. feedback on drug prescribing), ‘Instruction on how to perform the behaviour’ (71%; e.g. issuing a clinical guideline), ‘Social comparison’ (52%; e.g. feedback on performance of peers), ‘Credible source’ (41%; e.g. endorsements from respected professional body), and ‘Education (unspecified)’ (31%; e.g. giving a lecture to staff). …”
Publicado 2023
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1041455por Bi, Pingping, Wang, Xi, Liu, Rui, Li, Xiuqin, Wei, Shanrong, Zhao, Jiawen, Tan, Xin, Zhang, Fan, Mao, Qing, Zhang, Ying, Tang, Baoyan, Xun, Xueqiong, Guo, Rong, Zheng, Kai, Zhou, Shaoqiang, Tang, Shicong“…BACKGROUND: The purpose of this study was to compare the efficacy and safety of utidelone plus capecitabine for advanced first-line versus second-line or above therapy in metastatic breast cancer patients who had previously received anthracycline and taxane. At the same time, we compared the efficacy of utidelone plus capecitabine and vinorelbine plus cisplatin in advanced first-line treatment of metastatic breast cancer. …”
Publicado 2023
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1041456por Chen, Wei-Jie, Gan, Chun-Xia, Cai, Yang-Wei, Liu, Yang-Yang, Xiao, Pei-Lin, Zou, Li-Li, Xiong, Qing-Song, Qin, Fang, Tao, Xie-Xin, Li, Ran, Du, Hua-An, Liu, Zeng-Zhang, Yin, Yue-Hui, Ling, Zhi-Yu“…BACKGROUND: High-power short-duration (HPSD) ablation strategy has emerged as a popular approach for treating atrial fibrillation (AF), with shorter ablation time. The utilized Smart Touch Surround Flow (STSF) catheter, with 56 holes around the electrode, lowers electrode-tissue temperature and thrombus risk. …”
Publicado 2023
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1041457por Atakpa, Emma C., Buist, Diana S. M., Aiello Bowles, Erin J., Cuzick, Jack, Brentnall, Adam R.“…Predictive ability was assessed using (1) age and body mass index-adjusted hazard ratios (HR) for breast density (time-varying covariate), (2) likelihood-ratio statistics (ΔLR-χ(2)) and (3) concordance indices. …”
Publicado 2023
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1041458por Gafen, Hannah B., Liu, Chin-Chi, Ineck, Nikole E., Scully, Clare M., Mironovich, Melanie A., Taylor, Christopher M., Luo, Meng, Leis, Marina L., Scott, Erin M., Carter, Renee T., Hernke, David M., Paul, Narayan C., Lewin, Andrew C.“…This study aimed to characterize the bovine bacterial ocular surface microbiome (OSM) through conjunctival swab samples from Normal eyes and eyes with naturally acquired, active IBK across populations of cattle using a three-part approach, including bacterial culture, relative abundance (RA, 16 S rRNA gene sequencing), and semi-quantitative random forest modeling (real-time polymerase chain reaction (RT-PCR)). RESULTS: Conjunctival swab samples were obtained from eyes individually classified as Normal (n = 376) or IBK (n = 228) based on clinical signs. …”
Publicado 2023
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1041459por Zhang, Yiyang, Zhou, Manlin, Liang, Yuxin, Li, Rui, Zhang, Lan, Chen, Shuwu, Yang, Kun, Ding, Haie, Tan, Xiao, Zhang, Qian, Qiao, Zilin“…The possible regulatory relationship between the above results and the adaptation of yak lungs to the plateau hypoxic environment paves the way for the regulatory mechanisms of PDK1, HIF-1α, and VEGF, and provides basic information for studying the mechanism of hypoxic adaptation of yaks in the plateau. At the same time, it provides a reference for human hypoxia adaptation and a target for the prevention and treatment of plateau diseases in humans and plateau animals.…”
Publicado 2023
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1041460por Durma, Adam Daniel, Saracyn, Marek, Kołodziej, Maciej, Jóźwik-Plebanek, Katarzyna, Dmochowska, Beata, Kapusta, Waldemar, Żmudzki, Wawrzyniec, Mróz, Adrianna, Kos-Kudła, Beata, Kamiński, Grzegorz“…In long-term follow-up, the median observation time among patients who underwent four treatment cycles (n = 108) was 29.8 (IQR = 23.9) months. …”
Publicado 2023
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