“…Although higher Indigenous drowning rates prevailed, no significant changes over time are concerning. Equally the apparent over-representation of Indigenous adolescent females should be weighed against the absence of drowning among Indigenous male adolescents in the same age group in consecutive years of the study. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: A total of 49 non-diabetic (22 obese, 19 overweight and 8 lean) and 42 T2D (31 obese, 9 overweight and 2 lean) adipose tissue samples were obtained by abdominal subcutaneous fat pad biopsy and IRAK-1 expression was determined using real-time RT-PCR, immunohistochemistry, and confocal microscopy. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: These data, for the first time, documented the EMT/stemness-maintenance in therapy-resistant PC-CSCs. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The two-year survivorship for the study group was 82%. The mean time from arthroscopy to joint replacement was 18.4 months (range 3.5-38.5 months). …”
Enlace del recurso
Enlace del recurso

“…In addition, the correlation between TSS CpG density and expression suggests increased mutation rates at CpG sites play a significant role in adaptive evolution by reducing CpG density at TSS over time, resulting in higher methylation levels in these regions and more permanent changes to lower gene expression. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The modifying effects of mode of administration, year of publication, study design, time interval between administrations, mean age of participants and publication type were examined. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…All patients were available for evaluation at an average 22.7 months follow up (range 6-49 months). Average age at the time of surgery was 14.5 years (range 13-17 years). …”
Enlace del recurso
Enlace del recurso

“…The study tested the hypothesis that female athletes who sustained a second ACL injury would demonstrate altered lower extremity coordination patterns indicative of persistent neuromuscular deficits at the time of return to sport compared to female athletes who would not subsequently sustain a second ACL injury. …”
Enlace del recurso
Enlace del recurso

“…This pattern may reverse over time, as graft-tunnel healing progresses (1-year followup testing is planned). …”
Enlace del recurso
Enlace del recurso

“…At 90 degrees of knee flexion, there is a 1.6 fold increase in ACL graft force between a high-tension ACL graft and isometric ACL graft at the time of surgery. High ACL graft force with joint motion appeared to be deleterious to early ACL graft-tunnel incorporation. …”
Enlace del recurso
Enlace del recurso

“…While these mechanical properties may translate into clinical differences, further studies are needed to understand their effects over time.…”
Enlace del recurso
Enlace del recurso

“…It was the first disease manifestation, was always present at the time of myositis diagnosis, and was associated with a high cutaneous score and chronicity. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, adaptation of a TE may be expressed only in part of the time and specific localities. REVIEWERS: Reviewed by Eugene Koonin, Limsoon Wong and Fyodor Kondrashov. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The NRS scores both at rest and with coughing show that there were no significant differences between D1 group and S group at each time point after surgery (P > 0.05). LOS of group D2 was higher than S and D1 groups at 1 hour after surgery (P < 0.05), BCS of group D2 was higher than S and D1 groups at 4, 8, and 16 hours after surgery (P < 0.05), and FAS of group D2 was higher than S and D1 groups at 48 and 72 hours after surgery (P < 0.05). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: In the EDATE observational study, phosphodiesterase-type-5 (PDE5)-inhibitor pretreated or naïve ED patients who started or switched to TAD-OaD were prospectively followed for 6 months. Time to discontinuation of TAD-OaD was estimated using the Kaplan-Meier product-limit method at Months 2, 4, and 6 in subgroups stratified by age (18 − 65 years and >65 years), PDE5-inhibitor pretreatment, ED-severity (mild, moderate, severe), and presence or absence of relevant comorbidities (BPH, diabetes, CVD, hypertension, dyslipidemia). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Odds ratios (ORs) with 95 % confidence interval (CI) were used to analyze the strength of the association between PCSK9 E670G polymorphism and the susceptibility to CAD. At the same time, the pooled standardized mean difference (SMD) with 95 % CI was used for the meta-analysis of PCSK9 E670G polymorphism and lipid levels. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: Investigating the extent of ASE across 18 bovine tissues in one cow and two tissues in 20 cows demonstrated 1) ASE is pervasive in cattle, 2) the ASE is often MAE but ranges from MAE to slight overexpression of the major allele, 3) the ASE is most often tissue specific and that more than half the time displays divergent allele specific expression patterns across tissues, 4) across all genes there is a slight bias towards expression of the paternal allele and 5) genes expressing the same parental allele are clustered together more than expected by chance, and there are several runs of large numbers of genes expressing the same parental allele. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The MRI outcomes—fat fraction, transverse relaxation time (T2), and magnetisation transfer ratio (MTR)—were analysed during the 12-month follow-up, by measuring correlation with functionally relevant clinical measures, and for T2 and MTR, sensitivity in muscles with fat fraction less than the 95th percentile of the control group. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…There was significantly greater reduction in migraine pain intensity with AVP-825 vs oral sumatriptan in the first 30 minutes post-dose (least squares mean SPID-30 = 10.80 vs 7.41, adjusted mean difference 3.39 [95% confidence interval 1.76, 5.01]; P < .001). At each time point measured between 15 and 90 minutes, significantly greater rates of pain relief and pain freedom occurred with AVP-825 treatment compared with oral sumatriptan. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, we report for the first time an association between a CLOCK polymorphism and stroke in T2D subjects, suggesting that core clock genes may significantly contribute to increased CVD risk in T2D. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso