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  1. 1041781
    “…It has the potential to delay the start of projects, affect recruitment time, incur extra research costs and disadvantage PPI. …”
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    A SHARED study-the benefits and costs of setting up a health research study involving lay co-researchers and how we overcame the challenges
  2. 1041782
    “…Although overall age-standardised death rates decreased by 29·0% (28·7 to 29·3) from 1990 to 2015, the rates of mortality decline in this period substantially varied across the prefectures, ranging from −32·4% (−34·8 to −30·0) to −22·0% (−20·4 to −20·1). During the same time period, the rate of age-standardised DALYs was reduced overall by 19·8% (17·9 to 22·0). …”
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    Population health and regional variations of disease burden in Japan, 1990–2015: a systematic subnational analysis for the Global Burden of Disease Study 2015
  3. 1041783
    “…Ocular Surface Disease Index scores, Schirmer Ι test, tear meniscus height, the first breakup of tear film occurrence (NIKBUT-first), and the average time of all breakup incidents (NIKBUT-average) values were significantly lower for the T2DM groups than for the healthy group. …”
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    Early central and peripheral corneal microstructural changes in type 2 diabetes mellitus patients identified using in vivo confocal microscopy: A case-control study
  4. 1041784
    por Yu, Hong, Gao, Feng, Jiang, Liren, Ma, Shuoxin
    Publicado 2017
    “…The client apps automatically capture FoVs at up to 12-megapixel resolution and process them in real-time to track the operation of users, then give instant feedback of guidance. …”
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    Development of a Whole Slide Imaging System on Smartphones and Evaluation With Frozen Section Samples
  5. 1041785
    “…CD8 T-cell responses were detected in 8%, 18%, and 14% of subjects in groups 1, 2, and 3, respectively, at the same time point. CONCLUSION: The HSV529 vaccine was safe, well-tolerated, and immunogenic, eliciting significant neutralizing, gD, and ADCC-mediating antibodies, and modest cellular immune responses in HSV seronegative individuals. …”
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    A Replication-Defective Herpes Simplex Virus (HSV)-2 Vaccine, HSV529, is Safe and Well-Tolerated in Adults with or without HSV Infection and Induces Significant HSV-2-Specific Antibody Responses in HSV Seronegative Individuals
  6. 1041786
    “…Extending closed loop filtration over time demonstrates capability for rapid sterilization of the CSF. …”
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    Feasibility of Neurapheresis™ as a Therapy for Multidrug Resistant Gram-negative Bacterial Meningitis
  7. 1041787
    “…In comparison to Ph1 subjects, SER-109 engraftment was significantly reduced and delayed among Ph2 subjects at all time points (Fig 2). Moreover, Ph1b subjects who received higher doses of SER-109 than that used in Ph2 had increased levels of engraftment. …”
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    Gastrointestinal Tract Microbiome Dynamics Following Treatment with SER-109, an Investigational Oral Microbiome Therapeutic to Reduce the Recurrence of Clostridium difficile Infection (CDI)
  8. 1041788
    “…Pathogen cfDNA in BSI patients, quantified as MPM, declined over time during treatment. S. aureus MPM declined more slowly than gram-negative MPM and was significantly higher than gram-negative MPM at day 6 (P < 0.001). …”
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    Direct Detection and Quantification of Bacterial Cell-free DNA in Patients with Bloodstream Infection (BSI) Using the Karius Plasma Next Generation Sequencing (NGS) Test
  9. 1041789
    “…RESULTS: VL-2397 concentration-time data in humans revealed nonlinear PK behavior consistent with highly-bound compounds. …”
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    Pharmacokinetic-Pharmacodynamic Target Attainment Analysis to Support VL-2397 Dose Selection for a Phase 2 Trial in Patients with Invasive Aspergillosis
  10. 1041790
    “…The incidence of IPD due to STs 19A and 3 over time in children and adults is shown in the Figures. …”
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    Changing Epidemiology of Invasive Pneumococcal Disease due to Conjugate Vaccine Serotypes in Toronto, Canada After Introduction of a Routine Pediatric PCV13 Program
  11. 1041791
    “…CONCLUSION: Antibody levels in adolescents and young adults primed with 4CMenB waned over time but were higher at 4 years post-primary vaccination than for vaccine-naïve individuals at baseline. …”
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    Persistence of Bactericidal Activity at 4 Years After 2 Primary Doses of a Recombinant, 4-Component, Meningococcal Serogroup B Vaccine (4CMenB) and Response to a Booster Dose in Adolescents and Young Adults
  12. 1041792
    por Syros, Ioannis
    Publicado 2017
    “…CB therapy and psychoeducation can provide structure and support when anxiety and avoidance discourage trauma exploration, while therapeutic gains seem to be maintained over time. Future directions characterize (a) research on promising practices and the potential of new interventions, (b) the exploration of providing interventions to specific cultural populations, as well as (c) the further study of those elements that ‘work’ in CB treatments, and their importance in empowering new health professionals trained in these approaches.…”
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    Cognitive behavioral therapy for the treatment of PTSD
  13. 1041793
    “…Furthermore, continuous arousal during the course of time may produce difficulty in the hippocampus’s ability to manage in the future highly stressful events. …”
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    Post-traumatic stress reactions in young victims of road traffic accidents
  14. 1041794
    “…Nine heart failure patients (8 men, 1 woman; mean age of 57.0 years) were identified. The average time between the cardiac MRI and radionuclide angiography exams was 38.9 days (range: 1 - 119 days). …”
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    Right ventricular functional analysis utilizing first pass radionuclide angiography for pre-operative ventricular assist device planning: a multi-modality comparison
  15. 1041795
    “…Translocation of Fe(2)O(3) ENM was determined by ICP-MS analysis of cell lysates and basolateral compartment fluid over time. RESULTS: It was demonstrated that the interactions of iENMs with food and GIT components influenced nanoparticle fate and transport, biokinetics and toxicological profile. …”
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    An integrated methodology for assessing the impact of food matrix and gastrointestinal effects on the biokinetics and cellular toxicity of ingested engineered nanomaterials
  16. 1041796
    “…There were no significant differences among the three groups in maximum pain scores (p=0.88) or median opioid consumption (p=0.47) over time. There were more postoperative hallucinations (p=0.01) and nightmares (p=0.03) with escalating doses of ketamine. …”
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    Intraoperative ketamine does not affect postoperative delirium or pain after major surgery in older adults: an international, multicentre, double-blind, randomised clinical trial
  17. 1041797
    “…Mobile phone-based gait measures may provide a more readily accessible and less-time consuming measure of gait, while further providing clinicians with longitudinal gait measures that are currently difficult to obtain.…”
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    Mobile Phone-Based Measures of Activity, Step Count, and Gait Speed: Results From a Study of Older Ambulatory Adults in a Naturalistic Setting
  18. 1041798
    “…CONCLUSIONS: This study has - for the first time - linked testis maturation to specific miRNAs and their inversely correlated expressed targets in Atlantic salmon. …”
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    Integrative testis transcriptome analysis reveals differentially expressed miRNAs and their mRNA targets during early puberty in Atlantic salmon
  19. 1041799
    por Tariq, Khurram, Rana, Fauzia
    Publicado 2013
    “…Pathologic stage at the time of diagnosis for TNBC vs. non-TNBC patients was as follows: stage 0, 15.79% vs. 11.37% (P = 0.4332); stage 1, 34.21% vs. 30.98% (P = 0.6890); stage 2, 28.98% vs. 37.25% (P = 0.3205); stage 3, 18.42% vs. 17.25% (P = 0.0.8591); and stage 4, 3.63% vs. 3.14% (P = 0.8651). …”
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    TNBC vs. Non-TNBC: A Five-Year Retrospective Review of Differences in Mean Age, Family History, Smoking History and Stage at Diagnosis at an Inner City University Program
  20. 1041800
    “…Top barriers to seeking help to improve emotional wellness during the perinatal period were: no time to seek help/assistance (130/174, 74.7%), lack of resources available in the health care system (126/174, 72.4%), financial costs associated with services (118/174, 67.8%), and feeling that one should be able to do it alone (113/174, 64.9%). …”
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    HealthyDads.ca: What Do Men Want in a Website Designed to Promote Emotional Wellness and Healthy Behaviors During the Transition to Parenthood?
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