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1041481por Villegas, Sara I Gomez, Panesso, Diana, Singh, Kavindra, Rincon, Sandra, Carvajal, Lina Paola, Jacques-Palaz, Karen, Rizvi, Samie, Burnham, Carey-Ann, Abbott, April, Bard, Jennifer Dien, Westblade, Lars, Fritz, Stephanie A, Zimmer, Barbara, Dingle, Tanis C, Butler-Wu, Susan, Miller, William R, Reyes, Jinnethe, Arias, Cesar A“…Broth microdilution at high inoculum is the gold standard for the detection of the CzIE, but this method is time and labor-intensive. We developed a nitrocefin-based rapid test that can identify the CzIE among MSSA(Figure 1). …”
Publicado 2023
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1041482por Stewart, Laveta, Craig-Kuhn, Megan Clare, Sercy, Erica, Stern, Caryn, Graham, Brock, Michel, Amber, Parmelee, Edward, Shackelford, Stacy, Pollett, Simon, Burgess, Timothy, Tribble, David R, Tribble, David R“…Overall, 90% received >1 primary series dose; with 85% completing the primary series, 5% had partial primary series, and 10% had no record of vaccination at the end of observed time. Of SMs with >1 primary series dose, 78% received the 1st dose pre mandate (11% had COVID-19 prior to 1(st) dose) and 22% post mandate (19% had COVID-19 prior to 1(st) dose; p< 0.001) (Table 1 and Fig. 1). …”
Publicado 2023
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1041483por Fernández-Rodríguez, Diana, Tarabichi, Saad, Golankiewicz, Krystal, Zappley, Nicolina, Parvizi, Javad“…Additional surgical-related variables were also recorded at each time of sampling. Swabs were processed for culture and Next-Generation Sequencing. …”
Publicado 2023
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1041484por Dekanich, Ketrah, Smith, Kristen, Laing, Eric D, Wang, Wei, Weiss, Carol D, Samuels, Emily C, Swafford, Isabella, Paquin-Proulx, Dominic, Currier, Jeffrey R, Parsons, Emily, Richard, Stephanie A, Jones, Milissa U, Rozman, Julia, Colombo, Rhonda E, Huprikar, Nikhil, Lindholm, David, Mende, Katrin, Ganesan, Anuradha, Larson, Derek, Ewers, Evan, Flanagan, Ryan, Simons, Mark P, O’Connell, Robert, Tribble, David, Agan, Brian, Burgess, Timothy, Hickey, Patrick W, Pollett, Simon, Malloy, Allison M“…The average anti-spike IgG at time of birth from mothers who were infected versus infected and vaccinated during pregnancy was 165.5 and 2592.7 BAU/ml, respectively (p=0.006). …”
Publicado 2023
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1041485por Reveles, Kelly R, Gonzales-Luna, Anne J, Golan, Yoav, Alonso, Carolyn D, Guthmueller, Beth, Tan, Xing, Bidell, Monique, Pokhilko, Victoria, Crawford, Carl, Skinner, Andrew M“…Most participants were treated with antibiotic monotherapy (n=34/43, 79.1%), received 1 course of treatment (n=28/43, 65.1%), and did not receive CDI prophylaxis (n=38/43, 88.4%). The median time to antibiotic exposure after the second dose of RBL was 155 days (interquartile range [IQR], 55-349), and the median duration of treatment per antibiotic course was 8 days (IQR, 4.5-12.5). …”
Publicado 2023
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1041486por Zheng, Chengyi, Ackerson, Bradley, Daily, Leticia I Vega, Song, Jeannie, Sy, Lina S, Qian, Lei, Luo, Yi, Florea, Ana, Ku, Jennifer H, Cheng, Yanjun, Wu, Jun, Tseng, Hung Fu“…The criterion standard for identifying PHN in electronic health records (EHR) is manual chart review, which can be costly and time-consuming. We developed and validated a method to automatically identify PHN from free-text EHR data using natural language processing (NLP). …”
Publicado 2023
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1041487por Banerjee, Dithi, Sasidharan, Anjana, Gummersheimer, Stephanie, Petty, Sydnie, Hayes, Amanda M, Dhar, Minati, Selvarangan, Rangaraj“…All samples with initial invalid results on Xpert (5, 2%), SPOTFIRE (3, 1.2%) and Cobas (2, 0.8%) were valid on re-testing. Total hands-on time (specimen processing and loading, retrieving results) ranged between 1.13 minutes to 2.34 minutes for all assays. …”
Publicado 2023
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1041488por Bhashyam, Sumitra Sri, Shane, L G, Lewis, Hannah B, de la Cruz, Marie, Galinsky, Jayne, Demchuk, Keeva, Waite, Nancy M, Lazarus, Jeffrey V, Salisbury, David M“…Participants’ top four priorities were vaccine protection against COVID-19, serious side-effects, protection against severe COVID-19, and common side-effects, followed by vaccine type and timing of COVID-19/influenza vaccines (Fig 1). More than half of the participants would consider co-administration of COVID-19 and influenza vaccines, either as two separate injections (58.3%) or as a single, combined injection (62.5%) (Fig 2a). …”
Publicado 2023
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1041489por Schmidt, Kat, Richard, Stephanie A, Berjohn, Catherine, Lalani, Tahaniyat, Smith, Alfred, Mody, Rupal, Lindholm, David, Huprikar, Nikhil, Saunders, David, Colombo, Rhonda, Jones, Milissa, Flanagan, Ryan, Ewers, Evan, Chang, David, Schofield, Christina, Edwards, Margaret Sanchez, Maldonado, Carlos, Mende, Katrin, Scher, Ann, Rusiecki, Jennifer, Byrne, Celia, Wyatt, Andrew, Simons, Mark P, Tribble, David R, Tribble, David R, O’Connell, Robert, Agan, Brian, Burgess, Timothy, Pollett, Simon, Ganesan, Anuradha“…Controls were selected randomly and matched individually to cases on age, race, sex, and time period. We defined exposure as ≥ 1 SC2 positive test or COVID-19 vaccination 0-365 days before HZ diagnosis. …”
Publicado 2023
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1041490por Schmidt, Mark A, Kuntz, Jennifer L, Shuster, Elizabeth, Contreras, Richard, Donald, Judy L, Barreras, Joanna L, Angulo, Fredrick J, Yu, Holly, Gonzalez, Elisa, Zamparo, Joann M, Florea, Ana, Tartof, Sara Y“…Zamparo, MPH, Pfizer Inc.: Full Time Employee|Pfizer Inc.: Stocks/Bonds Ana Florea, PhD MPH, Gilead: Grant/Research Support|GlaxoSmithKline: Grant/Research Support|Moderna: Grant/Research Support|Pfizer: Grant/Research Support Sara Y. …”
Publicado 2023
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1041491“…CAR-natural killer (NK) cells do not carry the risk of inducing graft-versus-host disease (GvHD) frequently associated with allogeneic T cells, thereby overcoming time-consuming, autologous cell manufacturing, and have relatively safer clinical profiles than CAR-T cells. …”
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1041492por Chen, Hongbo, Zhong, Qian, Liu, Yujie, Li, Jinyan, Deng, Wenjing, Wang, Jie, Zhou, Shuquan, Yu, Zengrong, Huang, Xianzhan, Huang, Yuanqiong, Zhen, Bo, Wei, Jihong, Zhang, Weijian, Ruan, Xiaohong, Xiao, Lin“…RESULTS: The incidence of grade ≥ 2 leukopenia, neutropenia, thrombocytopenia and anemia in patients during radiotherapy was 63.9%, 45.4%, 19.6% and 38.8% respectively, and the median occurrence time was the 29th, 42th, 35th and 31th day, respectively. …”
Publicado 2023
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1041493por Reif, Kathryn E., Bickmeier, Naemi P., Herrin, Brian H., Dryden, Michael W., Normile, Dorothy M., Jesudoss Chelladurai, Jeba R. J., Miller, Kamilyah R., Flowers, Macy R., Kang, Qing“…Tick control efficacy was determined by comparing live tick means for each product-treated group to the untreated control group and each other at all time points using a linear mixed model. The percent of dogs free of live ticks was analyzed using the Fisher’s exact test for treatment group comparison. …”
Publicado 2023
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1041494por Zheng, Quan, Tang, Jiajia, Aicher, Alexandra, Bou Kheir, Tony, Sabanovic, Berina, Ananthanarayanan, Preeta, Reina, Chiara, Chen, Minchun, Gu, Jian-Min, He, Bin, Alcala, Sonia, Behrens, Diana, Lawlo, Rita T., Scarpa, Aldo, Hidalgo, Manuel, Sainz, Bruno, Sancho, Patricia, Heeschen, Christopher“…Assays included RNA-seq, sphere/colony formation, cell viability/toxicity, real-time PCR, western blot, immunofluorescence, ChIP, CUT&Tag, XF Analysis, lactate production, and in vivo tumorigenicity assays. …”
Publicado 2023
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1041495por Viegas, Ângela Alves, Santos, Thiago, Nobre, Juliana Nogueira Pontes, Santos, Jousielle Márcia dos, Silva Lage, Vanessa Kelly da, Fernandes, Amanda Cristina, Peixoto, Marco Fabrício Dias, Morais, Rosane Luzia De Souza, Sartorio, Alessandro, Mendonça, Vanessa Amaral, Lacerda, Ana Cristina Rodrigues“…Additionally, leptin levels were lower in OW/OB preschoolers engaged in vigorous physical activity (VPA) (8000–9999 counts/min) for longer periods of time. CONCLUSION: The results of this study indicate that OW/OB preschoolers have higher levels of oxidative stress biomarkers and pro-inflammatory cytokines compared to EU preschoolers. …”
Publicado 2023
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1041496“…The differences between the two age groups - with younger people being more open to digital solutions and using them more - and the fact that the under 65s are better adapted digitally in all respects, raises the possibility that the specific trends in digital health for older people may virtually disappear in 10 years’ time (when the under 65s now enter this age group). …”
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1041497Myocardial protection with phosphocreatine in high-risk cardiac surgery patients: a randomized trialpor Lomivorotov, Vladimir, Merekin, Dmitry, Fominskiy, Evgeny, Ponomarev, Dmitry, Bogachev-Prokophiev, Alexander, Zalesov, Anton, Cherniavsky, Alexander, Shilova, Anna, Guvakov, Dmitry, Lomivorotova, Liudmila, Lembo, Rosalba, Landoni, Giovanni“…BACKGROUND: This study was conducted to test the hypothesis that phosphocreatine (PCr), administered intravenously and as cardioplegia adjuvant in patients undergoing cardiac surgery with prolonged aortic cross clamping and cardiopulmonary bypass (CPB) time, would decrease troponin I concentration after surgery. …”
Publicado 2023
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1041498“…Furthermore, the investigational drugs in 33 studies (33/46, 71.7%) received new drug approval at the end of January 31, 2023.The time lag from the start of the compassionate use to the formal approval of the investigational drug was 790.5 (IQR 359–2199.3) days. …”
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1041499por Zhou, Jie, Yang, Xiping, Yang, Yuecong, Wei, Yiru, Lu, Dongjia, Xie, Yulan, Liang, Hao, Cui, Ping, Ye, Li, Huang, Jiegang“…Additionally, the α-diversity of skin microbiota was down-regulated at multiple time points following SARS-CoV-2 infection (P < 0.05). …”
Publicado 2023
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1041500por Pham, Thi Anh Mai, Forse, Rachel, Codlin, Andrew J., Phan, Thi Hoang Yen, Nguyen, Thanh Thi, Nguyen, Nga, Vo, Luan Nguyen Quang, Dat, Phan Thuong, Minh, Ha Dang Thi, Nguyen, Lan Huu, Nguyen, Hoa Binh, Nguyen, Nhung Viet, Bodfish, Miranda, Lönnroth, Knut, Wingfield, Tom, Annerstedt, Kristi Sidney“…Ninety-four people with MDR-TB being treated with a nine-month TB regimen were surveyed at three time points: after two weeks of treatment initiation, completion of the intensive phase and the end of the treatment (approximately five and 10 months post-treatment initiation respectively). …”
Publicado 2023
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