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1042101por Shao, Qingqing, Liu, Tong, Wang, Wenjia, Duan, Qianni, Liu, Tianli, Xu, Lijun, Huang, Guangying, Chen, Zhuo“…To explore the mechanism by which JZ-1 regulates autophagy, western blotting and real-time quantitative PCR (qRT-PCR) were used to determine the expression of phosphoinositide 3-kinase (PI3K)/Akt/mTOR pathway proteins and to detect changes in critical molecules in the pathway after the application of a PI3K inhibitor. …”
Publicado 2020
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1042102“…RESULTS: High prices of medicinal plants are widely considered to reflect resource scarcity. Real-time market prices for three of the four very different TCM species we studied all showed major price fluctuations. …”
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1042103“…Women with dilated tubes found at the time of hysterosalpingography are at highest risk, and prophylactic antibiotics (e.g., doxycycline) should be given. …”
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1042104“…Infection control professionals (ICP) full-time equivalents (FTEs) per 100 beds increased from a mean of 0.5 (SD, 0.2) in 1999 to 0.8 (SD, 0.3) in 2005 (F = 90.8, P < .0001). …”
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1042105por Bulteau, Samuel, Laurin, Andrew, Volteau, Christelle, Dert, Cécile, Lagalice, Lydie, Schirr-Bonnans, Solène, Bukowski, Nicolas, Guitteny, Marie, Simons, Luc, Cabelguen, Clémence, Pichot, Anne, Tessier, Fabienne, Bonnin, Annabelle, Lepage, Adeline, Vanelle, Jean-Marie, Sauvaget, Anne, Riche, Valery-Pierre“…DISCUSSION: The purpose of our study is to check the cost-effectiveness of rTMS and we will discuss its economic impact over time. In the case of significant decrease in the depression costs and expenditures associated with a good long-term prognosis (sustained response and remission) and tolerance, rTMS could be considered as an efficient treatment within the armamentarium for resistant unipolar depression. …”
Publicado 2020
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1042106por Cegolon, L., Maso, G., Heymann, W. C., Bortolotto, M., Cegolon, A., Mastrangelo, G.“…The adjusted mean LoS was higher in IVD than SVD, and although a decline of LoS > ED and mean LoS over time was observed for both VDM, there was little variation of the adjusted mean LoS by nationality of the woman and by level of pregnancy risk (high vs. low). …”
Publicado 2020
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1042107por Tucker, Bradford S., Campbell, Richard E., Tjoumakaris, Fotios P., Freedman, Kevin B., Miller, Lawrence S., Maria, Daniel Santa, Leider, Morgan, Garza, Jamie“…Furthermore, while WOMAC scores continued to improve for both treatment groups during the 6 months to 1 year period, the placebo group returned to baseline during the same time interval. The efficacy of SVF injections, in combination with its safety and ease of use, support its’ use as a treatment option for symptomatic knee osteoarthritis.…”
Publicado 2020
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1042108por Kiwanuka, Julius, Mukulu Waila, Jacinta, Muhindo Kahungu, Methuselah, Kitonsa, Jonathan, Kiwanuka, Noah“…CONCLUSION: The risk of loss to follow up increased with time and was higher among patients who started ART within seven days following HIV diagnosis, higher among patients without a telephone set, lower among patients aged ≥ 25 years, lower among patients with at least primary education and lower among patients with BMI of ≥ 30. …”
Publicado 2020
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1042109por Blauvelt, Andrew, Leonardi, Craig L., Gooderham, Melinda, Papp, Kim A., Philipp, Sandra, Wu, Jashin J., Igarashi, Atsuyuki, Flack, Mary, Geng, Ziqian, Wu, Tianshuang, Camez, Anne, Williams, David, Langley, Richard G.“…Rates of treatment-emergent adverse events were similar between risankizumab (186 [45.7%]) and placebo (49 [49.0%]) in part A1 and remained stable over time. CONCLUSIONS AND RELEVANCE: Risankizumab showed superior efficacy compared with placebo through 16 weeks and treatment withdrawal through 2 years. …”
Publicado 2020
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1042110“…A possible variant of the use of these cockerels could be organic or free-range farming, where it is desirable that the animals are fattened for a longer period of time, are more physically active, and graze pasture vegetation. …”
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1042111por Kopf, Sebastian, Beaufils, Philippe, Hirschmann, Michael T., Rotigliano, Niccolò, Ollivier, Matthieu, Pereira, Helder, Verdonk, Rene, Darabos, Nikica, Ntagiopoulos, Panagiotis, Dejour, David, Seil, Romain, Becker, Roland“…Thereafter, the comments of the members of the rating group were incorporated by the steering group and the consensus was submitted to the rating group a second time. Once a general consensus was reached between the steering and rating groups, the finalized question and answer sets were submitted for final review by the peer review group composed of representatives of the ESSKA-affiliated national societies. …”
Publicado 2020
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1042112“…Despite the many difficulties, society needs new pain killers at the same time that notable pharma are pulling out, despite the economic opportunity. …”
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1042113por Guo, Rongxing“…The Taiwan Strait became a forbidden boundary in 1949 when the Nationalist-led government fled to Taiwan and, at the same time, the Communist-led government was founded on the mainland. …”
Publicado 2013
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1042114por Bueno-Hernández, Nallely, Esquivel-Velázquez, Marcela, Alcántara-Suárez, Raúl, Gómez-Arauz, Angélica Y., Espinosa-Flores, Aranza J., de León-Barrera, Karen L., Mendoza-Martínez, Viridiana M., Sánchez Medina, Gabriela A., León-Hernández, Mireya, Ruiz-Barranco, Alejandra, Escobedo, Galileo, Meléndez, Guillermo“…All participants underwent a 3-h oral glucose tolerance test (OGTT) preceded by consuming sucralose or placebo 15 min before glucose load, at two time points: week zero (Wk0) and week ten (Wk10). …”
Publicado 2020
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1042115por Lescure, Francois-Xavier, Bouadma, Lila, Nguyen, Duc, Parisey, Marion, Wicky, Paul-Henri, Behillil, Sylvie, Gaymard, Alexandre, Bouscambert-Duchamp, Maude, Donati, Flora, Le Hingrat, Quentin, Enouf, Vincent, Houhou-Fidouh, Nadhira, Valette, Martine, Mailles, Alexandra, Lucet, Jean-Christophe, Mentre, France, Duval, Xavier, Descamps, Diane, Malvy, Denis, Timsit, Jean-François, Lina, Bruno, van-der-Werf, Sylvie, Yazdanpanah, Yazdan“…All samples were refrigerated and shipped to laboratories in the National Reference Center for Respiratory Viruses (The Institut Pasteur, Paris, and Hospices Civils de Lyon, Lyon, France), where RNA extraction, real-time RT-PCR, and virus isolation and titration procedures were done. …”
Publicado 2020
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1042116por Verity, Robert, Okell, Lucy C, Dorigatti, Ilaria, Winskill, Peter, Whittaker, Charles, Imai, Natsuko, Cuomo-Dannenburg, Gina, Thompson, Hayley, Walker, Patrick G T, Fu, Han, Dighe, Amy, Griffin, Jamie T, Baguelin, Marc, Bhatia, Sangeeta, Boonyasiri, Adhiratha, Cori, Anne, Cucunubá, Zulma, FitzJohn, Rich, Gaythorpe, Katy, Green, Will, Hamlet, Arran, Hinsley, Wes, Laydon, Daniel, Nedjati-Gilani, Gemma, Riley, Steven, van Elsland, Sabine, Volz, Erik, Wang, Haowei, Wang, Yuanrong, Xi, Xiaoyue, Donnelly, Christl A, Ghani, Azra C, Ferguson, Neil M“…These individual-case data were used to estimate the time between onset of symptoms and outcome (death or discharge from hospital). …”
Publicado 2020
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1042117por Vinclair, Camille, De Montmollin, Etienne, Sonneville, Romain, Reuter, Jean, Lebut, Jordane, Cally, Radj, Mourvillier, Bruno, Neuville, Mathilde, Ruckly, Stéphane, Timsit, Jean-François, Bouadma, Lila“…MAIN RESULTS: 158 consecutive patients were included (male sex: 75.9%; median and interquartile range: age: 59 [47–66], Simplified Acute Physiology Score II: 55 [39–66], Sepsis-related Organ Failure Assessment Score: 9 [7–12], time on VA-ECMO: 7.5 [4–12] days). Among them 145 (91.8%) developed an AKI during the intensive care unit (ICU) stay and 85 (53.8%) needed renal replacement therapy (RRT). 59.9% (91/152), 60.5% (89/147) and 85.1% (120/141) evaluable patients had a MAKE-30, MAKE-90 and MAKE-360, respectively. …”
Publicado 2020
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1042118por Chew, Nicholas W.S., Lee, Grace K.H., Tan, Benjamin Y.Q., Jing, Mingxue, Goh, Yihui, Ngiam, Nicholas J.H., Yeo, Leonard L.L., Ahmad, Aftab, Ahmed Khan, Faheem, Napolean Shanmugam, Ganesh, Sharma, Arvind K., Komalkumar, R.N., Meenakshi, P.V., Shah, Kenam, Patel, Bhargesh, Chan, Bernard P.L., Sunny, Sibi, Chandra, Bharatendu, Ong, Jonathan J.Y., Paliwal, Prakash R., Wong, Lily Y.H., Sagayanathan, Renarebecca, Chen, Jin Tao, Ying Ng, Alison Ying, Teoh, Hock Luen, Tsivgoulis, Georgios, Ho, Cyrus S., Ho, Roger C., Sharma, Vijay K.“…We postulate that this association may be bi-directional, and that timely psychological interventions for healthcare workers with physical symptoms should be considered once an infection has been excluded.…”
Publicado 2020
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1042119por Yip, Terry Cheuk-Fung, Wong, Grace Lai-Hung, Tse, Yee-Kit, Yuen, Becky Wing-Yan, Luk, Hester Wing-Sum, Lam, Marco Ho-Bun, Li, Michael Kin-Kong, Loo, Ching Kong, Tsang, Owen Tak-Yin, Tsang, Steven Woon-Choy, Chan, Henry Lik-Yuen, Wing, Yun-Kwok, Wong, Vincent Wai-Sun“…Importantly, 569 (38.9%) patients were not known to have liver diseases at the time of liver-related events. The median age at HCC diagnosis (61 [range 26–83] years) was older and the median overall survival (8.0 [95% CI 5.0–10.9] months) after HCC diagnosis was shorter in this cohort of psychiatric patients than other reports from Hong Kong. …”
Publicado 2020
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1042120por Reis, Zilma Silveira Nogueira, Gaspar, Juliano De Souza, Vitral, Gabriela Luiza Nogueira, Abrantes, Vitor Barbosa, de-Souza, Ingrid Michelle Fonseca, Moreira, Maria Tereza Silveira, Lopes Pessoa Aguiar, Regina Amélia“…BACKGROUND: The correct dating of pregnancy is critical to support timely decisions and provide obstetric care during birth. …”
Publicado 2020
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